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Browse our anti-IL1B (IL1B) Antibodies

Full name:
anti-Interleukin 1, beta Antibodies (IL1B)
On www.antibodies-online.com are 796 Interleukin 1, beta (IL1B) Antibodies from 40 different suppliers available. Additionally we are shipping IL1B Kits (233) and IL1B Proteins (205) and many more products for this protein. A total of 1266 IL1B products are currently listed.
Synonyms:
IL-1, IL-1B, IL-1BETA, il1-b, IL1-BETA, IL1B, IL1beta, IL1F2, zgc:111873
list all antibodies Gene Name GeneID UniProt
IL1B 16176 P10749
IL1B 24494  
IL1B 3553 P01584

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Top referenced anti-IL1B Antibodies

  1. Mouse (Murine) Polyclonal IL1B Primary Antibody for Neut, WB - ABIN223538 : Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 6 references for ABIN223538

  2. Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503 : Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011 (PubMed)
    Show all 5 references for ABIN728503

  3. Human Monoclonal IL1B Primary Antibody for ELISA, WB - ABIN395309 : De Iudicibus, Stocco, Martelossi, Londero, Ebner, Pontillo, Lionetti, Barabino, Bartoli, Ventura, Decorti: Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases. in Journal of clinical gastroenterology 2010 (PubMed)
    Show all 5 references for ABIN395309

  4. Human Polyclonal IL1B Primary Antibody for FACS, IHC (p) - ABIN652470 : Ito, Mukaiyama, Itoh, Nagase, Thogersen, Enghild, Sasaguri, Mori: Degradation of interleukin 1beta by matrix metalloproteinases. in The Journal of biological chemistry 1996 (PubMed)
    Show all 3 references for ABIN652470

  5. Dog (Canine) Polyclonal IL1B Primary Antibody for IHC, ELISA - ABIN1582289 : Choi, Lim, Hwang, Lee, Cho, Kim: Anti-ischemic and anti-inflammatory activity of (S)-cis-verbenol. in Free radical research 2010 (PubMed)
    Show all 3 references for ABIN1582289

  6. Human Polyclonal IL1B Primary Antibody for Neut, WB - ABIN223537 : Galmbacher, Heisig, Hotz, Wischhusen, Galmiche, Bergmann, Gentschev, Goebel, Rapp, Fensterle: Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regression. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN223537

  7. Human Monoclonal IL1B Primary Antibody for ICC, IHC - ABIN969215 : Mohideen, Capili, Bilimoria, Yamada, Bonni, Lima: A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 UBC9. in Nature structural & molecular biology 2009 (PubMed)
    Show all 2 references for ABIN969215

  8. Human Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN872644 : Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells. in Molecular and cellular biochemistry 2013 (PubMed)

  9. Human Polyclonal IL1B Primary Antibody for IHC, WB - ABIN2785655 : Piccini, Carta, Tassi, Lasiglié, Fossati, Rubartelli: ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against IL1B Interaction Partners

Zebrafish Interleukin 1, beta (IL1B) interaction partners

  1. Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (show CASP3 Antibodies) dependent manner.

  2. Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.

  3. findings reveal that the Il-1beta-Myd88 (show MYD88 Antibodies) axis and NADPH oxidase (show NOX1 Antibodies)-mediated ROS (show ROS1 Antibodies) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.

  4. the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae

  5. These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.

Mouse (Murine) Interleukin 1, beta (IL1B) interaction partners

  1. Macrophage autophagy functions to limit acute toxin-induced liver injury and death by inhibiting the generation of inflammasome-dependent IL-1beta

  2. this study demonstrates a novel role of HDAC8 (show HDAC8 Antibodies) in LeTx immunotoxicity and regulation of pro-IL-1beta production likely through eRNAs.

  3. These findings thereby provide new mechanistic insight into the regulation of TXNIP (show TXNIP Antibodies) and beta-cell biology and reveal novel links between proinflammatory cytokines, carbohydrate response element binding protein (show MLXIPL Antibodies)-mediated transcription, and microRNA signaling.

