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Photodynamic anticancer treatment causes cell death via AMP activated protein kinase (AMPK)
Area: Cancer
A recent development in cancer treatment is the photodynamic therapy (PDT). Irradiation with light of a specific wavelength induces cell death after treatment with a photo-sensitizer. A study from April of this year revealed that It has previously been known that MAPKs were involved in signaling leading to cell death, the recent study is the first report that AMP-activated protein kinase plays a crucial role in PDT induced cell death. The study utilized an anti-phospho-JNK (MAPK) antibody that can be purchased on antibodies-online.
The study can be found at:
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