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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)|
|Cytometry by Time of Flight (CyTOF)||3 Antibodies||3 Antibodies|
|Western Blotting (WB)||230 Antibodies||31 Antibodies||24 Antibodies|
|Protein Assay (PrA)||1 Antibodies|
|Neutralization (Neut)||6 Antibodies||5 Antibodies|
|Multiplex Assay (MA)||1 Antibodies|
|Mass Cytometry (CyTOF)||3 Antibodies|
|Luminex Assay (LMNX)||2 Antibodies|
|In vivo Studies (in vivo)||2 Antibodies|
|In vitro Assay (in vitro)||1 Antibodies|
|Immunoprecipitation (IP)||47 Antibodies||9 Antibodies||2 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||30 Antibodies||25 Antibodies||8 Antibodies|
|Immunohistochemistry (IHC)||43 Antibodies|
|Antigen||CD40 Ligand (CD40LG) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This CD40 Ligand antibody is un-conjugated Alternatives|
Western Blotting (WB)
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Product Details anti-CD40 Ligand AntibodyTarget Details CD40 Ligand Application Details Handling Images
|Blocking Peptide||Blocking peptide for this product available: ABIN412677|
|Immunogen||Synthetic peptide surrounding amino acid 246 of human CD40 Ligand|
Target Details CD40 LigandProduct Details anti-CD40 Ligand Antibody Application Details Handling Images back to top
|Alternative Name||CD40L (CD40LG Antibody Abstract)|
CD40, also known as bp50 or CDW40, is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L), a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center throμgh interaction with T cells expressing CD40L, and activation of CD4+ T cells. Ligation of CD40 with its ligand preferentially induces stress-activated protein kinases in B lymphocytes.
Synonyms: CD40LG, CD154, TRAP , gp39 , # CD40L , IMD3 , IGM , hCD40L, TNFSF5. HIGM1, CD40-L
|Research Area||Immunology, Adaptive Immunity, Atherosclerosis, Innate Immunity, Cytokines, CD Antigens, Surface Receptors of Immune Cells|
Application DetailsProduct Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Handling Images back to top
Western blot analysis (0.5-4 μg/mL).
Jurkat cell lysate can be used as a positive control.
However, the optimal conditions should be determined individually.
Country of Animal Origin: China
|Restrictions||For Research Use only|
HandlingProduct Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details Images back to top
|Buffer||100 μg (0.5 mg/mL) affinity purified rabbit anti-CD40L polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.|
|Precaution of Use||This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
|Storage Comment||For long-term storage, aliquot and freeze at -70 °C.|
|Expiry Date||12 months|
ImagesProduct Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details Handling back to top