  4. In mouse macrophages, uropathogenic Escherichia c (show NLRP3 Antibodies)oli-triggered inflammasome responses are completely NLR (show PLC Antibodies)P3-dependent, triggered IL-1beta secretion, and were largely alpha-hemolysin-dependent.

  5. IL-1beta and IFNgamma upregulate the expression of TRAF2 (show TRAF2 Antibodies) in insulin (show INS Antibodies)-producing INS (show INS Antibodies)-1E cells and isolated rat pancreatic islets.

  6. IL-33 (show IL33 Antibodies) promotes degranulation of bone marrow-derived mast cells and release of cytokines IL-1beta, IL-6 (show IL6 Antibodies) and TNF-alpha (show TNF Antibodies).

  7. Data show taht interleukin 1 beta (IL-1beta) mRNA expression levels were upregulated in white adipose tissues of obese mice and in RAW264.7 macrophages under conditions designed to mimic obese adipose tissue.

  8. studies have uncovered the combined actions of the NLRP3 (show NLRP3 Antibodies) inflammasome and caspase 8 (show CASP8 Antibodies) leading to IL-1beta maturation and the directionality of IL-1beta in driving disease inPstpip2(cmo (show PSTPIP2 Antibodies))mice.

  9. The data reveal that Nlrp3 (show NLRP3 Antibodies) inflammasome-dependent IL-1beta, associated with localized neutrophil recruitment, plays a crucial role in the development of a nonhealing form of cutaneous leishmaniasis in conventionally resistant mice.

  10. IL-1beta increases the level of mRNA encoding xCT (show SLC7A11 Antibodies) in primary cultures of astrocytes isolated from mouse cortex.

Human Interleukin 1, beta (IL1B) interaction partners

  1. Tuberculosis antigen specific IL-1beta may be an additional biomarker for active TB diagnosis among HIV positive subjects.

  2. These results indicate that MF inhibited the production and expression of MMP-1 (show MMP1 Antibodies) and -13 and inflammatory mediators, at least in part, through suppressing the activation of either NF-kappaB (show NFKB1 Antibodies) or p38 MAPK (show MAPK14 Antibodies) in IL-1b-treated SW1353 chondrocytes.

  3. Our study suggests that CC genotype and C allele at -31 and + 3954 polymorphic sites of IL-1beta gene are associated with an increased risk for FMF (show MEFV Antibodies).

  4. Data suggest that production of reactive oxygen species finely tunes vascular endothelial cell function and inflammatory response; mechanisms include pro-inflammatory and pro-oxidant effects of IL1B in up-regulation of production of superoxide anions.

  5. Effect of Short-Term Stimulation with Interleukin-1beta and Differentiation Medium on Human Mesenchymal Stromal Cell Paracrine Activity in Coculture with Osteoblasts.

  6. significant differences were found in carriage rate of both minor alleles of IL-1A (C-889T) and IL-1B (C+3954T) polymorphisms of aggressive periodontitis (AgP) cases compared with healthy controls in the Algerian population; the polymorphisms of the IL-1 genes appear to be associated with susceptibility to AgP in the Algerian population

  7. Our data imply that at sites of tissue damage, when inflammatory mediators are present, for example in lungs of COPD (show ARCN1 Antibodies) patients, MSCs become more potent inducers of repair, in addition to their well-known immune-modulatory properties.

  8. NF-kappaB (show NFKB1 Antibodies) stimulates BMP-2 (show BMP2 Antibodies) mRNA expression in rat and human beta cells upon IL-1b cytokine exposure.

  9. Results indicate that IL-1beta plays an important role in development of uterine luminal epithelium by stimulating cell proliferation, and these effects are coordinately regulated by activation of the ERK1/2 (show MAPK1/3 Antibodies) and P38 MAPK (show MAPK14 Antibodies) cell signaling cascades.

  10. The authors found that cytoplasmic IL-1beta associates with the autophagosome and m-IL-1beta enters into the lumen of a vesicle intermediate but not into the cytoplasmic interior formed by engulfment of the autophagic membrane.

