anti-Human IKBKB antibody for Immunofluorescence

Recommended IKBKB Antibody (supplied by: Log in to see )

Antigen
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
  • ikk-beta
  • ikk2
  • ikkb
  • ikkbeta
  • IKBKB
  • IKKB
  • CG4201
  • DIK
  • DLAK
  • DmIKK
  • DmIKKBeta
  • DmIKKb
  • DmIKKbeta
  • DmIkkbeta
  • Dmel\\CG4201
  • Dmikkb
  • Dmikkbeta
  • IK
  • IKK
  • IKK-beta
  • IKKb
  • IKKbeta
  • IRD-5
  • IRD5
  • Ik
  • Ikkb
  • Ikkbeta
  • Ird-5
  • Ird5
  • LRK
  • Lak
  • anon-89Bd
  • dIKK
  • dIKK-beta
  • dIKKbeta
  • dLak
  • dmIKKbeta
  • ikk
  • ird
  • ird5/DmIkk[beta]
  • IKK2
  • NFKBIKB
  • AIM-1
  • AI132552
  • IKK-2
  • IKK[b]
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • immune response deficient 5
  • inhibitor of kappaB kinase beta
  • ikbkb
  • IKBKB
  • ird5
  • Ikbkb
Reactivity
Human
688
230
161
22
13
7
7
6
5
4
1
1
Host
Rabbit
581
121
9
2
Clonality
Polyclonal
Conjugate
This IKBKB antibody is un-conjugated
38
37
37
33
31
31
9
7
5
5
5
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
329
305
264
107
80
78
68
43
37
35
6
6
6
5
3
3
2
2
1
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Catalog No. ABIN1882097
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.1781645 ABIN4324266 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 1
11.1781645 ABIN2856162 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
11.1781645 ABIN2707591 IC IF IHC WB Rabbit N-Term, pSer23 Log in to see Polyclonal
11.1781645 ABIN1870261 IF Rabbit IgG pTyr199 Log in to see Polyclonal
11.1781645 ABIN4324265 ELISA ICC IF WB Rabbit Log in to see Polyclonal
11.1781645 ABIN1873179 IF IHC WB Rabbit IgG Log in to see Polyclonal
11.1781645 ABIN442231 ICC IF IHC (p) IHC WB Rabbit IgG C-Term Log in to see Polyclonal
11.1781645 ABIN3031320 IF IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
11.1781645 ABIN516987 IF ELISA WB Mouse IgG2b kappa AA 3-120, partial Log in to see 3C12
11.1781645 ABIN2405048 IF IHC WB Rabbit IgG Log in to see Polyclonal
11.1781645 ABIN3020259 IF Rabbit pTyr199 Log in to see Polyclonal
11.1781645 ABIN349145 IF Rabbit IgG pTyr199 Log in to see Polyclonal
11.1781645 ABIN349146 IF Rabbit IgG pTyr199 Log in to see Polyclonal
11.1781645 ABIN349357 IF Rabbit IgG Log in to see Polyclonal
11.1781645 ABIN349358 IF Rabbit IgG Log in to see Polyclonal
1 ABIN252473 CyTOF FACS ICC IF IHC IHC (p) IP SimWes WB Mouse IgG1 Log in to see 10AG2 57
1 ABIN252477 FACS GS ICC IF IP SimWes WB Mouse IgG1 kappa Log in to see 10A9B6 9
1 ABIN401636 IF Rabbit Tyr199 Log in to see Polyclonal 1
1 ABIN121571 IF WB Rabbit AA 662-680 Log in to see Polyclonal 1
1 ABIN4324294 FACS ICC IF IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 Log in to see 10AG2

General

Antigen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
Reactivity Human
(688), (230), (161), (22), (13), (7), (7), (6), (5), (4), (1), (1)
Host Rabbit
(581), (121), (9), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This IKBKB antibody is un-conjugated
(38), (37), (37), (33), (31), (31), (9), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(329), (305), (264), (107), (80), (78), (68), (43), (37), (35), (6), (6), (6), (5), (3), (3), (2), (2), (1)
Pubmed 8 references available
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Product Details anti-IKBKB Antibody

Target Details IKBKB Application Details Handling ProductDetails: References for anti-IKBKB antibody (ABIN1882097) Images
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This IKK beta antibody is generated from rabbits immunized with recombinant human IKK beta (full length sequence).
Clone RB2161

Target Details IKBKB

Product Details anti-IKBKB Antibody Application Details Handling ProductDetails: References for anti-IKBKB antibody (ABIN1882097) Images back to top
Antigen
Alternative Name IKK beta (IKBKB Antibody Abstract)
Background This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Synonyms: IKBKB, IKKB, Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B kinase 2, Nuclear factor NF-kappa-B inhibitor kinase beta
NCBI Accession NP_001547, NP_001177649, NP_001229707
UniProt O14920
Research Area Immunology, Innate Immunity, Atherosclerosis, Apoptosis/Necrosis, Transcription Factors
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-IKBKB Antibody Target Details IKBKB Handling ProductDetails: References for anti-IKBKB antibody (ABIN1882097) Images back to top
Application Notes WB: 1:1000,IHC (p): 1:50-100,IF: 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details ProductDetails: References for anti-IKBKB antibody (ABIN1882097) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

ProductDetails: References for anti-IKBKB antibody (ABIN1882097)

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling Images back to top
Product cited in:

Le Henaff, Mansouri, Modrowski, Zarka, Geoffroy, Marty, Tarantino, Laplantine, Marie: "Increased NF-?B Activity and Decreased Wnt/?-Catenin Signaling Mediate Reduced Osteoblast Differentiation and Function in ?F508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mice." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 18009-17, 2015

Gouin, Adib-Conquy, Balestrino, Nahori, Villiers, Colland, Dramsi, Dussurget, Cossart: "The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I{kappa}B kinase subunit IKK{alpha}." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 40, pp. 17333-8, 2010

Higashimoto, Chan, Lee, Zandi: "Regulation of I(kappa)B kinase complex by phosphorylation of (gamma)-binding domain of I(kappa)B kinase (beta) by Polo-like kinase 1." in: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35354-67, 2008

Tang, Inohara, Wang, Nuñez, Guan: "Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected]." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38566-70, 2003

Ebner, Bandion, Binder, de Martin, Schmid: "GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta." in: Blood, Vol. 102, Issue 1, pp. 192-9, 2003

Carter, Pennington, Ungurait, Ballard: "In vivo identification of inducible phosphoacceptors in the IKKgamma/NEMO subunit of human IkappaB kinase." in: The Journal of biological chemistry, Vol. 278, Issue 22, pp. 19642-8, 2003

Huang, Chen, Chen: "c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression." in: The Journal of biological chemistry, Vol. 278, Issue 11, pp. 9944-52, 2003

Sakurai, Suzuki, Kawasaki, Nakano, Okazaki, Chino, Doi, Saiki: "Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36916-23, 2003

Images

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling ProductDetails: References for anti-IKBKB antibody (ABIN1882097) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody (ABIN1882097) Western blot analysis of anti-IKK beta Antibody (ABIN1882097) in Hela cell line lysat...
Immunohistochemistry (IHC) image for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody (ABIN1882097) Western blot analysis of anti-IKK beta Antibody (ABIN1882097) in Hela cell line lysat...
Western Blotting (WB) image for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) antibody (ABIN1882097) Western blot analysis of anti-IKK beta Antibody (ABIN1882097) in Hela cell line lysat...