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Browse our anti-IL1B (IL1B) Antibodies

Full name:
anti-Interleukin 1, beta Antibodies (IL1B)
On www.antibodies-online.com are 808 Interleukin 1, beta (IL1B) Antibodies from 40 different suppliers available. Additionally we are shipping IL1B Kits (229) and IL1B Proteins (210) and many more products for this protein. A total of 1279 IL1B products are currently listed.
Synonyms:
IL-1, IL-1B, IL-1BETA, il1-b, IL1-BETA, IL1B, IL1beta, IL1F2, zgc:111873
list all antibodies Gene Name GeneID UniProt
IL1B 16176 P10749
IL1B 24494  
IL1B 3553 P01584

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Top referenced anti-IL1B Antibodies

  1. Bacteria Polyclonal IL1B Primary Antibody for ELISA, EM - ABIN269770 : Petrovski, Ayna, Majai, Hodrea, Benko, Mádi, Fésüs: Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages. in Autophagy 2011 (PubMed)
    Show all 9 references for ABIN269770

  2. Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503 : Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011 (PubMed)
    Show all 7 references for ABIN728503

  3. Mouse (Murine) Polyclonal IL1B Primary Antibody for Neut, WB - ABIN223538 : Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 6 references for ABIN223538

  4. Human Monoclonal IL1B Primary Antibody for ELISA, WB - ABIN395309 : De Iudicibus, Stocco, Martelossi, Londero, Ebner, Pontillo, Lionetti, Barabino, Bartoli, Ventura, Decorti: Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases. in Journal of clinical gastroenterology 2010 (PubMed)
    Show all 5 references for ABIN395309

  5. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895764 : Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002 (PubMed)
    Show all 4 references for ABIN4895764

  6. Human Polyclonal IL1B Primary Antibody for FACS, IHC (p) - ABIN652470 : Ito, Mukaiyama, Itoh, Nagase, Thogersen, Enghild, Sasaguri, Mori: Degradation of interleukin 1beta by matrix metalloproteinases. in The Journal of biological chemistry 1996 (PubMed)
    Show all 3 references for ABIN652470

  7. Human Polyclonal IL1B Primary Antibody for Neut, WB - ABIN223537 : Galmbacher, Heisig, Hotz, Wischhusen, Galmiche, Bergmann, Gentschev, Goebel, Rapp, Fensterle: Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regression. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN223537

  8. Human Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN872644 : Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells. in Molecular and cellular biochemistry 2013 (PubMed)

  9. Human Polyclonal IL1B Primary Antibody for IHC, WB - ABIN2785654 : Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein. in Cellular microbiology 2013 (PubMed)

More Antibodies against IL1B Interaction Partners

Zebrafish Interleukin 1, beta (IL1B) interaction partners

  1. Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (show CASP3 Antibodies) dependent manner.

  2. Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.

  3. findings reveal that the Il-1beta-Myd88 (show MYD88 Antibodies) axis and NADPH oxidase (show NOX1 Antibodies)-mediated ROS (show ROS1 Antibodies) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.

  4. the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae

  5. These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.

Mouse (Murine) Interleukin 1, beta (IL1B) interaction partners

  1. It has been demonstrated that beta-endorphin (show POMC Antibodies) stimulates the zymosan-induced secretion of reactive oxygen species and suppresses the spontaneous production of IL-1beta and IL-10 (show IL10 Antibodies) by murine peritoneal macrophages in vivo.

  2. ARTD1 (show PARP1 Antibodies) controls osteoclast development and bone remodelling via its enzymatic activity by modulating the epigenetic marks surrounding the IL-1beta promoter and expression of IL-1beta and subsequently also Nfatc1 (show NFATC1 Antibodies)/A.

  3. The work identifies a pathogenic role of postnatal IL1b/IL-1R1 pathway and subsequent prolonged prominent increase of endocannabinoid signaling in adult seizure susceptibility following prolonged febrile seizures.

  4. This study establishes IL-1beta and IFN-I levels as key homeostatic variables of protective, yet tuned, immune responses against severe invasive bacterial infection.

  5. JNK1 (show MAPK8 Antibodies) mediates pancreatic beta apoptotic cell death associated with increased Myc (show MYC Antibodies) expression in IL1-beta treated cells.

  6. SER140 treatment postpones the onset of diabetes in female NOD mice by interfering with IL-1beta/Il1 (show IL1A Antibodies) receptor signaling.

  7. Sertoli cells have a functional NALP3 (show NLRP3 Antibodies) inflammasome that modulates NOD1 (show NOD1 Antibodies) and pro-IL-1beta expression, while NOD2 (show NOD2 Antibodies) inversely promoted IL-1beta expression.

  8. IL-1beta has the potential to induce bladder remodeling and deteriorate urodynamic parameters in partial bladder outlet obstruction.

  9. Macrophage autophagy functions to limit acute toxin-induced liver injury and death by inhibiting the generation of inflammasome-dependent IL-1beta

  10. this study demonstrates a novel role of HDAC8 (show HDAC8 Antibodies) in LeTx immunotoxicity and regulation of pro-IL-1beta production likely through eRNAs.

Human Interleukin 1, beta (IL1B) interaction partners

  1. In the Chinese population, IL-1beta C+3953T has significant genetic association with an increased risk of spontaneous preterm birth.

  2. The changes observed in the expression of IL-1 (show IL1A Antibodies) and IL-6 (show IL6 Antibodies) seem to exclude their immediate involvement in the progress of B-cell chronic lymphocytic leukaemia.

  3. These results suggest that ROCK may be important in IL-1 (show IL1A Antibodies)-induced signaling through MKK4 (show MAP2K4 Antibodies) to JNK (show MAPK8 Antibodies) and the activation of p38 MAPK (show MAPK14 Antibodies).

