anti-Human IL1A antibody for Western Blotting

Recommended IL1A Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 alpha (IL1A) Antibodies
  • Il-1
  • Il-1a
  • IL-1 alpha
  • IL-1A
  • IL1
  • IL1-ALPHA
  • IL1F1
  • IL-1alpha
  • L1A
  • interleukin 1 complex
  • interleukin 1 alpha
  • interleukin 1, alpha
  • Il1
  • Il1a
  • IL1A
Epitope
N-Term
42
22
13
12
9
7
7
7
6
6
6
5
5
5
5
5
5
4
4
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
291
101
56
10
10
9
8
7
5
5
3
2
2
Host
Rabbit
233
162
34
9
7
7
5
3
3
Clonality
Polyclonal
Conjugate
This IL1A antibody is un-conjugated
67
30
17
13
9
8
4
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
318
282
93
86
59
33
24
24
23
22
19
12
9
9
6
2
2
2
1
1
1
1
1
1
1
1
1
1
Options
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Catalog No. ABIN2785653
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1474795 ABIN390844 WB Rabbit Ig AA 65-94, Ser87 Log in to see Polyclonal 1
3.1474795 ABIN652257 FACS IHC (p) WB Rabbit Ig AA 177-206, Center Log in to see Polyclonal 1
3.1474795 ABIN1724632 ELISA WB Mouse IgG2a Log in to see 3A6F11 2
3.1474795 ABIN1107769 EIA WB Mouse IgG2a Log in to see 1F3B3 2
3.1474795 ABIN1107770 EIA WB Mouse IgG2a Log in to see 1F3B3 2
3.1474795 ABIN453129 EIA WB Rabbit Ser87 Log in to see Polyclonal
3.1474795 ABIN3197694 WB Rabbit Log in to see Polyclonal
3.1474795 ABIN1873200 IHC WB Rabbit IgG Log in to see Polyclonal
3.1474795 ABIN4324351 ICC IF IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
3.1474795 ABIN4324352 IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
3.1474795 ABIN151605 ELISA WB Mouse IgG2a Log in to see 1F3B3
3.1474795 ABIN223536 Neut WB Rabbit IgG Log in to see Polyclonal
3.1474795 ABIN4224395 WB Chicken Log in to see Polyclonal
3.1474795 ABIN4324360 IF IHC IHC (p) WB Mouse IgG1 Log in to see 2F8
3.1474795 ABIN2464070 ELISA WB Mouse IgG2a Log in to see 1F3B3
3.1474795 ABIN2467843 WB Chicken AA 1-271 Log in to see Polyclonal
3.1474795 ABIN5532921 IHC (p) WB Rabbit Ig Fraction AA 474-503, C-Term Log in to see Polyclonal
3.1474795 ABIN1172163 ICC IHC IP WB Rabbit IgG AA 113-271 Log in to see Polyclonal
3.1474795 ABIN4891898 WB Rabbit N-Term Log in to see Polyclonal
3.1474795 ABIN634266 WB Rabbit N-Term Log in to see Polyclonal

General

Antigen Interleukin 1 alpha (IL1A) Antibodies
Epitope N-Term
(42), (22), (13), (12), (9), (7), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Goat, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
(291), (101), (56), (10), (10), (9), (8), (7), (5), (5), (3), (2), (2)
Host Rabbit
(233), (162), (34), (9), (7), (7), (5), (3), (3)
Clonality
Polyclonal
Conjugate This IL1A antibody is un-conjugated
(67), (30), (17), (13), (9), (8), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(318), (282), (93), (86), (59), (33), (24), (24), (23), (22), (19), (12), (9), (9), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL1A Antibody

Target Details IL1A Application Details Handling References for anti-IL1A antibody (ABIN2785653) Images
Blocking Peptide Blocking peptide for this product available: ABIN978484
Sequence VSYGPLHEGC MDQSVSLSIS ETSKTSKLTF KESMVVVATN GKVLKKRRLS
Predicted Reactivity Cow: 92%, Dog: 85%, Goat: 85%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 79%, Sheep: 85%
Characteristics This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IL1A

Target Details IL1A

Product Details anti-IL1A Antibody Application Details Handling References for anti-IL1A antibody (ABIN2785653) Images back to top
Antigen
Alternative Name IL1A (IL1A Antibody Abstract)
Background The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IL-1A, IL1, IL1-ALPHA, IL1F1
Protein Interaction Partner: HFI1, AHC1, GCN5, SPT7, ADA2, NGG1, SPT8, HAX1, NFKBIE, IL1RAP, NDN, S100A13, IL1R2, IL1R1, IL1A, CAPN1,
Protein Size: 271
Molecular Weight 18 kDa
Gene ID 3552
NCBI Accession NM_000575, NP_000566
UniProt P01583
Pathways NF-kappaB Signaling, Autophagy

Application Details

Product Details anti-IL1A Antibody Target Details IL1A Handling References for anti-IL1A antibody (ABIN2785653) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 271 AA

Restrictions For Research Use only

Handling

Product Details anti-IL1A Antibody Target Details IL1A Application Details References for anti-IL1A antibody (ABIN2785653) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-IL1A antibody (ABIN2785653)

Product Details anti-IL1A Antibody Target Details IL1A Application Details Handling Images back to top
Product cited in:

Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: "Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-?B p65 protein." in: Cellular microbiology, Vol. 15, Issue 3, pp. 474-85, 2013

Zheng, Humphry, Maguire, Bennett, Clarke: "Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1?, controlling necrosis-induced sterile inflammation." in: Immunity, Vol. 38, Issue 2, pp. 285-95, 2013

Background publications

Ikeda, Sasazuki, Natsukawa, Shaura, Koizumi, Kasuga, Ohnami, Sakamoto, Yoshida, Iwasaki, Tsugane: "Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population." in: The American journal of gastroenterology, Vol. 103, Issue 6, pp. 1476-87, 2008

Images

Product Details anti-IL1A Antibody Target Details IL1A Application Details Handling References for anti-IL1A antibody (ABIN2785653) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 1 alpha (IL1A) (N-Term) antibody (ABIN2785653) WB Suggested Anti-IL1A Antibody Titration: 0.2-1 ug/ml
Positive Control:...