Browse our anti-IL1B (IL1B) Antibodies

Full name:
anti-Interleukin 1, beta Antibodies (IL1B)
On www.antibodies-online.com are 798 Interleukin 1, beta (IL1B) Antibodies from 41 different suppliers available. Additionally we are shipping IL1B Kits (261) and IL1B Proteins (200) and many more products for this protein. A total of 1292 IL1B products are currently listed.
Synonyms:
IL-1, IL-1B, IL-1BETA, il1-b, IL1-BETA, IL1B, IL1beta, IL1F2, zgc:111873
list all antibodies Gene Name GeneID UniProt
IL1B 16176 P10749
IL1B 24494  
IL1B 3553 P01584

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Top referenced anti-IL1B Antibodies

  1. Human Monoclonal IL1B Primary Antibody for FACS, ICC - ABIN4899223 : Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000 (PubMed)
    Show all 15 references for 4899223

  2. Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503 : Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011 (PubMed)
    Show all 11 references for 728503

  3. Human Monoclonal IL1B Primary Antibody for ELISA, WB - ABIN395309 : De Iudicibus, Stocco, Martelossi, Londero, Ebner, Pontillo, Lionetti, Barabino, Bartoli, Ventura, Decorti: Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases. in Journal of clinical gastroenterology 2010 (PubMed)
    Show all 5 references for 395309

  4. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895765 : Hussain, Kong, Jordan, Conrad, Madden, Fokt, Priebe, Heimberger: A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. in Cancer research 2007 (PubMed)
    Show all 4 references for 4895765

  5. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895764 : Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002 (PubMed)
    Show all 4 references for 4895764

  6. Human Polyclonal IL1B Primary Antibody for FACS, IHC (p) - ABIN652470 : Ito, Mukaiyama, Itoh, Nagase, Thogersen, Enghild, Sasaguri, Mori: Degradation of interleukin 1beta by matrix metalloproteinases. in The Journal of biological chemistry 1996 (PubMed)
    Show all 3 references for 652470

  7. Human Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN872644 : Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells. in Molecular and cellular biochemistry 2013 (PubMed)
    Show all 2 references for 872644

  8. Dog (Canine) Polyclonal IL1B Primary Antibody for IHC, WB - ABIN5326748 : Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-κB p65 protein. in Cellular microbiology 2013 (PubMed)

  9. Human Polyclonal IL1B Primary Antibody for IHC, WB - ABIN2785655 : Piccini, Carta, Tassi, Lasiglié, Fossati, Rubartelli: ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against IL1B Interaction Partners

Zebrafish Interleukin 1, beta (IL1B) interaction partners

  1. Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (show CASP3 Antibodies) dependent manner.

  2. Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.

  3. findings reveal that the Il-1beta-Myd88 (show MYD88 Antibodies) axis and NADPH oxidase (show NOX1 Antibodies)-mediated ROS (show ROS1 Antibodies) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.

  4. the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae

  5. These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.

Mouse (Murine) Interleukin 1, beta (IL1B) interaction partners

  1. the data suggest that UA promotes macrophage autophagy and, thereby, suppresses IL-1beta secretion, promotes cholesterol efflux, and attenuates atherosclerosis in mice.

  2. the transient upregulation of IL-1beta and PTPRC/CD45 (show PTPRC Antibodies) during the early phase as well as the increased expression of collagen type I at later stages of repair and validate the differential expression of miR (show MLXIP Antibodies)-204, miR (show MLXIP Antibodies)-205, and miR (show MLXIP Antibodies)-31 in skin wounds.

