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Browse our anti-IL1B (IL1B) Antibodies

Full name:
anti-Interleukin 1, beta Antibodies (IL1B)
On www.antibodies-online.com are 789 Interleukin 1, beta (IL1B) Antibodies from 41 different suppliers available. Additionally we are shipping IL1B Kits (265) and IL1B Proteins (199) and many more products for this protein. A total of 1286 IL1B products are currently listed.
Synonyms:
IL-1, IL-1B, IL-1BETA, il1-b, IL1-BETA, IL1B, IL1beta, IL1F2, zgc:111873
list all antibodies Gene Name GeneID UniProt
IL1B 16176 P10749
IL1B 24494  
IL1B 3553 P01584

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Top referenced anti-IL1B Antibodies

  1. Human Monoclonal IL1B Primary Antibody for FACS, ICC - ABIN4899223 : Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000 (PubMed)
    Show all 15 references for ABIN4899223

  2. Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503 : Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011 (PubMed)
    Show all 11 references for ABIN728503

  3. Human Monoclonal IL1B Primary Antibody for ELISA, WB - ABIN395309 : De Iudicibus, Stocco, Martelossi, Londero, Ebner, Pontillo, Lionetti, Barabino, Bartoli, Ventura, Decorti: Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases. in Journal of clinical gastroenterology 2010 (PubMed)
    Show all 5 references for ABIN395309

  4. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895765 : Hussain, Kong, Jordan, Conrad, Madden, Fokt, Priebe, Heimberger: A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. in Cancer research 2007 (PubMed)
    Show all 4 references for ABIN4895765

  5. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895764 : Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002 (PubMed)
    Show all 4 references for ABIN4895764

  6. Human Polyclonal IL1B Primary Antibody for FACS, IHC (p) - ABIN652470 : Ito, Mukaiyama, Itoh, Nagase, Thogersen, Enghild, Sasaguri, Mori: Degradation of interleukin 1beta by matrix metalloproteinases. in The Journal of biological chemistry 1996 (PubMed)
    Show all 3 references for ABIN652470

  7. Human Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN872644 : Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells. in Molecular and cellular biochemistry 2013 (PubMed)
    Show all 2 references for ABIN872644

  8. Dog (Canine) Polyclonal IL1B Primary Antibody for IHC, WB - ABIN5326748 : Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein. in Cellular microbiology 2013 (PubMed)

  9. Human Polyclonal IL1B Primary Antibody for IHC, WB - ABIN2785655 : Piccini, Carta, Tassi, Lasiglié, Fossati, Rubartelli: ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against IL1B Interaction Partners

Zebrafish Interleukin 1, beta (IL1B) interaction partners

  1. Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (show CASP3 Antibodies) dependent manner.

  2. Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.

  3. findings reveal that the Il-1beta-Myd88 (show MYD88 Antibodies) axis and NADPH oxidase (show NOX1 Antibodies)-mediated ROS (show ROS1 Antibodies) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.

  4. the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae

  5. These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.

Mouse (Murine) Interleukin 1, beta (IL1B) interaction partners

  1. this study shows that feeding induces a physiological increase in the number of peritoneal macrophages that secreted IL-1beta, in a glucose-dependent manner

  2. Findings revealed that fluoxetine protects against IL-1beta-induced neuronal apoptosis via p38 (show CRK Antibodies)-p53 (show TP53 Antibodies) dependent pathway, which give us an insight into the potential of fluoxetine in terms of opening up novel therapeutic avenues for neurological diseases including stroke

  3. Il-1 (show IL1A Antibodies) signaling pathway has a key role in abdominal aortic aneurysm formation in mouse model of Kawasaki disease.

  4. Rac2 (show RAC2 Antibodies) to modulates the level of Rac1-dependent macrophage IL-1beta expression, which consequently determines extent of atherosclerotic calcification.

  5. Before the arrival of tumor cells, the lung-recruited monocytic myeloid-derived suppressor cells produced IL-1beta, thereby increasing E-selectin (show SELE Antibodies) expression and promoting tumor cell arrest on endothelial cells.

  6. Study describes a novel pathway for the regulation of hepatic IGFBP1 (show IGFBPI Antibodies) mRNA and protein levels by interleukin (IL)-1beta.

  7. Determined the minimal oligomerization state required for NLRP3 (show NLRP3 Antibodies) inflammasome activation. NLRP3 (show NLRP3 Antibodies) pyrin (show MEFV Antibodies) domain (NLRP3 (show NLRP3 Antibodies)(PYD)) was fused to various dimerization and trimerization domains. Dimerization of the NLRP3 (show NLRP3 Antibodies)(PYD) either in parallel or in antiparallel orientation was insufficient for the inflammasome activation. Trimerization of the NLRP3 (show NLRP3 Antibodies)(PYD) with the foldon domain, however, induced pyroptosis and robust IL-1beta matur...

  8. Pyridoxal 5'-phosphate and pyridoxal reduced IL-1beta production induced by LPS (show TLR4 Antibodies) and ATP, or by LPS (show TLR4 Antibodies) alone, in mice.

  9. Gal-3 (show LGALS3 Antibodies) expression promotes acute colitis and plays an important pro-inflammatory role in the induction phase of colitis by promoting the activation of NLRP3 (show NLRP3 Antibodies) inflammasome and production of IL-1beta in macrophages.

  10. our studies have uncovered a specific role for caspase-1 (show CASP1 Antibodies)-mediated IL-1beta release in the manifestation of Familial Mediterranean Fever (show MEFV Antibodies)

Human Interleukin 1, beta (IL1B) interaction partners

  1. The coincidence of Helicobacter pylori-seropositivity and interleukin-1 polymorphisms was significantly associated with higher levels of high sensitivity C-reactive protein (show CRP Antibodies) and the increased risk of ST-segment elevation myocardial infarction.

