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Protein crystal structure helps solving the role of ARL6 in Bardet-Biedl Syndrome

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belongs to the ARF family of GTP-binding proteins. Many members of the large family of GTPases are known to play essential roles in modulating membrane trafficking and cytoskeletal functions. A new study presented the crystal structure of ARL6 and thereby helped to determine a mechanistic explanation for such pathogenic alterations like Bardet-Biedl syndrome. The study was performed using an ARL6 antibody available on antibodies-online.

On antibodies-online you may find a list of

The full study is available here