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anti-Human EGFR antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • 9030024J15Rik
  • AI552599
  • C-erb
  • c-erbB
  • CG10079
  • D-Egf
  • d-egf-r
  • D-EGFR
  • Degfr
  • dEgfr
  • DEgfr
  • DEGFR
  • dEGFR
  • dEGFR1
  • der
  • DER
  • Der
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DER flb
  • Dmel\\CG10079
  • DmHD-33
  • EFG-R
  • Egf
  • EGF-R
  • Egf-r
  • EgfR
  • EGfr
  • EGFr
  • EGFR
  • egfr
  • egfr1
  • EGFR12
  • EGFR15
  • EK2-6
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • ERBB
  • Erbb
  • ErbB-1
  • ERBB1
  • Erbb2
  • Errb1
  • Errp
  • flb
  • HD-33
  • HER1
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57Ea
  • l(2)57EFa
  • mENA
  • mor1
  • PIG61
  • TOP
  • top
  • top/DER
  • top/flb
  • Torpedo/DER
  • Torpedo/Egfr
  • torpedo/Egfr
  • torpedo/egfr
  • wa-2
  • wa2
  • Wa5
Epitope
AA 975-1015
146
139
58
57
53
51
51
48
46
45
44
44
35
33
32
30
30
25
24
23
23
23
23
22
21
19
18
17
16
14
14
13
13
13
13
13
13
13
13
12
11
10
10
10
9
9
8
8
8
8
8
8
7
7
6
6
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2156
746
608
23
14
14
13
10
8
5
4
2
1
1
1
1
1
Host
Rabbit
1372
692
63
45
4
2
Clonality
Polyclonal
Conjugate
This EGFR antibody is un-conjugated
93
74
64
55
45
43
25
24
23
21
21
21
21
21
21
21
20
19
19
19
19
19
19
19
19
19
19
2
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
1321
572
514
446
421
245
231
184
87
74
71
55
25
11
11
8
6
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN725720
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087732275 ABIN895013 IF (p) Alexa Fluor 647 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN895015 IF (p) Alexa Fluor 488 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN895012 IF (p) Alexa Fluor 555 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN895017 IF (p) Alexa Fluor 350 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN725723 IF (p) Cy3 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN725725 IF (p) Cy5.5 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN725727 IF (p) FITC Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN725724 IF (p) Cy5 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN725726 IF (p) Cy7 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN2812702 IF (p) Alexa Fluor 594 Rabbit IgG AA 975-1015 Log in to see Polyclonal
0.00087732275 ABIN684196 IF (p) Cy3 Rabbit IgG pSer991 Log in to see Polyclonal
0.00087732275 ABIN684197 IF (p) Cy5 Rabbit IgG pSer991 Log in to see Polyclonal
0.00087732275 ABIN684199 IF (p) Cy7 Rabbit IgG pSer991 Log in to see Polyclonal
0.00087732275 ABIN684200 IF (p) FITC Rabbit IgG pSer991 Log in to see Polyclonal
0.00087732275 ABIN684229 IF (p) Cy7 Rabbit IgG pSer1045 Log in to see Polyclonal
0.00087732275 ABIN684226 IF (p) Cy3 Rabbit IgG pSer1045 Log in to see Polyclonal
0.00087732275 ABIN684228 IF (p) Cy5.5 Rabbit IgG pSer1045 Log in to see Polyclonal
0.00087732275 ABIN684257 IF (p) Cy5 Rabbit IgG pTyr1138 Log in to see Polyclonal
0.00087732275 ABIN684259 IF (p) Cy7 Rabbit IgG pTyr1138 Log in to see Polyclonal
0.00087732275 ABIN684260 IF (p) FITC Rabbit IgG pTyr1138 Log in to see Polyclonal

Similar anti-EGFR Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 1312 Antibodies 481 Antibodies 393 Antibodies
Radioimmunoassay (RIA) 1 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Neutralization (Neut) 11 Antibodies
Luminex Assay (LMNX) 11 Antibodies
Intracellular Staining (ICS) 2 Antibodies 2 Antibodies 2 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Inhibition Assay (InhA) 2 Antibodies
Indirect Immunofluorescence Assay (IFA) 2 Antibodies
Immunostaining (ISt) 1 Antibodies

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope AA 975-1015
(146), (139), (58), (57), (53), (51), (51), (48), (46), (45), (44), (44), (35), (33), (32), (30), (30), (25), (24), (23), (23), (23), (23), (22), (21), (19), (18), (17), (16), (14), (14), (13), (13), (13), (13), (13), (13), (13), (13), (12), (11), (10), (10), (10), (9), (9), (8), (8), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(2156), (746), (608), (23), (14), (14), (13), (10), (8), (5), (4), (2), (1), (1), (1), (1), (1)
Host Rabbit
(1372), (692), (63), (45), (4), (2)
Clonality
Polyclonal
Conjugate This EGFR antibody is un-conjugated
(93), (74), (64), (55), (45), (43), (25), (24), (23), (21), (21), (21), (21), (21), (21), (21), (20), (19), (19), (19), (19), (19), (19), (19), (19), (19), (19), (2), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(1321), (572), (514), (446), (421), (245), (231), (184), (87), (74), (71), (55), (25), (11), (11), (8), (6), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human EGFR
Isotype IgG

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Background

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. Isoform 2 may act as an antagonist of EGF action.

Subcellular location: Cytoplasm


Synonyms: ERBB, HER1, mENA, ERBB1, PIG61, NISBD2, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR
Gene ID 1956
UniProt P00533
Research Area Cancer, Tyrosine Kinases, Growth Factors, Hormones, Receptors
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 975-1015) (ABIN725720) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-EGFR Poly...