Browse our anti-IKBKB (IKBKB) Antibodies

Full name:
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta Antibodies (IKBKB)
On www.antibodies-online.com are 681 Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies from 33 different suppliers available. Additionally we are shipping IKBKB Kits (26) and IKBKB Proteins (13) and many more products for this protein. A total of 769 IKBKB products are currently listed.
Synonyms:
AI132552, AIM-1, anon-89Bd, CG4201, DIK, dIKK, dIKK-beta, dIKKbeta, dLak, Dmel\\CG4201, DmIKK, Dmikkb, dmIKKbeta, Ik, IKBKB, ikk, IKK-2, IKK-beta, IKK2, Ikkb, Ikkbeta, IKK[b], ird, Ird-5, Ird5, ird5/DmIkk[beta], Lak, LRK, NFKBIKB
list all antibodies Gene Name GeneID UniProt
IKBKB 3551 O14920
IKBKB 84351 Q9QY78
IKBKB 16150 O88351

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All available anti-IKBKB Antibodies

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Top referenced anti-IKBKB Antibodies

  1. Human Monoclonal IKBKB Primary Antibody for CyTOF, FACS - ABIN252473 : Verma, Stevenson, Schwarz, Van Antwerp, Miyamoto: Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. in Genes & development 1995 (PubMed)
    Show all 57 references for 252473

  2. Human Monoclonal IKBKB Primary Antibody for FACS - ABIN4324267 : Manna, Mukhopadhyay, Aggarwal: Leflunomide suppresses TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2000 (PubMed)
    Show all 37 references for 4324267

  3. Human Monoclonal IKBKB Primary Antibody for IP, WB - ABIN967355 : DiDonato, Hayakawa, Rothwarf, Zandi, Karin: A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. in Nature 1997 (PubMed)
    Show all 12 references for 967355

  4. Human Monoclonal IKBKB Primary Antibody for FACS, GS - ABIN252477 : Vacca, Felli, Palermo, Di Mario, Calce, Di Giovine, Frati, Gulino, Screpanti: Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia. in The EMBO journal 2006 (PubMed)
    Show all 9 references for 252477

  5. Human Monoclonal IKBKB Primary Antibody for WB - ABIN1882049 : Edwards: Anticipation of disaster. in Journal of the Royal Society of Medicine 1991 (PubMed)
    Show all 7 references for 1882049

  6. Human Polyclonal IKBKB Primary Antibody for EIA, WB - ABIN358141 : Tomasoni, Aiello, Cassis, Noris, Longaretti, Cavinato, Azzollini, Pezzotta, Remuzzi, Benigni: Dendritic cells genetically engineered with adenoviral vector encoding dnIKK2 induce the formation of potent CD4+ T-regulatory cells. in Transplantation 2005 (PubMed)
    Show all 5 references for 358141

  7. Human Polyclonal IKBKB Primary Antibody for DB - ABIN1881450 : Yatherajam, Banerjee, McCorkell, Solt, Hanson, Madge, Kang, Worley, Orange, May: Cutting edge: association with I kappa B kinase beta regulates the subcellular localization of Homer3. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for 1881450

  8. Human Polyclonal IKBKB Primary Antibody for DB - ABIN1881453 : Kenneth, Mudie, Rocha: IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function. in The EMBO journal 2010 (PubMed)
    Show all 5 references for 1881453

  9. Cow (Bovine) Polyclonal IKBKB Primary Antibody for WB - ABIN2779400 : Hu, Li, Mahavadi, Murthy: Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle. in The Biochemical journal 2008 (PubMed)

More Antibodies against IKBKB Interaction Partners

Xenopus laevis Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. crystal structure of IKKbeta in complex with an inhibitor, at a resolution of 3.6 A

Human Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. Rare variants in IKBKB are associated with decreased waist-to-hip ratio in European-Americans.

  2. pVHL (show VHL Antibodies) mediates K63-linked ubiquitination of IKKbeta, which plays a role in the regulation of IKK (show CHUK Antibodies)/NF-kappaB (show NFKB1 Antibodies) signalling.

  3. N-acetyl-seryl-aspartyl-lysyl-proline inhibition of TNF-alpha (show TNF Antibodies) activation of canonical, i.e., IKK-beta-dependent, NF-kappaB (show NFKB1 Antibodies) pathway and subsequent decrease in ICAM-1 (show ICAM1 Antibodies) expression is achieved via inhibition of IKK-beta.

  4. our results demonstrate that miR (show MLXIP Antibodies)-200b, a transcriptional target of NF-kappaB (show NFKB1 Antibodies), suppresses breast cancer cell growth and migration, and NF-kappaB (show NFKB1 Antibodies) activation, through downregulation of IKBKB, indicating that miR (show MLXIP Antibodies)-200b has potential as a therapeutic target in breast cancer patients.

  5. The present research concluded that aspirin suppressed prostate cancer cell invasion by reducing MMP-9 (show MMP9 Antibodies) activity and uPA (show PRAP1 Antibodies) expression through decreasing of IKK-beta-mediated NF-kappaB (show NFKB1 Antibodies) activation, indicating that the ability of aspirin to inhibit cell invasion might be useful in the chemoprevention of metastatic prostate cancer.

  6. miR (show MLXIP Antibodies)-429 is involved in regulation of the NF-kappaB (show NFKB1 Antibodies) pathway by targeting IKKbeta and functions as a tumor suppressor in cervical carcinogenesis.

  7. TLR signaling led to lower expression of LRRC14 (show LRRC14 Antibodies).

  8. results uncover a previously unidentified role of IKKbeta in regulating glycolysis, sensing low-glutamine (show GFPT1 Antibodies)-induced metabolic stress, and promoting cellular adaptation to nutrient availability.

  9. data clearly demonstrate that KLHL21 (show KLHL21 Antibodies) negatively regulates TNFalpha (show TNF Antibodies)-activated NF-kappaB (show NFKB1 Antibodies) signaling via targeting IKKbeta, providing new insight into the mechanisms underlying NF-kappaB (show NFKB1 Antibodies) regulation in cells.

  10. Cis (show CISH Antibodies)- and trans-gnetin H suppress cytokine response in LPS (show IRF6 Antibodies)-stimulated THP-1 (show GLI2 Antibodies) cells by preventing activation of key signaling molecules, IKK-beta, IkappaB alpha (show NFKBIA Antibodies), and p65 (show GORASP1 Antibodies), involved in the NF-kappaB (show NFKB1 Antibodies) pathway.

Cow (Bovine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. Staphylococcus aureus infection inhibits nuclear factor kappa B activation mediated by prolactin (show PRL Antibodies) in bovine mammary epithelial cells.

  2. Elevated levels of common free fatty acids found in human serum activate IKKbeta in bovine endothelial cells leading to reduced nitric oxide, and may serve to link pathways involved in inflammation and endothelial dysfunction.

  3. High glucose treatment also activated IKKbeta, and pretreatment with aspirin, a pharmacological inhibitor of IKKbeta, prevented both glucose-induced IKKbeta activation and the effect of high glucose to impair insulin (show INS Antibodies)-mediated NO production.

  4. High glucose-induced IKK (show CHUK Antibodies)-Hsp-90 (show HSP90 Antibodies) interaction contributes to endothelial dysfunction.

Mouse (Murine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. lymphocyte-specific deletion of IKK2 or NEMO (show IKBKG Antibodies) aggravated kidney injury after ischemia-reperfusion injury, and, in both conditions, the percentage of Th17 cells was increased.

  2. data clearly demonstrate that KLHL21 (show KLHL21 Antibodies) negatively regulates TNFalpha (show TNF Antibodies)-activated NF-kappaB (show NFKB1 Antibodies) signaling via targeting IKKbeta, providing new insight into the mechanisms underlying NF-kappaB (show NFKB1 Antibodies) regulation in cells.

  3. Study used three experimental approaches to enhance the IKKbeta activity in the liver of obese mice and observed increased XBP1s activity, reduced endoplasmic reticulum stress, and a significant improvement in insulin (show INS Antibodies) sensitivity and consequently in glucose homeostasis.

  4. Mutation of cysteine 46 in IKK-beta increases inflammatory responses.

  5. TAK1 (show NR2C2 Antibodies) and IKK2 are novel mediators of SCF (show KITLG Antibodies)-induced signaling and potential targets for c-Kit (show KIT Antibodies)-driven diseases.

  6. MyD88s is positively regulated by IKKbeta and CREB (show CREB1 Antibodies) and negatively regulated by ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.

  7. these results highlight an unexpected tumor suppressive function of IKKbeta/NF-kappaB (show NFKB1 Antibodies) in cancer-associated fibroblasts.

  8. These results reveal a hitherto unknown role of mesenchymal IKKbeta in driving inflammation and enabling carcinogenesis in the intestine.

  9. results provide evidence for a previously unrecognized role of IKKbeta in the regulation of the growth plate that is mediated through stimulation-independent downregulation of MCP-5 (show CMA1 Antibodies) in the perichondrium.

  10. IKKbeta was required in both for modification of their hippocampus-dependent appetitive, not consummatory behavior.

IKBKB Antigen Profile

Antigen Summary

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.

Alternative names and synonyms associated with IKBKB

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (ikbkb) antibody
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB) antibody
  • immune response deficient 5 (ird5) antibody
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (Ikbkb) antibody
  • inhibitor of kappaB kinase beta (Ikbkb) antibody
  • AI132552 antibody
  • AIM-1 antibody
  • anon-89Bd antibody
  • CG4201 antibody
  • DIK antibody
  • dIKK antibody
  • dIKK-beta antibody
  • dIKKbeta antibody
  • dLak antibody
  • Dmel\\CG4201 antibody
  • DmIKK antibody
  • Dmikkb antibody
  • dmIKKbeta antibody
  • Ik antibody
  • IKBKB antibody
  • ikk antibody
  • IKK-2 antibody
  • IKK-beta antibody
  • IKK2 antibody
  • Ikkb antibody
  • Ikkbeta antibody
  • IKK[b] antibody
  • ird antibody
  • Ird-5 antibody
  • Ird5 antibody
  • ird5/DmIkk[beta] antibody
  • Lak antibody
  • LRK antibody
  • NFKBIKB antibody

Protein level used designations for IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta , inhibitor of nuclear factor kappa-B kinase subunit beta , inhibitor of nuclear factor kappa-B kinase subunit beta-like , CG4201-PB , IKK-like protein , LPS-responsive kinase , LPS-responsive-kinase , cactus kinase , deficient 5 , immune response , ird5-PB , lipopolysaccharide activated kinase , mmune response deficient 5 , I-kappa-B kinase 2 , I-kappa-B-kinase beta , IKK-B , nuclear factor NF-kappa-B inhibitor kinase beta , IKK-beta , NFKBIKB , inhibitor of kappaB kinase beta , inhibitor of nuclear factor kappa B kinase beta subunit , inhibitor of kappa light chain gene enhancer in B cells, kinase beta , IKK2

GENE ID SPECIES
432200 Xenopus laevis
472749 Pan troglodytes
704683 Macaca mulatta
100142682 Felis catus
100393096 Callithrix jacchus
100440586 Pongo abelii
100471679 Ailuropoda melanoleuca
100551699 Anolis carolinensis
100588081 Nomascus leucogenys
44432 Drosophila melanogaster
3551 Homo sapiens
84351 Rattus norvegicus
482839 Canis lupus familiaris
100101471 Sus scrofa
281854 Bos taurus
426792 Gallus gallus
16150 Mus musculus
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