Area: Metabolism, Diabetes Diabetic Nephropathy: Preservation of kidney function with combined inhibition of NADPH oxidase and angiotensin-converting enzyme A recent study aimed to determine if there are added renoprotective benefits seen by combining angiotensin-converting enzyme-1 inhibitors (ACEi) with blockade of NADPH oxidase in antihypertensive therapies, and found that a combination of NADPH oxidase blockade with ACE inhibitors is a promising regimen. The study was performed using an ELISA kit against kidney injury molecule 1 (Kim-1). More ELISA kits may be found here: » show all ELISA kits. The link to the original scientific communication can be found below: Source: » American Journal of Nephrology, Vol. 32, No. 1, 2010. Preservation of Kidney Function with Combined Inhibition of NADPH Oxidase and Angiotensin-Converting Enzyme in Diabetic Nephropathy, Vicki Thallas-Bonke et. al.