anti-Baboon CD40 Ligand antibody for Flow Cytometry

Recommended CD40 Ligand Antibody (supplied by: Log in to see )

Antigen
CD40 Ligand (CD40LG) Antibodies
  • CD154
  • cd40l
  • CD40L
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TNFSF5
  • TRAP
  • gp39
  • hCD40L
  • CD40-L
  • Cd40l
  • Ly-62
  • Ly62
  • Tnfsf5
  • CD40 ligand
  • TNF superfamily member 5
  • CD40LG
  • cd40l
  • Cd40lg
  • LOC100358388
  • CD154
Reactivity
Baboon, Cynomolgus, Human, Rhesus Monkey
480
242
55
20
20
10
7
7
6
5
4
3
3
3
3
2
1
1
Host
Mouse
291
175
111
51
35
26
2
1
Clonality
Monoclonal
Conjugate
This CD40 Ligand antibody is un-conjugated
75
60
44
15
15
13
13
11
9
9
9
9
9
9
9
8
8
6
6
5
5
5
4
4
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS)
410
295
173
107
68
64
51
42
34
20
16
13
13
11
9
9
6
5
4
4
2
2
2
1
1
1
1
1
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Catalog No. ABIN1177324
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2688992 FACS Mouse IgG1, kappa Log in to see TRAP1 4

General

Antigen CD40 Ligand (CD40LG) Antibodies
Reactivity Baboon, Cynomolgus, Human, Rhesus Monkey
(480), (242), (55), (20), (20), (10), (7), (7), (6), (5), (4), (3), (3), (3), (3), (2), (1), (1)
Host Mouse
(291), (175), (111), (51), (35), (26), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD40 Ligand antibody is un-conjugated
(75), (60), (44), (15), (15), (13), (13), (11), (9), (9), (9), (9), (9), (9), (9), (8), (8), (6), (6), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Flow Cytometry (FACS)
(410), (295), (173), (107), (68), (64), (51), (42), (34), (20), (16), (13), (13), (11), (9), (9), (6), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-CD40 Ligand Antibody

Target Details CD40 Ligand Application Details Handling References for anti-CD40 Ligand antibody (ABIN1177324) Images
Brand BD Pharmingen™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Clone TRAP1
Isotype IgG1, kappa

Target Details CD40 Ligand

Product Details anti-CD40 Ligand Antibody Application Details Handling References for anti-CD40 Ligand antibody (ABIN1177324) Images back to top
Antigen
Alternative Name CD154 (CD40LG Antibody Abstract)
Background Reacts with CD40 ligand (CD40L), a 39 kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells. In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L.
Synonyms: CD40L
Research Area Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Handling References for anti-CD40 Ligand antibody (ABIN1177324) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details References for anti-CD40 Ligand antibody (ABIN1177324) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative Azide free
Storage 4 °C
Storage Comment Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-CD40 Ligand antibody (ABIN1177324)

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details Handling Images back to top
Product cited in:

Fuleihan, Ramesh, Horner, Ahern, Belshaw, Alberg, Stamenkovic, Harmon, Geha: "Cyclosporin A inhibits CD40 ligand expression in T lymphocytes." in: The Journal of clinical investigation, Vol. 93, Issue 3, pp. 1315-20, 1994

Gray, Dullforce, Jainandunsing: "Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction." in: The Journal of experimental medicine, Vol. 180, Issue 1, pp. 141-55, 1994

Nishioka, Lipsky: "The role of CD40-CD40 ligand interaction in human T cell-B cell collaboration." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 3, pp. 1027-36, 1994

Images

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details Handling References for anti-CD40 Ligand antibody (ABIN1177324) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD40 Ligand (CD40LG) antibody (ABIN1177324) anti-CD40 Ligand (CD40LG) antibody