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anti-Human IKBKB antibody for Immunofluorescence

Recommended IKBKB Antibody (supplied by: Log in to see )

Antigen
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
  • AI132552
  • AIM-1
  • anon-89Bd
  • CG4201
  • DIK
  • dIKK
  • dIKK-beta
  • dIKKbeta
  • DLAK
  • dLak
  • Dmel\\CG4201
  • DmIKK
  • Dmikkb
  • DmIKKb
  • DmIkkbeta
  • dmIKKbeta
  • Dmikkbeta
  • DmIKKbeta
  • DmIKKBeta
  • Ik
  • IK
  • IKBKB
  • ikk
  • IKK
  • IKK-2
  • IKK-beta
  • ikk-beta
  • ikk2
  • IKK2
  • Ikkb
  • IKKB
  • IKKb
  • ikkb
  • ikkbeta
  • Ikkbeta
  • IKKbeta
  • IKK[b]
  • ird
  • IRD-5
  • Ird-5
  • Ird5
  • IRD5
  • ird5/DmIkk[beta]
  • Lak
  • LRK
  • NFKBIKB
Epitope
C-Term
49
29
27
21
21
21
20
20
20
20
19
19
19
19
19
19
19
15
15
15
14
9
8
8
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
650
196
131
16
10
2
2
1
1
Host
Rabbit
554
110
9
2
Clonality
Polyclonal
Conjugate
This IKBKB antibody is un-conjugated
38
36
36
33
31
31
10
9
7
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
305
276
264
106
70
63
57
51
39
22
5
5
5
4
3
3
1
1
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Catalog No. ABIN499972
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.2735693 ABIN1882097 IF IHC (p) WB Rabbit Log in to see Polyclonal 8
0.2735693 ABIN2856162 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.2735693 ABIN2707591 IC IF IHC WB Rabbit N-Term, pSer23 Log in to see Polyclonal
0.2735693 ABIN1870261 IF Rabbit IgG pTyr199 Log in to see Polyclonal
0.2735693 ABIN4324266 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
0.2735693 ABIN442231 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.2735693 ABIN2489525 ICC IF IHC (fp) WB Rabbit IgG Log in to see Polyclonal
0.2735693 ABIN516987 IF ELISA WB Mouse IgG2b kappa AA 3-120, partial Log in to see 3C12
0.2735693 ABIN2405048 IF IHC WB Rabbit IgG Log in to see Polyclonal
0.2735693 ABIN3020259 IF Rabbit pTyr199 Log in to see Polyclonal
0.2735693 ABIN4324265 ELISA ICC IF WB Rabbit Log in to see Polyclonal
0.2735693 ABIN3031320 IF IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
0.2735693 ABIN349145 IF Rabbit IgG pTyr199 Log in to see Polyclonal
0.2735693 ABIN349146 IF Rabbit IgG pTyr199 Log in to see Polyclonal
0.2735693 ABIN349358 IF Rabbit IgG Log in to see Polyclonal
0.2735693 ABIN349357 IF Rabbit IgG Log in to see Polyclonal
0.0011096579 ABIN252473 FACS ICC IF IHC IHC (p) IP SimWes WB Mouse IgG1 Log in to see 10AG2 56
0.0011096579 ABIN252477 FACS GS ICC IF IP SimWes WB Mouse IgG1 kappa Log in to see 10A9B6 9
0.0011096579 ABIN401636 IF Rabbit Tyr199 Log in to see Polyclonal 1
0.0011096579 ABIN363020 IF Rabbit IgG AA 197-201 Log in to see Polyclonal 2

Top referenced anti-IKBKB antibody for Immunofluorescence

Similar anti-IKBKB Antibodies

Application / Reactivity Human
Dot Blot (DB) 243 Antibodies
ELISA 290 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 39 Antibodies
Gel Shift (GS) 3 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 21 Antibodies
Immunofluorescence (IF) 52 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 63 Antibodies
Immunohistochemistry (IHC) 106 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 69 Antibodies
Immunoprecipitation (IP) 58 Antibodies
Proximity Ligation Assay (PLA) 6 Antibodies
Simple Western (SimWes) 5 Antibodies
Western Blotting (WB) 274 Antibodies