  3. Irradiation targeting a D2A1 tumor and its microenvironment increased the level of the inflammatory cytokine IL-1beta and was associated with the promotion of cancer cell invasion and lung metastasis development

  4. results indicate that dental calculus stimulates IL-1beta secretion via NLRP3 (show NLRP3 Antibodies) inflammasome in human and mouse phagocytes, and that the crystalline structure has a partial role in the activation of NLRP3 (show NLRP3 Antibodies) inflammasome

  5. NLRP3 inflammasome is decreased and IL-1beta secretion is inhibited in macrophages by hydroxysafflor yellow A and xanthine oxidase

  6. These results strongly suggest that Streptococcus sanguinis has the activity to induce IL-1beta through the NLRP3 (show NLRP3 Antibodies) inflammasome in macrophage and dendritic cell and interaction of purinergic receptors with ATP released is involved in expression of the activity.

  7. these findings highlight a critical role of TSC1 (show TSC1 Antibodies) in regulating innate immunity by control of the mTOR1-C/EBPbeta (show CEBPB Antibodies) pathway.

  8. findings suggest that an IL-1beta-dependent paracrine loop between infiltrated neutrophils/MDMs and ECs drives neuroinflammation.

  9. this study shows that feeding induces a physiological increase in the number of peritoneal macrophages that secreted IL-1beta, in a glucose-dependent manner

  10. Findings revealed that fluoxetine protects against IL-1beta-induced neuronal apoptosis via p38 (show CRK Antibodies)-p53 (show TP53 Antibodies) dependent pathway, which give us an insight into the potential of fluoxetine in terms of opening up novel therapeutic avenues for neurological diseases including stroke

Human Interleukin 1, beta (IL1B) interaction partners

  1. Proteases caspase-1 (show CASP1 Antibodies) and caspase-8 (show CASP8 Antibodies) have redundant roles in cleaving IL-1beta and promoting osteomyelitis. [review]

  2. Inhibition of the inflammatory signaling intermediate p38 MAPK (show MAPK14 Antibodies) reduced tissue factor (show F3 Antibodies) (TF) mRNA by one third but increased tumor necrosis factor (TNF (show TNF Antibodies)) and interleukin-1 beta (IL-1beta) mRNA.

  3. IL-1B-stimulated breast cancer cells down regulate ER-alpha (show ESR1 Antibodies) expression. ER-alpha (show ESR1 Antibodies) promoter methylation is proposed as a regulatory mechanism. Promoter methylation confers resistance to tamoxifen.

  4. These results suggest that common variants in the IL6 (show IL6 Antibodies) and IL1B genes may increase susceptibility for NASH (show SAMSN1 Antibodies) and confer a higher risk of hepatic parenchymal damage including increased ballooning, increased Mallory bodies, and bridging fibrosis or cirrhosis. In contrast, the IL6 (show IL6 Antibodies) rs1800795 C allele may confer a higher risk for steatosis, but less parenchymal damage.

  5. cytokines of the IL-1 (show IL1A Antibodies) family play an important role in homeostatic as well as "emergency" hematopoiesis and are involved in the pathogenesis of several myeloid and lymphoid hematological malignancies.

  6. Results suggest that IL-2 (show IL2 Antibodies)-activated human iNKT cells induce monocytes to produce IL-1beta through a distinctive pathway that does not require the presence of microbial danger signals or alarmins associated with cytopathic damage

  7. Histone deacetylase (show HDAC1 Antibodies) inhibitor vorinostat (SAHA, MK0683) perturb miR (show MLXIP Antibodies)-9-MCPIP1 (show ZC3H12A Antibodies) axis to block IL-1beta-induced IL-6 (show IL6 Antibodies) expression in human OA chondrocytes

  8. results indicate that dental calculus stimulates IL-1beta secretion via NLRP3 (show NLRP3 Antibodies) inflammasome in human and mouse phagocytes, and that the crystalline structure has a partial role in the activation of NLRP3 (show NLRP3 Antibodies) inflammasome

  9. IL-1beta (rs16944) (GG) was associated with reduced risk of influenza A/H3N2 virus infection

  10. Green tea catechins inhibit IL-1beta signaling in rheumatoid arthritis synovial fibroblasts.

Pig (Porcine) Interleukin 1, beta (IL1B) interaction partners

  1. This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.

  2. local expression of IL-1beta and IL-8 (show IL8 Antibodies) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls

  3. IL1B regulates expression of IL1R1 (show IL1RN Antibodies) and IL1RAP (show IL1RAP Antibodies) and stimulates expression of PTGS1 (show PTGS1 Antibodies) and PTGS2 (show PTGS2 Antibodies) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (show PLIN1 Antibodies)-implantation period of pregnancy in pigs.

