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anti-Human CD40 antibody for Functional Studies

Recommended CD40 Antibody (supplied by: Log in to see )

Antigen
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
  • 2310042E05Rik
  • AI326936
  • Bp50
  • C87049
  • C130077D06Rik
  • CDW40
  • DCTN-50
  • GMP23-48K
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • p50
  • RBP50
  • T-BAM
  • Tnfrsf5
  • TNFRSF5
  • TNFSF5
  • TRAP
Reactivity
Human
600
296
57
13
11
8
7
5
4
2
1
1
1
1
Host
Mouse
476
207
154
24
7
2
Clonality
Monoclonal
Conjugate
This CD40 antibody is un-conjugated
92
90
51
24
20
17
14
12
12
11
9
8
8
8
8
8
8
8
8
8
7
6
6
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
557
198
197
105
88
76
70
49
47
20
19
11
8
8
6
4
3
3
2
2
2
2
1
1
1
1
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Catalog No. ABIN1106354
$ 308.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008774256 ABIN111321 Func FACS IHC (fro) IHC (p) Mouse IgG1 Log in to see MAB89 4
0.0008774256 ABIN610077 Func FACS IP ELISA PE Mouse IgG1 Log in to see BE-1 3
0.0008774256 ABIN610290 Func FACS ELISA Biotin Mouse IgG1 Log in to see EA-5 2
0.0008774256 ABIN610291 Func FACS ELISA FITC Mouse IgG1 Log in to see EA-5 2
0.0008774256 ABIN610074 Func FACS IP ELISA Mouse IgG1 Log in to see BE-1 2
0.0008774256 ABIN610078 Func FACS IP ELISA Mouse IgG1 Log in to see BE-1 3
0.0008774256 ABIN610075 Func FACS IP ELISA Biotin Mouse IgG1 Log in to see BE-1
0.0008774256 ABIN610076 Func FACS IP ELISA FITC Mouse IgG1 Log in to see BE-1
0.0008774256 ABIN610292 Func FACS ELISA PE Mouse IgG1 Log in to see EA-5
0.0008774256 ABIN282202 Func FACS Mouse IgG1 kappa Log in to see 5C3
0.0008774256 ABIN610289 Func FACS ELISA Mouse IgG1 Log in to see EA-5
0.0008774256 ABIN211845 Func FACS Mouse IgG1 Log in to see
0.0008774256 ABIN786599 Func FACS IHC (p) Mouse IgG1 Log in to see G28-5 4
0.0008774256 ABIN786601 Func FACS IHC (p) Mouse IgG1 Log in to see mAb89 10
0.0008774256 ABIN2618532 Func FACS IHC (p) ELISA Mouse IgG1 Log in to see EA-5
0.0008774256 ABIN2567682 Func FACS Mouse IgG1 kappa Log in to see 5C3
0.0008774256 ABIN2567683 Func FACS Mouse IgG1 kappa Log in to see 5C3
0.0008774256 ABIN1722607 FACS Func IHC (fro) WB Mouse IgG1 Log in to see B-B20
0.0008774256 ABIN2962194 Func FACS IHC (p) ELISA Mouse IgG1 Log in to see EA-5
0.0008774256 ABIN4293030 FACS Func IHC IHC (fro) Mouse IgG1 kappa Log in to see 5C3

Top referenced anti-CD40 antibody for Functional Studies

Similar anti-CD40 Antibodies

Application / Reactivity Human
ELISA 155 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 340 Antibodies
Functional Studies (Func) 23 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 17 Antibodies
Immunofluorescence (IF) 44 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 64 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 3 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 69 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 70 Antibodies
Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)) 1 Antibodies
Immunoprecipitation (IP) 53 Antibodies
Immunostaining (ISt) 1 Antibodies

General

Antigen CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
Reactivity Human
(600), (296), (57), (13), (11), (8), (7), (5), (4), (2), (1), (1), (1), (1)
Host Mouse
(476), (207), (154), (24), (7), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD40 antibody is un-conjugated
(92), (90), (51), (24), (20), (17), (14), (12), (12), (11), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (7), (6), (6), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
(557), (198), (197), (105), (88), (76), (70), (49), (47), (20), (19), (11), (8), (8), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CD40 Antibody

Target Details CD40 Application Details Handling References for anti-CD40 Antibody (ABIN1106354) Images
Specificity This antibody recognises the Bp50 antigen, a 48 kDa protein.
Purification Ion Exchange Chromatography
Sterility 0.22 μm filtered
Immunogen Raji cell line.
Clone B-B20
Isotype IgG1

Target Details CD40

Product Details anti-CD40 Antibody Application Details Handling References for anti-CD40 Antibody (ABIN1106354) Images back to top
Antigen
Alternative Name CD40 (CD40 Antibody Abstract)
Background CD40 is a costimulatory molecule of the TNF receptor superfamily and is expressed on many cell types, such as B cells, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts or vascular smooth muscle cells. Interaction of CD40 and its ligand CD154 (CD40L) is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. In monocytes/macrophages CD40 engagement induces production of pro-inflammatory cytokines and chemokines. CD40-CD154 interactions are also critical for development of CD4 T cell-dependent effector functions. CD40 links innate and adaptive immune responses to bacterial stimuli and serves as an important regulator affecting functions of other costimulatory molecules.Synonyms: B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Gene ID 958
NCBI Accession NP_001241
UniProt P25942
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling

Application Details

Product Details anti-CD40 Antibody Target Details CD40 Handling References for anti-CD40 Antibody (ABIN1106354) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD40 Antibody Target Details CD40 Application Details References for anti-CD40 Antibody (ABIN1106354) Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free.
Preservative Without preservative
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-CD40 Antibody (ABIN1106354)

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling Images back to top
Background publications

Durali, de Goër de Herve, Giron-Michel, Azzarone, Delfraissy, Taoufik: "In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment." in: Blood, Vol. 102, Issue 12, pp. 4084-9, 2003

Jeannin, Delneste, Lecoanet-Henchoz, Gauchat, Ellis, Bonnefoy: "CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells." in: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15613-9, 1997

Vermot-Desroches, Marchand, Roy, Wijdenes: "Heterogeneity of antigen expression among human umbilical cord vascular endothelial cells: identification of cell subsets by co-expression of haemopoietic antigens." in: Immunology letters, Vol. 48, Issue 1, pp. 1-9, 1996

Images

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling References for anti-CD40 Antibody (ABIN1106354) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5) (ABIN1106354) anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody