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Browse our anti-IKBKB (IKBKB) Antibodies

Full name:
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta Antibodies (IKBKB)
On www.antibodies-online.com are 627 Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies from 29 different suppliers available. Additionally we are shipping IKBKB Kits (21) and IKBKB Proteins (10) and many more products for this protein. A total of 707 IKBKB products are currently listed.
Synonyms:
AI132552, AIM-1, anon-89Bd, CG4201, DIK, dIKK, dIKK-beta, dIKKbeta, dLak, Dmel\\CG4201, DmIKK, Dmikkb, dmIKKbeta, Ik, IKBKB, ikk, IKK-2, IKK-beta, IKK2, Ikkb, Ikkbeta, IKK[b], ird, Ird-5, Ird5, ird5/DmIkk[beta], Lak, LRK, NFKBIKB
list all antibodies Gene Name GeneID UniProt
IKBKB 3551 O14920
IKBKB 84351 Q9QY78
IKBKB 16150 O88351

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Top referenced anti-IKBKB Antibodies

  1. Human Monoclonal IKBKB Primary Antibody for IP, WB - ABIN967355 : DiDonato, Hayakawa, Rothwarf, Zandi, Karin: A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. in Nature 1997 (PubMed)
    Show all 12 references for ABIN967355

  2. Human Monoclonal IKBKB Primary Antibody for WB - ABIN1882049 : Edwards: Anticipation of disaster. in Journal of the Royal Society of Medicine 1991 (PubMed)
    Show all 7 references for ABIN1882049

  3. Human Polyclonal IKBKB Primary Antibody for DB - ABIN1881450 : Yatherajam, Banerjee, McCorkell, Solt, Hanson, Madge, Kang, Worley, Orange, May: Cutting edge: association with I kappa B kinase beta regulates the subcellular localization of Homer3. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 5 references for ABIN1881450

  4. Human Polyclonal IKBKB Primary Antibody for EIA, WB - ABIN358141 : Tomasoni, Aiello, Cassis, Noris, Longaretti, Cavinato, Azzollini, Pezzotta, Remuzzi, Benigni: Dendritic cells genetically engineered with adenoviral vector encoding dnIKK2 induce the formation of potent CD4+ T-regulatory cells. in Transplantation 2005 (PubMed)
    Show all 5 references for ABIN358141

  5. Human Polyclonal IKBKB Primary Antibody for DB - ABIN1881453 : Kenneth, Mudie, Rocha: IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function. in The EMBO journal 2010 (PubMed)
    Show all 5 references for ABIN1881453

  6. Human Polyclonal IKBKB Primary Antibody for DB - ABIN1881451 : Zhao, Li, Chen: CC2D1A, a DM14 and C2 domain protein, activates NF-kappaB through the canonical pathway. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881451

  7. Human Polyclonal IKBKB Primary Antibody for EIA, IF - ABIN499972 : Régnier, Song, Gao, Goeddel, Cao, Rothe: Identification and characterization of an IkappaB kinase. in Cell 1997 (PubMed)
    Show all 4 references for ABIN499972

  8. Human Polyclonal IKBKB Primary Antibody for IF - ABIN401636 : Chen, Ryzhakov, Cooray, Randow, Smith: Inhibition of IkappaB kinase by vaccinia virus virulence factor B14. in PLoS pathogens 2008 (PubMed)

  9. Cow (Bovine) Polyclonal IKBKB Primary Antibody for WB - ABIN2779400 : Hu, Li, Mahavadi, Murthy: Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle. in The Biochemical journal 2008 (PubMed)

More Antibodies against IKBKB Interaction Partners

Xenopus laevis Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. crystal structure of IKKbeta in complex with an inhibitor, at a resolution of 3.6 A

Human Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. Combining bortezomib with IKK (show CHUK Antibodies) inhibitor is effective in treating ovarian cancer.

  2. MyD88s is positively regulated by IKKbeta and CREB (show CREB1 Antibodies) and negatively regulated by ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.

  3. IKK-beta suppresses GLI1 (show GLI1 Antibodies) ubiquitination.

  4. we demonstrate that one miR (show MLXIP Antibodies)-497, is a likely negative regulator of IKKbeta

  5. In cells with functional KEAP1 (show KEAP1 Antibodies), RTA (show RBM9 Antibodies) 405 increased NRF2 (show GABPA Antibodies) levels, but not IKKb or BCL2 (show BCL2 Antibodies) levels, and did not increase cell proliferation or survival.

  6. findings indicate that the IKBKB and POLB SNPs confer no genetic predisposition to SLE risk in this Chinese Han population

  7. Demonstrate the essential role of EGFR (show EGFR Antibodies)/Akt (show AKT1 Antibodies)/IkappaBbeta (show NFKBIB Antibodies)/NF-kappaB (show NFKB1 Antibodies) pathway in the inhibitory effect of PA-MSHA on invasion and metastasis of HCC (show FAM126A Antibodies) through suppressing EMT (show ITK Antibodies).

  8. identified IKK-beta as a kinase capable of phosphorylating threonine 3 in N-terminal hungtingtin fragments

  9. The activation of NF-kappaB (show NFKB1 Antibodies) induced translocation of AMAP1 (show ASAP1 Antibodies) to cytoplasm from cell membrane and nucleus, which resulted in augmented interaction of AMAP1 (show ASAP1 Antibodies) and IKKbeta

  10. High IKBKB expression is associated with inflammation in heart Valve Diseases.

Cow (Bovine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. Staphylococcus aureus infection inhibits nuclear factor kappa B activation mediated by prolactin (show PRL Antibodies) in bovine mammary epithelial cells.

  2. Elevated levels of common free fatty acids found in human serum activate IKKbeta in bovine endothelial cells leading to reduced nitric oxide, and may serve to link pathways involved in inflammation and endothelial dysfunction.

  3. High glucose treatment also activated IKKbeta, and pretreatment with aspirin, a pharmacological inhibitor of IKKbeta, prevented both glucose-induced IKKbeta activation and the effect of high glucose to impair insulin (show INS Antibodies)-mediated NO production.

  4. High glucose-induced IKK (show CHUK Antibodies)-Hsp-90 (show HSP90 Antibodies) interaction contributes to endothelial dysfunction.

Mouse (Murine) Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) interaction partners

  1. Mutation of cysteine 46 in IKK-beta increases inflammatory responses.

  2. TAK1 (show NR2C2 Antibodies) and IKK2 are novel mediators of SCF (show KITLG Antibodies)-induced signaling and potential targets for c-Kit (show KIT Antibodies)-driven diseases.

  3. MyD88s is positively regulated by IKKbeta and CREB (show CREB1 Antibodies) and negatively regulated by ERK1/2 (show MAPK1/3 Antibodies) signaling pathways.

  4. these results highlight an unexpected tumor suppressive function of IKKbeta/NF-kappaB (show NFKB1 Antibodies) in cancer-associated fibroblasts.

  5. These results reveal a hitherto unknown role of mesenchymal IKKbeta in driving inflammation and enabling carcinogenesis in the intestine.

  6. results provide evidence for a previously unrecognized role of IKKbeta in the regulation of the growth plate that is mediated through stimulation-independent downregulation of MCP-5 (show CMA1 Antibodies) in the perichondrium.

  7. IKKbeta was required in both for modification of their hippocampus-dependent appetitive, not consummatory behavior.

  8. The role of IKK2 in heart injury induced by ambient fine particulate matter is reported.

  9. In models of diffuse large B-cell lymphoma (DLBCL), the cytotoxicity of LY2409881 (novel inhibitor of IKK2) correlated with the overall activation status of NF-kappaB (show NFKB1 Antibodies).

  10. IKKb activates the expression of proinflammatory mediators, and in adipocytes, IKKb signaling also induces the expression of the anti-inflammatory cytokine IL-13 (show IL13 Antibodies).

IKBKB Antigen Profile

Antigen Summary

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.

Alternative names and synonyms associated with IKBKB

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (ikbkb) antibody
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB) antibody
  • immune response deficient 5 (ird5) antibody
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (Ikbkb) antibody
  • inhibitor of kappaB kinase beta (Ikbkb) antibody
  • AI132552 antibody
  • AIM-1 antibody
  • anon-89Bd antibody
  • CG4201 antibody
  • DIK antibody
  • dIKK antibody
  • dIKK-beta antibody
  • dIKKbeta antibody
  • dLak antibody
  • Dmel\\CG4201 antibody
  • DmIKK antibody
  • Dmikkb antibody
  • dmIKKbeta antibody
  • Ik antibody
  • IKBKB antibody
  • ikk antibody
  • IKK-2 antibody
  • IKK-beta antibody
  • IKK2 antibody
  • Ikkb antibody
  • Ikkbeta antibody
  • IKK[b] antibody
  • ird antibody
  • Ird-5 antibody
  • Ird5 antibody
  • ird5/DmIkk[beta] antibody
  • Lak antibody
  • LRK antibody
  • NFKBIKB antibody

Protein level used designations for IKBKB

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta , inhibitor of nuclear factor kappa-B kinase subunit beta , inhibitor of nuclear factor kappa-B kinase subunit beta-like , CG4201-PB , IKK-like protein , LPS-responsive kinase , LPS-responsive-kinase , cactus kinase , deficient 5 , immune response , ird5-PB , lipopolysaccharide activated kinase , mmune response deficient 5 , I-kappa-B kinase 2 , I-kappa-B-kinase beta , IKK-B , nuclear factor NF-kappa-B inhibitor kinase beta , IKK-beta , NFKBIKB , inhibitor of kappaB kinase beta , inhibitor of nuclear factor kappa B kinase beta subunit , inhibitor of kappa light chain gene enhancer in B cells, kinase beta , IKK2

GENE ID SPECIES
432200 Xenopus laevis
472749 Pan troglodytes
704683 Macaca mulatta
100142682 Felis catus
100393096 Callithrix jacchus
100440586 Pongo abelii
100471679 Ailuropoda melanoleuca
100551699 Anolis carolinensis
100588081 Nomascus leucogenys
44432 Drosophila melanogaster
3551 Homo sapiens
84351 Rattus norvegicus
482839 Canis lupus familiaris
100101471 Sus scrofa
281854 Bos taurus
426792 Gallus gallus
16150 Mus musculus
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