anti-Human CD40 Ligand antibody for Immunoassay

Recommended CD40 Ligand Antibody (supplied by: Log in to see )

Antigen
CD40 Ligand (CD40LG) Antibodies
  • CD154
  • cd40l
  • CD40L
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TNFSF5
  • TRAP
  • gp39
  • hCD40L
  • CD40-L
  • Cd40l
  • Ly-62
  • Ly62
  • Tnfsf5
  • CD40 ligand
  • TNF superfamily member 5
  • CD40LG
  • cd40l
  • Cd40lg
  • LOC100358388
  • CD154
Reactivity
Human
459
236
55
20
20
10
8
8
6
5
4
3
3
3
3
2
2
1
Host
Mouse
275
170
108
51
35
26
2
1
Clonality
Monoclonal
Conjugate
This CD40 Ligand antibody is un-conjugated
73
59
44
14
14
12
12
11
9
8
8
8
8
8
8
6
6
6
6
5
5
5
4
4
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunoassay (IA), Flow Cytometry (FACS), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
405
274
171
93
67
51
50
43
34
20
15
13
11
9
9
7
6
5
4
3
3
2
2
2
1
1
1
1
1
Options
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Catalog No. ABIN2192075
$ 455.24
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2136596 IA ELISA WB Mouse IgG1 Log in to see M18612CL1
1 ABIN2136597 IA ELISA WB Mouse IgG1 Log in to see M18612CL2
1 ABIN2136598 IA ELISA WB Mouse IgG1 Log in to see M18612L3

Top referenced anti-CD40 Ligand antibody for Immunoassay

Similar anti-CD40 Ligand Antibodies

Application / Reactivity Human
Biochemical Assay (BCA) 2 Antibodies
Blocking Antibody (Inhibition) 5 Antibodies
Blocking Peptide (BP) 4 Antibodies
Blocking Reagent (BR) 6 Antibodies
Cytometry by Time of Flight (CyTOF) 3 Antibodies
ELISA 150 Antibodies
ELISA (Capture) 4 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 234 Antibodies
Functional Studies (Func) 27 Antibodies
Immunoassay (IA) 4 Antibodies
Immunocytochemistry (ICC) 18 Antibodies
Immunofluorescence (IF) 17 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 10 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 50 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies

General

Antigen CD40 Ligand (CD40LG) Antibodies
Reactivity Human
(459), (236), (55), (20), (20), (10), (8), (8), (6), (5), (4), (3), (3), (3), (3), (2), (2), (1)
Host Mouse
(275), (170), (108), (51), (35), (26), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD40 Ligand antibody is un-conjugated
(73), (59), (44), (14), (14), (12), (12), (11), (9), (8), (8), (8), (8), (8), (8), (6), (6), (6), (6), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunoassay (IA), Flow Cytometry (FACS), Immunoprecipitation (IP), Neutralization (Neut), Western Blotting (WB)
(405), (274), (171), (93), (67), (51), (50), (43), (34), (20), (15), (13), (11), (9), (9), (7), (6), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-CD40 Ligand Antibody

Target Details CD40 Ligand Application Details Handling ProductDetails: References for anti-CD40 Ligand antibody (ABIN2192075) Images
Sterility 0.2 μm filtered
Clone 24-31

Target Details CD40 Ligand

Product Details anti-CD40 Ligand Antibody Application Details Handling ProductDetails: References for anti-CD40 Ligand antibody (ABIN2192075) Images back to top
Antigen
Alternative Name CD40 Ligand (CD40LG Antibody Abstract)
Background The monoclonal antibody 24-31 recognizes human CD40 ligand (CD40L), also referred as CD154. + CD40L is a transmembrane cell surface glycoprotein of 39 kDa expressed mainly on CD4 T cells and + platelets in an activation-dependent manner. The interaction of CD40L on activated CD4 T cells with CD40 on antigen presenting cells is essential for the T-cell-dependent humoral immune respons. It has a role in T cell-dependent B-cell proliferation, differentiation and memory cell formation. Blocking of the CD40-CD40L interaction results in immunoglobulin isotype switch. Defects in CD40L are the cause of X- linked immunodeficiency with hyper-IgM type Ig which is characterized by elavated concentrations of serum IgMs and decreased amounts of all other types. In vivo, interruption of the CD40 signalling system limits experimental autoimmune diseases such as collagen-induced arthritis, lupus nephritis, rheumatoid arthritis, systemic lupus erythematosus (SLE) and acute or chronic graft-versus-host disease. CD40/CD40L is involved in angiogenic processes. In this process activated platelets are the source of CD40L for CD40 expressed by endothelial cells. The monoclonal antibody 24-31 cross reacts with cynomolgus CD40 ligand. Aliases CD40L, CD40LG, CD154, Gp39, TRAP, TNFSF5
Pathways NF-kappaB Signaling, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Handling ProductDetails: References for anti-CD40 Ligand antibody (ABIN2192075) Images back to top
Application Notes For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For neutralization of biological activity in vitro dilutions have to be made according to the amounts of human CD40L/CD154.
Restrictions For Research Use only

Handling

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details ProductDetails: References for anti-CD40 Ligand antibody (ABIN2192075) Images back to top
Buffer PBS, containing 0.1 % bovine serum albumin.
Storage 4 °C
Storage Comment Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Expiry Date 12 months

ProductDetails: References for anti-CD40 Ligand antibody (ABIN2192075)

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details Handling Images back to top
Product cited in:

Nakamura, Tanaka, Satoh, Kawai, Hirakata, Kaburaki, Kawakami, Ikeda, Kuwana: "Autoantibody to CD40 ligand in systemic lupus erythematosus: association with thrombocytopenia but not thromboembolism." in: Rheumatology (Oxford, England), Vol. 45, Issue 2, pp. 150-6, 2006

Kissel, Berber, Nockher, Santoso, Bein, Hackstein: "Human platelets target dendritic cell differentiation and production of proinflammatory cytokines." in: Transfusion, Vol. 46, Issue 5, pp. 818-27, 2006