Browse our anti-IL1B (IL1B) Antibodies

Full name:
anti-Interleukin 1, beta Antibodies (IL1B)
On www.antibodies-online.com are 818 Interleukin 1, beta (IL1B) Antibodies from 41 different suppliers available. Additionally we are shipping IL1B Kits (272) and IL1B Proteins (205) and many more products for this protein. A total of 1328 IL1B products are currently listed.
Synonyms:
IL-1, IL-1B, IL-1BETA, il1-b, IL1-BETA, IL1B, IL1beta, IL1F2, zgc:111873
list all antibodies Gene Name GeneID UniProt
IL1B 16176 P10749
IL1B 24494  
IL1B 3553 P01584

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Top referenced anti-IL1B Antibodies

  1. Human Monoclonal IL1B Primary Antibody for FACS, ICC - ABIN4899223 : Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000 (PubMed)
    Show all 15 references for 4899223

  2. Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503 : Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011 (PubMed)
    Show all 11 references for 728503

  3. Human Monoclonal IL1B Primary Antibody for ELISA, WB - ABIN395309 : De Iudicibus, Stocco, Martelossi, Londero, Ebner, Pontillo, Lionetti, Barabino, Bartoli, Ventura, Decorti: Genetic predictors of glucocorticoid response in pediatric patients with inflammatory bowel diseases. in Journal of clinical gastroenterology 2010 (PubMed)
    Show all 5 references for 395309

  4. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895764 : Hakonarson, Whelan, Leiter, Kim, Chen, Campbell, Grunstein: T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta. in The Journal of allergy and clinical immunology 2002 (PubMed)
    Show all 4 references for 4895764

  5. Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895765 : Hussain, Kong, Jordan, Conrad, Madden, Fokt, Priebe, Heimberger: A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. in Cancer research 2007 (PubMed)
    Show all 4 references for 4895765

  6. Human Polyclonal IL1B Primary Antibody for FACS, IHC (p) - ABIN652470 : Ito, Mukaiyama, Itoh, Nagase, Thogersen, Enghild, Sasaguri, Mori: Degradation of interleukin 1beta by matrix metalloproteinases. in The Journal of biological chemistry 1996 (PubMed)
    Show all 3 references for 652470

  7. Human Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN872644 : Li, Dan, Hu, Ouzhu, Ciren, Wang, Wang, Yang, Ze: CD14 overexpression upregulates TNF-?-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells. in Molecular and cellular biochemistry 2013 (PubMed)
    Show all 2 references for 872644

  8. Dog (Canine) Polyclonal IL1B Primary Antibody for IHC, WB - ABIN5326748 : Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-?B p65 protein. in Cellular microbiology 2013 (PubMed)
    Show all 2 references for 5326748

  9. Human Polyclonal IL1B Primary Antibody for IHC, WB - ABIN2785655 : Piccini, Carta, Tassi, Lasiglié, Fossati, Rubartelli: ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine way. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against IL1B Interaction Partners

Zebrafish Interleukin 1, beta (IL1B) interaction partners

  1. Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (show CASP3 Antibodies) dependent manner.

  2. Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.

  3. findings reveal that the Il-1beta-Myd88 (show MYD88 Antibodies) axis and NADPH oxidase (show NOX1 Antibodies)-mediated ROS (show ROS1 Antibodies) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.

  4. the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae

  5. These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.

Mouse (Murine) Interleukin 1, beta (IL1B) interaction partners

  1. these results implicate IL-1 beta as an important driver of neonatal morbidity in preterm birth

  2. study found that IL-18 (show IL18 Antibodies) and IL-1beta are differentially regulated. Despite being constitutively expressed, IL-18 (show IL18 Antibodies) expression was increased and sustained after stimulation of TLRs. In contrast, IL-1beta was induced but not sustained after chronic treatment.

  3. These findings provide new evidence that IL-27 (show IL27 Antibodies) plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta secretion levels triggered by dual LPS (show TLR4 Antibodies)-ATP stimulation.