Pig (Porcine) Interleukin 1, beta (IL1B) interaction partners

  1. This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.

  2. local expression of IL-1beta and IL-8 (show IL8 Antibodies) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls

  3. IL1B regulates expression of IL1R1 (show IL1RN Antibodies) and IL1RAP (show IL1RAP Antibodies) and stimulates expression of PTGS1 (show PTGS1 Antibodies) and PTGS2 (show PTGS2 Antibodies) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (show PLIN1 Antibodies)-implantation period of pregnancy in pigs.

  4. the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.

Cow (Bovine) Interleukin 1, beta (IL1B) interaction partners

  1. The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (show IL1RN Antibodies) protein and IL1B and IL1R1 (show IL1RN Antibodies) mRNA were detected.

  2. For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (show P2RX7 Antibodies).

  3. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

  4. Testicular IL-1 alpha (show IL1A Antibodies) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (show IL1A Antibodies) bioactivity and IL-6 (show IL6 Antibodies) concentrations were greatest in the immediate pre-pubertal period.

  5. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.

  6. Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (show PGF Antibodies)(2alpha) and PGE (show LIPF Antibodies)(2) production during luteal phase.

  7. non-metalloproteinase mechanisms participate in IL-1 (show IL1A Antibodies)-induced matrix degradation and loss of tissue material properties

  8. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Antibodies) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Antibodies) signalling pathways

  9. These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (show TNF Antibodies) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.

  10. the low friction of articular cartilage can be modified by TGF-beta1 (show TGFB1 Antibodies) and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness

Rabbit Interleukin 1, beta (IL1B) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (show IL6 Antibodies) in rabbit cornea cells.

  2. IL-1beta and TNF-alpha (show TNF Antibodies) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (show TNF Antibodies).

  3. IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (show SLC2A5 Antibodies) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.

  4. The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.

  5. Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (show TGFB1 Antibodies), which delays the development of osteoarthritis.

  6. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.

  7. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (show COX2 Antibodies), and TGFbeta1 (show TGFB1 Antibodies)

Horse (Equine) Interleukin 1, beta (IL1B) interaction partners

  1. Increased PGE2 production led to reduction in 5-LO (show ALOX5 Antibodies) products in LPS (show IRF6 Antibodies)-treated equine whole blood via IL-1b.

  2. Results suggested that chemokine (show CCL1 Antibodies) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  3. IL-1beta-induced up-regulation of matrix metalloproteinase 13 (show MMP13 Antibodies) mRNA was blocked by all concentrations of geldanamycin tested

  4. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

IL1B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Alternative names and synonyms associated with IL1B

  • interleukin 1, beta (il1b) antibody
  • interleukin 1 beta (Il1b) antibody
  • interleukin 1 beta (IL-1B) antibody
  • interleukin 1, beta (IL1B) antibody
  • IL-1 antibody
  • IL-1B antibody
  • IL-1BETA antibody
  • il1-b antibody
  • IL1-BETA antibody
  • IL1B antibody
  • IL1beta antibody
  • IL1F2 antibody
  • zgc:111873 antibody

Protein level used designations for IL1B

interlukin-1 beta , IL-1 beta , interleukin-1 beta , catabolin , preinterleukin 1 beta , pro-interleukin-1-beta , prointerleukin-1 beta , Interleukin-1 beta , precursor interleukin-1beta , interleukin-1 beta proprotein , interleukin 1 beta , lymphocyte proliferation-potentiating factor , interleukin-beta

GENE ID SPECIES
405770 Danio rerio
16176 Mus musculus
24494 Rattus norvegicus
443539 Ovis aries
100135556 Cavia porcellus
3553 Homo sapiens
397122 Sus scrofa
281251 Bos taurus
100860816 Capra hircus
395196 Gallus gallus
403974 Canis lupus familiaris
100008990 Oryctolagus cuniculus
100034237 Equus caballus
768274 Felis catus
704701 Macaca mulatta
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