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Nestin expression controls TGF-beta receptor signaling in astrocytoma cells

Nestin is a type VI intermediate filament protein, expressed mostly in nerve cells where they are implicated in the radial growth of the axon. Nestin has recently received attention as a marker for detecting newly formed endothelial cells. A recent study in the journal Oncogene shows, that diminished integrin expression in astrocytoma cells can lead to a reduced TGFbeta receptor signaling in tumor-associated endothelial cells. The anti-nestin antibody utilized in this study is available on antibodies-online.
More antibodies against nestin are available here: show »all anti-nestin antibodies.

The research article can be found here:
29.06.2010 | David Kitz Kramer   RSS Feed   Research News   Bookmark and Share

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