  4. inhibiting or silencing multiple cathepsins in macrophages, several key proinflammatory events induced by sterile particles are blocked, including cell death, pro-IL-1beta production, and IL-1beta secretion.

  5. recombinant macrophage migration inhibitory factor (show MIF Antibodies) is important for the synthesis of il1beta mRNA in vivo and in isolated macrophages.

  6. the data suggest that UA promotes macrophage autophagy and, thereby, suppresses IL-1beta secretion, promotes cholesterol efflux, and attenuates atherosclerosis in mice.

  7. the transient upregulation of IL-1beta and PTPRC/CD45 (show PTPRC Antibodies) during the early phase as well as the increased expression of collagen type I at later stages of repair and validate the differential expression of miR (show MLXIP Antibodies)-204, miR (show MLXIP Antibodies)-205, and miR (show MLXIP Antibodies)-31 in skin wounds.

  8. Irradiation targeting a D2A1 tumor and its microenvironment increased the level of the inflammatory cytokine IL-1beta and was associated with the promotion of cancer cell invasion and lung metastasis development

  9. results indicate that dental calculus stimulates IL-1beta secretion via NLRP3 (show NLRP3 Antibodies) inflammasome in human and mouse phagocytes, and that the crystalline structure has a partial role in the activation of NLRP3 (show NLRP3 Antibodies) inflammasome

  10. NLRP3 inflammasome is decreased and IL-1beta secretion is inhibited in macrophages by hydroxysafflor yellow A and xanthine oxidase

Human Interleukin 1, beta (IL1B) interaction partners

  1. The presence of IL1B-31*C allele plus the presence of S. aureus and/or H. influenzae could be related to the development of tonsillitis in this particular Mexican population. Patients with at least one copy of the IL1B-31*C allele had a higher risk of recurrent tonsillitis (OR = 4.03; 95% CI = 1.27-14.27; P = 0.013).

  2. p38 (show CRK Antibodies), c-jun (show JUN Antibodies), and NFkappaB (show NFKB1 Antibodies) pathways activated during intervertebral disc degeneration by IL-1beta but not GDF-5 (show GDF5 Antibodies)

  3. Study showed that alterations in CRHR1 (show CRHR1 Antibodies) gene were associated with higher levels of IL-1beta, and increased risk for suicide, reinforcing the importance of multifactorial interactions of biological markers for psychiatric disorders.

  4. These findings provide new evidence that IL-27 (show IL27 Antibodies) plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta secretion levels triggered by dual LPS (show IRF6 Antibodies)-ATP stimulation.

  5. Cystatin C significantly decreased the lipopolysaccharide-stimulated release and expression of interleukin-1beta in monocyte and peripheral blood mononuclear cultures from healthy donors and Crohn's patients.

  6. IL-1beta Induces NF2 (show NF2 Antibodies) Promoter Methylation in Meningioma/Leptomeningeal Cells.

  7. The results of this study showed that Depression during the acute ACS (show PLA2G15 Antibodies) was significantly associated with the IL-1beta levels and the -511T allele

  8. Our data indicate sustained activation of IL-1 (show IL1A Antibodies) and IL-36 in generalized pustular psoriasis (GPP), inducing neutrophil chemokine (show CCL1 Antibodies) expression, infiltration, and pustule formation, suggesting that the IL-1 (show IL1A Antibodies)/IL-36 inflammatory axis is a potent driver of disease pathology in GPP

  9. Proteases caspase-1 (show CASP1 Antibodies) and caspase-8 (show CASP8 Antibodies) have redundant roles in cleaving IL-1beta and promoting osteomyelitis. [review]

  10. Inhibition of the inflammatory signaling intermediate p38 MAPK (show MAPK14 Antibodies) reduced tissue factor (show F3 Antibodies) (TF) mRNA by one third but increased tumor necrosis factor (TNF (show TNF Antibodies)) and interleukin-1 beta (IL-1beta) mRNA.

