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anti-Mouse (Murine) CD40 antibody for ELISA (Capture)

Recommended CD40 Antibody (supplied by: Log in to see )

Antigen
CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
  • 2310042E05Rik
  • AI326936
  • Bp50
  • C87049
  • C130077D06Rik
  • CDW40
  • DCTN-50
  • GMP23-48K
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • p50
  • RBP50
  • T-BAM
  • Tnfrsf5
  • TNFRSF5
  • TNFSF5
  • TRAP
Reactivity
Mouse (Murine)
606
301
57
13
11
8
7
5
4
2
1
1
1
1
1
Host
Hamster
482
211
154
23
9
2
Clonality
Monoclonal
Conjugate
This CD40 antibody is conjugated to FITC
94
91
52
24
20
17
14
12
12
11
9
8
8
8
8
8
8
8
8
8
7
6
6
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
ELISA (Capture)
567
200
199
107
88
78
72
49
48
22
19
11
8
7
6
4
3
3
2
2
2
2
1
1
1
1
1
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Available images

Catalog No. ABIN2662062
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008658908 ABIN2659266 ELISA (Capture) PE-Cy7 Rat IgG2a kappa Log in to see 3-23 3
0.0008658908 ABIN2661714 ELISA (Capture) ELISPOT (Capture) FITC Rat IgG2a kappa Log in to see 3-23 3
0.0008658908 ABIN2661078 ELISA (Capture) WB Biotin Rat IgG2a kappa Log in to see 3-23 4
0.0008658908 ABIN2659267 ELISA (Capture) PE-Cy7 Rat IgG2a kappa Log in to see 3-23 3
0.0008658908 ABIN2662061 ELISA (Capture) FITC Hamster IgM kappa, IgM Log in to see HM40-3 11
0.0008658908 ABIN2661713 ELISA (Capture) ELISPOT (Capture) FITC Rat IgG2a kappa Log in to see 3-23 3
0.0008658908 ABIN2661077 ELISA (Capture) WB Biotin Rat IgG2a kappa Log in to see 3-23 4

Top referenced anti-CD40 antibody for ELISA (Capture)

Similar anti-CD40 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 3 Antibodies
ELISA 50 Antibodies
ELISA (Capture) 8 Antibodies
ELISA (Detection) 2 Antibodies
ELISpot (Capture) (ELISPOT (Capture)) 2 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 224 Antibodies
Functional Studies (Func) 23 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 29 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 4 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 38 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies

General

Antigen CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) Antibodies
Reactivity Mouse (Murine)
(606), (301), (57), (13), (11), (8), (7), (5), (4), (2), (1), (1), (1), (1), (1)
Host Hamster
(482), (211), (154), (23), (9), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD40 antibody is conjugated to FITC
(94), (91), (52), (24), (20), (17), (14), (12), (12), (11), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (7), (6), (6), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA (Capture)
(567), (200), (199), (107), (88), (78), (72), (49), (48), (22), (19), (11), (8), (7), (6), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 11 references available
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Product Details anti-CD40 Antibody

Target Details CD40 Application Details Handling References for anti-CD40 Antibody (ABIN2662062) Images
Purification The solution is free of unconjugated FITC.
Clone HM40-3
Isotype IgM kappa, IgM

Target Details CD40

Product Details anti-CD40 Antibody Application Details Handling References for anti-CD40 Antibody (ABIN2662062) Images back to top
Antigen
Alternative Name CD40 (CD40 Antibody Abstract)
Background CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39) expressed on activated T cells, is important in costimulation and immune regulation. The HM40-3 antibody has been reported to stimulate dendritic and B cell proliferation and block CD40-CD40L interactions.
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling

Application Details

Product Details anti-CD40 Antibody Target Details CD40 Handling References for anti-CD40 Antibody (ABIN2662062) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-CD40 Antibody Target Details CD40 Application Details References for anti-CD40 Antibody (ABIN2662062) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-CD40 Antibody (ABIN2662062)

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling Images back to top
Background publications

Ma, Xu, An, Dong, Lin, Shi, Wu: "Vaccine with beta-defensin 2-transduced leukemic cells activates innate and adaptive immunity to elicit potent antileukemia responses." in: Cancer research, Vol. 66, Issue 2, pp. 1169-76, 2006

Yu, Siegel, Roeder: "Interaction of the B cell-specific transcriptional coactivator OCA-B and galectin-1 and a possible role in regulating BCR-mediated B cell proliferation." in: The Journal of biological chemistry, Vol. 281, Issue 22, pp. 15505-16, 2006

Morelli, OConnell, Khanna, Logar, Lu, Thomson: "Preferential induction of Th1 responses by functionally mature hepatic (CD8alpha- and CD8alpha+) dendritic cells: association with conversion from liver transplant tolerance to acute rejection." in: Transplantation, Vol. 69, Issue 12, pp. 2647-57, 2000

Akiba, Oshima, Takeda, Atsuta, Nakano, Nakajima, Nohara, Yagita, Okumura: "CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 7058-66, 1999

Ridge, Di Rosa, Matzinger: "A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell." in: Nature, Vol. 393, Issue 6684, pp. 474-8, 1998

Kawano, Cui, Koezuka, Toura, Kaneko, Motoki, Ueno, Nakagawa, Sato, Kondo, Koseki, Taniguchi: "CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides." in: Science (New York, N.Y.), Vol. 278, Issue 5343, pp. 1626-9, 1997

Kaneko, Hirose, Abe, Yagita, Okumura, Shirai: "CD40-mediated stimulation of B1 and B2 cells: implication in autoantibody production in murine lupus." in: European journal of immunology, Vol. 26, Issue 12, pp. 3061-5, 1997

Kashiwada, Kaneko, Yagita, Okumura, Takemori: "Activation of mitogen-activated protein kinases via CD40 is distinct from that stimulated by surface IgM on B cells." in: European journal of immunology, Vol. 26, Issue 7, pp. 1451-8, 1996

Inaba, Inaba, Fukuba, Mori, Haruna, Doi, Adachi, Iwai, Hosaka, Hisha: "Activation of thymic B cells by signals of CD40 molecules plus interleukin-10." in: European journal of immunology, Vol. 25, Issue 5, pp. 1244-8, 1995

Banchereau, Bazan, Blanchard, Brière, Galizzi, van Kooten, Liu, Rousset, Saeland: "The CD40 antigen and its ligand." in: Annual review of immunology, Vol. 12, pp. 881-922, 1994

Clark, Ledbetter: "Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 12, pp. 4494-8, 1986

Images

Product Details anti-CD40 Antibody Target Details CD40 Application Details Handling References for anti-CD40 Antibody (ABIN2662062) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5)  (FITC) (ABIN2662062) anti-CD40 Molecule, TNF Receptor Superfamily Member 5 (CD40) antibody (FITC)