The growth hormone receptor (GHR) is the receptor for pituitary gland growth hormone involved in regulating postnatal body growth. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and is a modulator/inhibitor of GH signaling. Binding of GH to the receptor activates the JAK2/STAT5 pathway. Defects in GHR are a cause of Laron dwarfism.
Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4 with 0.09% sodium azide.
Precaution of Use
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.