|Application / Reactivity||Human|
|ELISA (Capture)||1 Antibodies|
|Enzyme Immunoassay (EIA)||1 Antibodies|
|Immunocytochemistry (ICC)||1 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||2 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||4 Antibodies|
|Western Blotting (WB)||40 Antibodies|
|Antigen||Growth Hormone 2 (GH2) Antibodies|
|Epitope||N-Term, AA 18-45 Alternatives|
|Conjugate||This Growth Hormone 2 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-Growth Hormone 2 AntibodyTarget Details Growth Hormone 2 Application Details Handling References for anti-Growth Hormone 2 Antibody (ABIN952634) Images
|Specificity||This antibody recognizes Human Growth hormone 2 (N-term).|
|Purification||Protein A column, followed by peptide affinity purification|
|Immunogen||KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human Growth hormone 2 Genename: GH2|
Target Details Growth Hormone 2Product Details anti-Growth Hormone 2 Antibody Application Details Handling References for anti-Growth Hormone 2 Antibody (ABIN952634) Images back to top
|Alternative Name||Growth Hormone 2 (GH2 Antibody Abstract)|
|Background||The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq].Synonyms: GH2, Growth hormone variant, Placenta-specific growth hormone|
|Molecular Weight||25000 Da|
|Pathways||NF-kappaB Signaling, JAK-STAT Signaling|
Application DetailsProduct Details anti-Growth Hormone 2 Antibody Target Details Growth Hormone 2 Handling References for anti-Growth Hormone 2 Antibody (ABIN952634) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-Growth Hormone 2 Antibody Target Details Growth Hormone 2 Application Details References for anti-Growth Hormone 2 Antibody (ABIN952634) Images back to top
|Buffer||PBS containing 0.09 % (W/V) Sodium Azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-Growth Hormone 2 Antibody (ABIN952634)Product Details anti-Growth Hormone 2 Antibody Target Details Growth Hormone 2 Application Details Handling Images back to top
McElholm, McKnight, Patterson et al.: "A population-based study of IGF axis polymorphisms and the esophageal inflammation, metaplasia, adenocarcinoma sequence." in: Gastroenterology, Vol. 139, Issue 1, pp. 204-12.e3, 2010 (PubMed).
de Jesús Romero-Prado, Barrera-Saldaña, Castrillo-Diez: "hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects." in: Gene, Vol. 452, Issue 1, pp. 7-15, 2010 (PubMed).
Christiansen: "Placental growth hormone and growth hormone binding protein are first trimester maternal serum markers of Down syndrome." in: Prenatal diagnosis, Vol. 29, Issue 13, pp. 1249-55, 2009 (PubMed).
Zeck, Widberg, Maylin et al.: "Regulation of placental growth hormone secretion in a human trophoblast model--the effects of hormones and adipokines." in: Pediatric research, Vol. 63, Issue 4, pp. 353-7, 2008 (PubMed).
Mittal, Espinoza, Hassan et al.: "Placental growth hormone is increased in the maternal and fetal serum of patients with preeclampsia." in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, Vol. 20, Issue 9, pp. 651-9, 2007 (PubMed).
ImagesProduct Details anti-Growth Hormone 2 Antibody Target Details Growth Hormone 2 Application Details Handling References for anti-Growth Hormone 2 Antibody (ABIN952634) back to top