anti-Monkey CD40 antibody for Western Blotting

Recommended CD40 Antibody (supplied by: Log in to see )

Antigen
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
  • AI326936
  • Bp50
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • p50
  • CDW40
  • TNFRSF5
  • TNFSF5
  • 2310042E05Rik
  • C130077D06Rik
  • C87049
  • DCTN-50
  • GMP23-48K
  • RBP50
  • CD40 antigen
  • CD40 molecule, TNF receptor superfamily member 5
  • dynactin 2
  • LOC100349106
  • Cd40
  • CD40
  • Dctn2
Reactivity
Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
647
311
68
20
13
10
9
6
4
3
2
2
1
1
1
1
Host
Rabbit
506
213
168
23
6
4
Clonality
Polyclonal
Conjugate
This CD40 antibody is un-conjugated
88
85
51
24
24
21
17
15
14
13
12
9
9
9
9
9
9
9
8
7
7
7
7
6
6
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
580
244
207
157
111
103
101
65
47
34
19
15
13
13
9
6
6
4
3
3
3
3
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN222919
$ 265.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9058776 ABIN3183772 ELISA IHC WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN216805 WB Rabbit IgG AA 71-120 Log in to see Polyclonal
1 ABIN463276 WB Rabbit IgG AA 35-84 Log in to see Polyclonal
1 ABIN241644 WB Rabbit Log in to see Polyclonal
1 ABIN2618546 WB Rabbit IgG AA 20-37 Log in to see Polyclonal
1 ABIN1821837 WB Rabbit IgG Log in to see Polyclonal
1 ABIN4965150 WB Rabbit IgG Log in to see Polyclonal
1 ABIN5551136 WB Rabbit Log in to see Polyclonal
1 ABIN1002088 WB Rabbit Log in to see Polyclonal

General

Antigen CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
Reactivity Human, Monkey, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(647), (311), (68), (20), (13), (10), (9), (6), (4), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(506), (213), (168), (23), (6), (4)
Clonality
Polyclonal
Conjugate This CD40 antibody is un-conjugated
(88), (85), (51), (24), (24), (21), (17), (15), (14), (13), (12), (9), (9), (9), (9), (9), (9), (9), (8), (7), (7), (7), (7), (6), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(580), (244), (207), (157), (111), (103), (101), (65), (47), (34), (19), (15), (13), (13), (9), (6), (6), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-CD40 Antibody

Target Details CD40 Application Details Handling References for anti-CD40 antibody (ABIN222919) Images
Blocking Peptide Blocking peptide for this product available: ABIN412676
Specificity Detects 43 kDa CD40 protein in Western blot analysis
Purification Affinity purified
Immunogen Synthetic peptide corresponding to residues surrounding AA 261 of human CD40
Isotype IgG

Target Details CD40

Product Details anti-CD40 Antibody Application Details Handling References for anti-CD40 antibody (ABIN222919) Images back to top
Antigen
Alternative Name CD40 (CD40 Antibody Abstract)
Background CD40 is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L), a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center throμgh interaction with T cells expressing CD40L, and activation of CD4+ T cells. In non-hemopoitic cells such as epidermal basal cells, CD40 ligation serves as the signal for inhibition of cell growth and induction of differentiation. The cytoplasmic domain of CD40 interacts with TRAF6, a TNFR associated factor homolog that mediates signaling from CD40. Ligation of CD40 with its ligand preferentially induces stress-activated protein kinases in B lymphocytes.
Synonyms: CDW40, CDw40, p50, Bp50, MGC9013, TNFRSF5
Gene ID 958
UniProt P25942
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-CD40 Antibody Target Details CD40 Handling References for anti-CD40 antibody (ABIN222919) Images back to top
Application Notes Western blotting (0.5-4 μg/mL). However, the optimal conditions should be determined individually.
Restrictions For Research Use only

Handling

Product Details anti-CD40 Antibody Target Details CD40 Application Details References for anti-CD40 antibody (ABIN222919) Images back to top
Format Liquid
Concentration 0.2 mg/mL
Buffer 100 μg (0.2 mg/mL) immunoaffinity purified rabbit anti-CD40 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-CD40 antibody (ABIN222919)

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling Images back to top
Product cited in:

Gao, Wagner, Fankhaenel, Stojanovic, Schweyer, Panzner, Hecker: "CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis." in: Gut, Vol. 54, Issue 1, pp. 70-7, 2004

Images

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling References for anti-CD40 antibody (ABIN222919) back to top
Supplier Images
Western Blotting (WB) image for anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody (ABIN222919) Western blot analysis of CD40 expression in rat kidney tissue lysate.