  4. This study demonstrated that dysregulated expression of NLRP3 (show NLRP3 Antibodies)-caspase-1 (show CASP1 Antibodies)-IL-1beta axis was observed in patients with MM, suggesting they might be involved in the pathogenesis of MM.

  5. Serum IL-1beta and IL-6 (show IL6 Antibodies) concentrations in the infants who developed perinatal asphyxia were significantly higher compared to values in the normal infants.

  6. The NLRP3 (show NLRP3 Antibodies)/caspase-1 (show CASP1 Antibodies)/IL-1beta axis is active in cartilaginous endplates of patients with Modic changes and inflammatory cascades can exacerbate the cartilaginous endplate degeneration which may act as a trigger for intervertebral disc degeneration and low back pain.

  7. the single nucleotide polymorphisms (SNPs) in IL-1beta-31 might be associated with the gastritis risk, especially in the Caucasian population, while SNPs in the IL-1beta-511 might not be.

  8. Secretion of IL-1beta in the course of Fusobacterium nucleatum infection of gingival epithelial cells.

  9. Taking into account the effects of race, further subgroup analyses were performed and our results showed no association between the IL1B gene -511C/T polymorphism and ischemic stroke (IS) in either Asians or Caucasians. No publication bias was found in our study. In conclusion, the IL1B gene -511C/T polymorphism might not be associated with IS risk.

  10. Data suggest IL1b regulates expression of extracellular matrix proteins (such as MMP1 (show MMP1 Antibodies) and MMP3 (show MMP3 Antibodies)) and proteins involved in cell adhesion (such as ICAM1 (show ICAM1 Antibodies) and VCAM1 (show VCAM1 Antibodies)) in white adipocytes; studies were conducted using differentiated adipocytes (in primary culture) that were obtained from subcutaneous adipose tissue of an obese woman.

Pig (Porcine) Interleukin 1, beta (IL1B) interaction partners

  1. This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.

  2. local expression of IL-1beta and IL-8 (show IL8 Antibodies) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls

  3. IL1B regulates expression of IL1R1 (show IL1RN Antibodies) and IL1RAP (show IL1RAP Antibodies) and stimulates expression of PTGS1 (show PTGS1 Antibodies) and PTGS2 (show PTGS2 Antibodies) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (show PLIN1 Antibodies)-implantation period of pregnancy in pigs.

  4. the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.

Cow (Bovine) Interleukin 1, beta (IL1B) interaction partners

  1. The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (show IL1RN Antibodies) protein and IL1B and IL1R1 (show IL1RN Antibodies) mRNA were detected.

  2. For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (show P2RX7 Antibodies).

  3. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

  4. Testicular IL-1 alpha (show IL1A Antibodies) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (show IL1A Antibodies) bioactivity and IL-6 (show IL6 Antibodies) concentrations were greatest in the immediate pre-pubertal period.

  5. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.

  6. Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (show PGF Antibodies)(2alpha) and PGE (show LIPF Antibodies)(2) production during luteal phase.

  7. non-metalloproteinase mechanisms participate in IL-1 (show IL1A Antibodies)-induced matrix degradation and loss of tissue material properties

  8. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Antibodies) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Antibodies) signalling pathways

  9. These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (show TNF Antibodies) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.

  10. the low friction of articular cartilage can be modified by TGF-beta1 (show TGFB1 Antibodies) and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness

Rabbit Interleukin 1, beta (IL1B) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (show IL6 Antibodies) in rabbit cornea cells.

  2. IL-1beta and TNF-alpha (show TNF Antibodies) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (show TNF Antibodies).

  3. IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (show SLC2A5 Antibodies) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.

  4. The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.

  5. Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (show TGFB1 Antibodies), which delays the development of osteoarthritis.

  6. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.

  7. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (show COX2 Antibodies), and TGFbeta1 (show TGFB1 Antibodies)

Horse (Equine) Interleukin 1, beta (IL1B) interaction partners

  1. Increased PGE2 production led to reduction in 5-LO (show ALOX5 Antibodies) products in LPS (show IRF6 Antibodies)-treated equine whole blood via IL-1b.

  2. Results suggested that chemokine (show CCL1 Antibodies) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  3. IL-1beta-induced up-regulation of matrix metalloproteinase 13 (show MMP13 Antibodies) mRNA was blocked by all concentrations of geldanamycin tested

  4. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

IL1B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Alternative names and synonyms associated with IL1B

  • interleukin 1, beta (il1b) antibody
  • interleukin 1 beta (Il1b) antibody
  • interleukin 1 beta (IL-1B) antibody
  • interleukin 1, beta (IL1B) antibody
  • IL-1 antibody
  • IL-1B antibody
  • IL-1BETA antibody
  • il1-b antibody
  • IL1-BETA antibody
  • IL1B antibody
  • IL1beta antibody
  • IL1F2 antibody
  • zgc:111873 antibody

Protein level used designations for IL1B

interlukin-1 beta , IL-1 beta , interleukin-1 beta , catabolin , preinterleukin 1 beta , pro-interleukin-1-beta , prointerleukin-1 beta , Interleukin-1 beta , precursor interleukin-1beta , interleukin-1 beta proprotein , interleukin 1 beta , lymphocyte proliferation-potentiating factor , interleukin-beta

GENE ID SPECIES
405770 Danio rerio
16176 Mus musculus
24494 Rattus norvegicus
443539 Ovis aries
100135556 Cavia porcellus
3553 Homo sapiens
397122 Sus scrofa
281251 Bos taurus
100860816 Capra hircus
395196 Gallus gallus
403974 Canis lupus familiaris
100008990 Oryctolagus cuniculus
100034237 Equus caballus
768274 Felis catus
704701 Macaca mulatta
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