General

Antigen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
Epitope C-Term
(49), (29), (27), (21), (21), (21), (20), (20), (20), (20), (19), (19), (19), (19), (19), (19), (19), (15), (15), (15), (14), (9), (8), (8), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(650), (196), (131), (16), (10), (2), (2), (1), (1)
Host Rabbit
(554), (110), (9), (2)
Clonality
Polyclonal
Conjugate This IKBKB antibody is un-conjugated
(38), (36), (36), (33), (31), (31), (10), (9), (7), (5), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(305), (276), (264), (106), (70), (63), (57), (51), (39), (22), (5), (5), (5), (4), (3), (3), (1), (1)
Pubmed 4 references available
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Product Details anti-IKBKB Antibody

Target Details IKBKB Application Details Handling References for anti-IKBKB Antibody (ABIN499972) Images
Specificity IKK beta antibody was raised against a peptide corresponding to amino acids near the carboxy-terminus of human IKK beta (Genbank accession NoO14920), which differs from corresponding murine sequence by one amino acid. This polyclonal antibody has no cross response to IKKa or IKKy.
Purification Affinity chromatography purified via peptide column
Immunogen Human IKK beta (C-Terminus 3) Peptide
Isotype IgG

Target Details IKBKB

Product Details anti-IKBKB Antibody Application Details Handling References for anti-IKBKB Antibody (ABIN499972) Images back to top
Antigen
Alternative Name IKBKB / IKKB (IKBKB Antibody Abstract)
Background Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha, and bacteria product LPS. NF-kappaB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity. The long-sought IkappaB kinase (IKK), which phosphorylates IkappaB, and mediates IkappaB degradation and NF-kappaB activation, was recently identified by several laboratories (1-5). IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKalpha and IKKbeta). IKKalpha and IKKbeta interact with each other and both are essential for NF-kappaB activation. IKKbeta phosphorylates both IkappaB-alpha and IkappaB-beta. IKKbeta is expressed in variety of human tissues.Synonyms: I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK-B, IKK-beta, IKK2, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKB, Nuclear factor NF-kappa-B inhibitor kinase beta
Gene ID 3551
UniProt O14920
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-IKBKB Antibody Target Details IKBKB Handling References for anti-IKBKB Antibody (ABIN499972) Images back to top
Application Notes ELISA. Wesern Blot: 1 - 2 μg/mL. A 87 kDa band should be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details References for anti-IKBKB Antibody (ABIN499972) Images back to top
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-IKBKB Antibody (ABIN499972)

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling Images back to top
Background publications

DiDonato, Hayakawa, Rothwarf, Zandi, Karin: "A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB." in: Nature, Vol. 388, Issue 6642, pp. 548-54, 1997

Régnier, Song, Gao, Goeddel, Cao, Rothe: "Identification and characterization of an IkappaB kinase." in: Cell, Vol. 90, Issue 2, pp. 373-83, 1997

Zandi, Rothwarf, Delhase, Hayakawa, Karin: "The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation." in: Cell, Vol. 91, Issue 2, pp. 243-52, 1997

Woronicz, Gao, Cao, Rothe, Goeddel: "IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK." in: Science (New York, N.Y.), Vol. 278, Issue 5339, pp. 866-9, 1997

Images

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling References for anti-IKBKB Antibody (ABIN499972) back to top
Supplier Images
Immunofluorescence (IF) image for anti-IKBKB antibody (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta) (C-Term) (ABIN499972) Immunocytochemistry staining of HeLa cells using AP30406PU-N IKK beta antibody at 10 ...
Western Blotting (WB) image for anti-IKBKB antibody (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta) (C-Term) (ABIN499972) Western blot analysis of IKK beta in Jurkat whole cell lysate with AP30406PU-N IKK be...