Pig (Porcine) Interleukin 1, beta (IL1B) interaction partners

  1. This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.

  2. local expression of IL-1beta and IL-8 (show IL8 Antibodies) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls

  3. IL1B regulates expression of IL1R1 (show IL1RN Antibodies) and IL1RAP (show IL1RAP Antibodies) and stimulates expression of PTGS1 (show PTGS1 Antibodies) and PTGS2 (show PTGS2 Antibodies) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (show PLIN1 Antibodies)-implantation period of pregnancy in pigs.

  4. the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.

Cow (Bovine) Interleukin 1, beta (IL1B) interaction partners

  1. The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (show IL1RN Antibodies) protein and IL1B and IL1R1 (show IL1RN Antibodies) mRNA were detected.

  2. For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (show P2RX7 Antibodies).

  3. Role of TGF-beta1 (show TGFB1 Antibodies) and TNF-alpha (show TNF Antibodies) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.

  4. Testicular IL-1 alpha (show IL1A Antibodies) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (show IL1A Antibodies) bioactivity and IL-6 (show IL6 Antibodies) concentrations were greatest in the immediate pre-pubertal period.

  5. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.

  6. Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (show PGF Antibodies)(2alpha) and PGE (show LIPF Antibodies)(2) production during luteal phase.

  7. non-metalloproteinase mechanisms participate in IL-1 (show IL1A Antibodies)-induced matrix degradation and loss of tissue material properties

  8. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Antibodies) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Antibodies) signalling pathways

  9. These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (show TNF Antibodies) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.

  10. the low friction of articular cartilage can be modified by TGF-beta1 (show TGFB1 Antibodies) and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness

Rabbit Interleukin 1, beta (IL1B) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (show IL6 Antibodies) in rabbit cornea cells.

  2. IL-1beta and TNF-alpha (show TNF Antibodies) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (show TNF Antibodies).

  3. IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (show SLC2A5 Antibodies) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.

  4. The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.

  5. Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (show TGFB1 Antibodies), which delays the development of osteoarthritis.

  6. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.

  7. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (show COX2 Antibodies), and TGFbeta1 (show TGFB1 Antibodies)

Horse (Equine) Interleukin 1, beta (IL1B) interaction partners

  1. Increased PGE2 production led to reduction in 5-LO (show ALOX5 Antibodies) products in LPS (show IRF6 Antibodies)-treated equine whole blood via IL-1b.

  2. Results suggested that chemokine (show CCL1 Antibodies) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  3. IL-1beta-induced up-regulation of matrix metalloproteinase 13 (show MMP13 Antibodies) mRNA was blocked by all concentrations of geldanamycin tested

  4. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Antibodies) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

IL1B Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Alternative names and synonyms associated with IL1B

  • interleukin 1, beta (il1b) antibody
  • interleukin 1 beta (Il1b) antibody
  • interleukin 1 beta (IL-1B) antibody
  • interleukin 1, beta (IL1B) antibody
  • IL-1 antibody
  • IL-1B antibody
  • IL-1BETA antibody
  • il1-b antibody
  • IL1-BETA antibody
  • IL1B antibody
  • IL1beta antibody
  • IL1F2 antibody
  • zgc:111873 antibody

Protein level used designations for IL1B

interlukin-1 beta , IL-1 beta , interleukin-1 beta , catabolin , preinterleukin 1 beta , pro-interleukin-1-beta , prointerleukin-1 beta , Interleukin-1 beta , precursor interleukin-1beta , interleukin-1 beta proprotein , interleukin 1 beta , lymphocyte proliferation-potentiating factor , interleukin-beta

GENE ID SPECIES
405770 Danio rerio
16176 Mus musculus
24494 Rattus norvegicus
443539 Ovis aries
100135556 Cavia porcellus
3553 Homo sapiens
397122 Sus scrofa
281251 Bos taurus
100860816 Capra hircus
395196 Gallus gallus
403974 Canis lupus familiaris
100008990 Oryctolagus cuniculus
100034237 Equus caballus
768274 Felis catus
704701 Macaca mulatta
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