  4. the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.

Cow (Bovine) Interleukin 1, beta (IL1B) interaction partners

  1. The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (show IL1RN Antibodies) protein and IL1B and IL1R1 (show IL1RN Antibodies) mRNA were detected.

  2. For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (show P2RX7 Antibodies).

  3. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

  4. Testicular IL-1 alpha (show IL1A Antibodies) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (show IL1A Antibodies) bioactivity and IL-6 (show IL6 Antibodies) concentrations were greatest in the immediate pre-pubertal period.

  5. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.

  6. Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (show PGF Antibodies)(2alpha) and PGE (show LIPF Antibodies)(2) production during luteal phase.

  7. non-metalloproteinase mechanisms participate in IL-1 (show IL1A Antibodies)-induced matrix degradation and loss of tissue material properties

  8. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Antibodies) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Antibodies) signalling pathways

  9. These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (show TNF Antibodies) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.

  10. the low friction of articular cartilage can be modified by TGF-beta1 (show TGFB1 Antibodies) and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness

Rabbit Interleukin 1, beta (IL1B) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (show IL6 Antibodies) in rabbit cornea cells.

  2. IL-1beta and TNF-alpha (show TNF Antibodies) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (show TNF Antibodies).

  3. IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (show SLC2A5 Antibodies) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.

  4. The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.

  5. Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (show TGFB1 Antibodies), which delays the development of osteoarthritis.

  6. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.

  7. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (show COX2 Antibodies), and TGFbeta1 (show TGFB1 Antibodies)

Horse (Equine) Interleukin 1, beta (IL1B) interaction partners

  1. Increased PGE2 production led to reduction in 5-LO (show ALOX5 Antibodies) products in LPS (show IRF6 Antibodies)-treated equine whole blood via IL-1b.

  2. Results suggested that chemokine (show CCL1 Antibodies) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  3. IL-1beta-induced up-regulation of matrix metalloproteinase 13 (show MMP13 Antibodies) mRNA was blocked by all concentrations of geldanamycin tested

  4. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

IL1B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Alternative names and synonyms associated with IL1B

  • interleukin 1, beta (il1b) antibody
  • interleukin 1 beta (Il1b) antibody
  • interleukin 1 beta (IL-1B) antibody
  • interleukin 1, beta (IL1B) antibody
  • IL-1 antibody
  • IL-1B antibody
  • IL-1BETA antibody
  • il1-b antibody
  • IL1-BETA antibody
  • IL1B antibody
  • IL1beta antibody
  • IL1F2 antibody
  • zgc:111873 antibody

Protein level used designations for IL1B

interlukin-1 beta , IL-1 beta , interleukin-1 beta , catabolin , preinterleukin 1 beta , pro-interleukin-1-beta , prointerleukin-1 beta , Interleukin-1 beta , precursor interleukin-1beta , interleukin-1 beta proprotein , interleukin 1 beta , lymphocyte proliferation-potentiating factor , interleukin-beta

GENE ID SPECIES
405770 Danio rerio
16176 Mus musculus
24494 Rattus norvegicus
443539 Ovis aries
100135556 Cavia porcellus
3553 Homo sapiens
397122 Sus scrofa
281251 Bos taurus
100860816 Capra hircus
395196 Gallus gallus
403974 Canis lupus familiaris
100008990 Oryctolagus cuniculus
100034237 Equus caballus
768274 Felis catus
704701 Macaca mulatta
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