Once you can produce it in a flask, what next? The focus of this meeting will be on techniques for the bioproduction of usable quantities of biologic materials, specifically recombinant proteins, monoclonal antibodies, cytokines viruses and other secreted cellular products from eukaryotic cells.  » Read more

Green Fluorescent Protein (GFP): An often cited anti-GFP antibody on antibodies-online has already been cited in the renowned science journal PLOS one in 2011. The immunogen used for production of this antibody is a GFP fusion protein corresponding to the full length amino acid sequence (246aa) derived from the jellyfish Aequorea victoria.

Somatic motor neuron sub-populations are differentially vulnerable to degeneration. A recent study utilized an anti-soluble Guanylate Cyclase 1 alpha 3 (GUCY1A3) antibody to revealed that guanylate cyclase 1A3 expression varies between cells with different susceptibilities.  » Read more

For many years there had been a decline in the development of new vaccines to treat some of the world most common diseases. Very often research and development being slow, trials being unsuccessful, and vaccines not being well received discouraging pharmaceutical companies. However by the turn of the century with the development of new technologies, production and research methods, and the need to provide the ever expanding world population with solutions to health concerns the industry has expanded and reversed its declining trend.  » Read more

A recent study in the Journal of Virus research investigated the interaction of Hepatitis B virus (HBV) core protein (HBc) with antiviral factors. For the study on HBc an anti-HBc antibody from antibodies-online.com has been utilized that can be used for various applications, such as flow cytometry (FACS), ELISA, immunohistochemistry (IHC) and immunoprecipitation (IP).  » Read more

Photosynthesis produces reactive oxygen species, such as hydrogen peroxide, which are reduced by peroxiredoxins (Prx). Peroxiredoxin enzymes are ubiquitous in all kingdoms of life. antibodies-online offers antibodies against various peroxidoxins like Prx Q for example, which acts by reducing hydroperoxides. A recent study investigated the functions of peroxidoxins in Arabidopsis thaliana using this antibody.  » Read more

Infection of quiescent cells by human cytomegalovirus (HCMV) elicits severe cell cycle deregulation resulting in a G1/S arrest, which can be partly attributed to the inactivation of the anaphase-promoting complex (APC). Various anti-CMV antibodies against ICP36, ICP8, UL83 and pp28 were used in a recent study, addressing the question what causes this effect. The results suggest that a viral early gene product is involved in APC degradation.  » Read more

A recent study utilized an adiponektin ELISA kit that is available on antibodies-online. The study examined whether plasma adiponectin levels are correlated with osteonecrosis of the femoral head (ONFH). Adiponektin may be a useful biomarker, since patients with nontraumatic ONFH had significantly lower plasma levels of adiponectin than the healthy controls. Other factors, such as plasma LDL, HDL, apoA1, apo B, Cholesterol, TGs and CRP showed no correlation.  » Read more

Red fluorescent protein (RFP) can be used as a label of forced expression of recombinant proteins in various cell systems. The monoclonal 5F8 antibody recognizes various red fluorescent proteins derived from DsRed and RFP-tagged fusion proteins, like RFP1, Cherry, Plum and Orange, but not GFP. A recent study demonstrates a successful application of the antibody in transfected bone marrow stromal cells.  » Read more

A current study investigated the effects of GluR1 in the hypothalamus, providing biochemical and cellular mechanisms which regulate food intake. The study utilized an anti-phospho-Ser845 and an anti-phospho-Ser831 GluR1 antibody which are available on antibodies-online.  » Read more

Peroxiredoxins act by reducing hydroperoxides, which naturally occur as a side-product of the photosynthetic process. A recent study utilized an anti-peroxiredoxin antibody in order to address the question of break-down of reactive oxygen species in Arabidopsis thaliana chloroplasts. Here you may find the applied »antibody against ATPRX Q. On antibodies-online a large number of additional »peroxiredoxin antibodies can be found.  » Read more

A study published this year in the Journal Oncogene addresses the expressional regulation of Bmi1 and its downstream targets. The research was carried out in neuroblastoma (NB) cells and addressed questions of epigenetic alterations and its roles in the tumorigenesis of NB. Using an antibody specific for Bmi1 it was revealed that the expression of Bmi1 resulted in the acceleration of proliferation and colony formation in NB cells.  » Read more

A recent study investigated the impact of iron deficiency on bioenergetic pathways in Chlamydomonas, a genus of green alga. The researchers found that acetate-grown iron-limited cells maintained high growth rates by suppressing photosynthesis and increasing respiration instead. In order to study this phenomenon the researcher used antibodies that are available on antibodies-online, namely an anti-plasma membrane ferroxidase (or anti-FOX1) antibody and an anti-COXII - mitochondrial cytochrome oxidase subunit II antibody.  » Read more