  2. The results show that SNP genotype in interleukin 1 beta may be associated with low dose aspirin induced peptic ulcers in this Korean group.

  3. Brazilian sickle cell disease patients with the TNFA (show TNF Antibodies), IL1B, and HLA-DRB1 (show HLA-DRB1 Antibodies) gene polymorphisms were at increased risk of becoming alloimmunized by RBC (show CACNA1C Antibodies) transfusions.

  4. Platelet activity measurements and subsequent interleukin-1beta-dependent activation of the endothelium are increased in subjects with systemic lupus erythematosus.

  5. Rac2 (show RAC2 Antibodies) to modulates the level of Rac1-dependent macrophage IL-1beta expression, which consequently determines extent of atherosclerotic calcification.

  6. Study describes a novel pathway for the regulation of hepatic IGFBP1 (show IGFBPI Antibodies) mRNA and protein levels by interleukin (IL)-1beta.

  7. Vitamin D may enhance autophagy but suppress inflammatory IL-1beta expression in Salmonella-infected intestinal epithelial cells.

  8. present findings suggest that IL-1b T-31C and IL-4 (show IL4 Antibodies) VNTR polymorphisms but not IL-1b C-511T polymorphism may contribute in systemic lupus erythematosus (SLE) pathogenesis. In addition, CT and TT genotypes of IL-1b C-511T polymorphism were associated with SLE.

  9. IL-1beta plays a regulatory role in chronic inflammatory disorders. Therefore, our findings might reveal a compensatory regulatory function of slanDCs during HIV-1 infection

  10. Interleukin-1beta promoter (-511 C/T) polymorphism was not found to be associated with type-II diabetes, the elevated levels of Interleukin-1beta transcripts observed in patients could confer risk towards type-II diabetes.

Pig (Porcine) Interleukin 1, beta (IL1B) interaction partners

  1. This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.

  2. local expression of IL-1beta and IL-8 (show IL8 Antibodies) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls

  3. IL1B regulates expression of IL1R1 (show IL1RN Antibodies) and IL1RAP (show IL1RAP Antibodies) and stimulates expression of PTGS1 (show PTGS1 Antibodies) and PTGS2 (show PTGS2 Antibodies) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (show PLIN1 Antibodies)-implantation period of pregnancy in pigs.

  4. the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.

Cow (Bovine) Interleukin 1, beta (IL1B) interaction partners

  1. The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (show IL1RN Antibodies) protein and IL1B and IL1R1 (show IL1RN Antibodies) mRNA were detected.

  2. For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (show P2RX7 Antibodies).

  3. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

  4. Testicular IL-1 alpha (show IL1A Antibodies) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (show IL1A Antibodies) bioactivity and IL-6 (show IL6 Antibodies) concentrations were greatest in the immediate pre-pubertal period.

  5. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.

  6. Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (show PGF Antibodies)(2alpha) and PGE (show LIPF Antibodies)(2) production during luteal phase.

  7. non-metalloproteinase mechanisms participate in IL-1 (show IL1A Antibodies)-induced matrix degradation and loss of tissue material properties

  8. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Antibodies) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Antibodies) signalling pathways

  9. These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (show TNF Antibodies) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.

  10. the low friction of articular cartilage can be modified by TGF-beta1 (show TGFB1 Antibodies) and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness

Rabbit Interleukin 1, beta (IL1B) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (show IL6 Antibodies) in rabbit cornea cells.

  2. IL-1beta and TNF-alpha (show TNF Antibodies) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (show TNF Antibodies).

  3. IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (show SLC2A5 Antibodies) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.

  4. The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.

  5. Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (show TGFB1 Antibodies), which delays the development of osteoarthritis.

  6. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.

  7. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (show COX2 Antibodies), and TGFbeta1 (show TGFB1 Antibodies)

Horse (Equine) Interleukin 1, beta (IL1B) interaction partners

  1. Increased PGE2 production led to reduction in 5-LO (show ALOX5 Antibodies) products in LPS (show IRF6 Antibodies)-treated equine whole blood via IL-1b.

  2. Results suggested that chemokine (show CCL1 Antibodies) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  3. IL-1beta-induced up-regulation of matrix metalloproteinase 13 (show MMP13 Antibodies) mRNA was blocked by all concentrations of geldanamycin tested

  4. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

IL1B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Alternative names and synonyms associated with IL1B

  • interleukin 1, beta (il1b) antibody
  • interleukin 1 beta (Il1b) antibody
  • interleukin 1 beta (IL-1B) antibody
  • interleukin 1, beta (IL1B) antibody
  • IL-1 antibody
  • IL-1B antibody
  • IL-1BETA antibody
  • il1-b antibody
  • IL1-BETA antibody
  • IL1B antibody
  • IL1beta antibody
  • IL1F2 antibody
  • zgc:111873 antibody

Protein level used designations for IL1B

interlukin-1 beta , IL-1 beta , interleukin-1 beta , catabolin , preinterleukin 1 beta , pro-interleukin-1-beta , prointerleukin-1 beta , Interleukin-1 beta , precursor interleukin-1beta , interleukin-1 beta proprotein , interleukin 1 beta , lymphocyte proliferation-potentiating factor , interleukin-beta

GENE ID SPECIES
405770 Danio rerio
16176 Mus musculus
24494 Rattus norvegicus
443539 Ovis aries
100135556 Cavia porcellus
3553 Homo sapiens
397122 Sus scrofa
281251 Bos taurus
100860816 Capra hircus
395196 Gallus gallus
403974 Canis lupus familiaris
100008990 Oryctolagus cuniculus
100034237 Equus caballus
768274 Felis catus
704701 Macaca mulatta
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