anti-Human EGFR antibody for Neutralization

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • C-erb
  • CG10079
  • D-EGFR
  • D-Egf
  • DEGFR
  • DER
  • DER flb
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DEgfr
  • Degfr
  • Der
  • DmHD-33
  • Dmel\\CG10079
  • EFG-R
  • EGF-R
  • EGFR
  • EGFr
  • EGfr
  • EK2-6
  • Egf
  • Egf-r
  • EgfR
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • HD-33
  • TOP
  • Torpedo/DER
  • Torpedo/Egfr
  • c-erbB
  • d-egf-r
  • dEGFR
  • dEGFR1
  • dEgfr
  • der
  • egfr
  • flb
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57EFa
  • l(2)57Ea
  • mor1
  • top
  • top/DER
  • top/flb
  • torpedo/Egfr
  • torpedo/egfr
  • EGFR12
  • EGFR15
  • egfr1
  • Erbb2
  • ERBB
  • ERBB1
  • HER1
  • PIG61
  • mENA
  • ErbB-1
  • Errp
  • 9030024J15Rik
  • AI552599
  • Erbb
  • Errb1
  • Wa5
  • wa-2
  • wa2
  • epidermal growth factor receptor
  • Epidermal growth factor receptor
  • epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • EGFR
  • Egfr
  • egfra
  • egfr1
  • AaeL_AAEL004319
  • LOC100008806
Epitope
AA 1-645
148
122
62
59
57
53
53
51
48
48
48
43
38
36
33
30
29
27
26
25
25
25
23
22
21
19
19
18
17
17
16
16
16
16
15
15
15
15
15
15
14
13
11
9
9
8
7
7
6
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
2334
850
699
29
24
18
17
15
15
6
3
2
2
2
1
1
1
Host
Rabbit
1434
798
67
44
9
3
2
1
1
Antibody Type
Recombinant Antibody
Clonality
Monoclonal
Conjugate
This EGFR antibody is un-conjugated
97
75
66
60
51
49
27
27
26
25
25
24
24
23
23
23
23
23
23
23
21
21
21
21
21
20
19
19
18
2
2
2
1
Application
Neutralization (Neut)
1363
633
572
529
442
272
245
230
111
84
67
56
35
24
19
13
12
11
7
5
4
4
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN5506803
$ 311.85
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5506802 Neut Rabbit IgG AA 1-645 Log in to see RE10
1 ABIN4307247 BP CyTOF FACS IP Neut Mouse IgG2a kappa Extracellular Domain Log in to see B1D8
1 ABIN4307248 BP CyTOF FACS IP Neut Mouse IgG2a kappa Extracellular Domain Log in to see B1D8
1 ABIN4307406 BP CyTOF FACS Neut Rabbit IgG Log in to see C225 (Cetuximab)
1 ABIN4307405 BP CyTOF FACS Neut Rabbit IgG Log in to see C225 (Cetuximab)
1 ABIN4307225 BP CyTOF FACS IP Neut Mouse IgG2a kappa Log in to see GFR450
1 ABIN4307226 BP CyTOF FACS IP Neut Mouse IgG2a kappa Log in to see GFR450
1 ABIN4269132 BP CyTOF FACS Neut WB Rabbit IgG Log in to see Matuzumab
1 ABIN4269131 BP CyTOF FACS Neut WB Rabbit IgG Log in to see Matuzumab
1 ABIN4964929 ELISA Neut Human IgG1 Log in to see
1 ABIN5526184 ELISA Neut Humanized Mouse IgG1 Log in to see
1 ABIN213194 ICC IP IHC Neut WB Mouse IgG1 Log in to see
1 ABIN2261045 IC IP Neut IHC WB Mouse IgG1 Log in to see 0-T-37

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Application / Reactivity Human
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Blocking Reagent (BR) 7 Antibodies
Cell Culture (CC) 1 Antibodies
Cell-ELISA (cELISA) 1 Antibodies
Cellular Assay (CA) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 35 Antibodies
Dot Blot (DB) 84 Antibodies
ELISA 559 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 2 Antibodies
Enzyme Immunoassay (EIA) 56 Antibodies
Flow Cytometry (FACS) 630 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies
Functional Studies (Func) 2 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 19 Antibodies
Immunocytochemistry (ICC) 109 Antibodies

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope AA 1-645
(148), (122), (62), (59), (57), (53), (53), (51), (48), (48), (48), (43), (38), (36), (33), (30), (29), (27), (26), (25), (25), (25), (23), (22), (21), (19), (19), (18), (17), (17), (16), (16), (16), (16), (15), (15), (15), (15), (15), (15), (14), (13), (11), (9), (9), (8), (7), (7), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(2334), (850), (699), (29), (24), (18), (17), (15), (15), (6), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(1434), (798), (67), (44), (9), (3), (2), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EGFR antibody is un-conjugated
(97), (75), (66), (60), (51), (49), (27), (27), (26), (25), (25), (24), (24), (23), (23), (23), (23), (23), (23), (23), (21), (21), (21), (21), (21), (20), (19), (19), (18), (2), (2), (2), (1)
Application Neutralization (Neut)
(1363), (633), (572), (529), (442), (272), (245), (230), (111), (84), (67), (56), (35), (24), (19), (13), (12), (11), (7), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
Specificity Human EGFR / HER1 / ErbB1
Has cross-reactivity with Rhesus EGFR (Catalog # 90317-K08H) in ELISA assay
No cross-reactivity with Mouse EGFR (Catalog # 51091-M08H) and Rat EGFR (Catalog # 80100-R08H) in ELISA assay
Cross-Reactivity Rhesus Monkey
No Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics This antibody was obtained from a rabbit immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1, ABIN2001845 NP_005219, Met1-Ser645, and was produced using recombinant antibody technology.
Endotoxin Level < 3 EU/mg
Immunogen Recombinant Human EGFR / HER1 / ErbB1 Protein (ABIN2001845)
Clone RE01
Isotype IgG

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGFR (EGFR Antibody Abstract)
Research Area Receptors, Growth Factors, Hormones, Cancer, Tyrosine Kinases
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes In a functional ELISA which immobilized the recombinant Human EGF (Catalog # 10605-H01H) at 2 μg/mL (100 μL/well) , 1 μg/mL of the Human EGFR antibody (Catalog # 10001-REN01) can blocked > 50 % the binding of recombinant receptor EGFR (Catalog # 10001-H08H) at 0.08 μg/mL.
The neutralization activity of EGFR Neutralizing Antibody is Measured by its ability to neutralize autocrine EGF induced proliferation in the human breast cancer MDA-MB-468 cell line. The Neutralization titer (IC50) is typically 0.05-0.2 μg/mL for 5000 cells/well.
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in Histidine and Arginine buffer containing 120 mM NaCl, 0.02 % Tween 80, pH 6.0
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling back to top
Supplier Images
 image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (AA 1-645) (ABIN5506803) Cell Proliferation Induced by Autocrine EGF was Neutralized by Human EGFR Antibody. A...