anti-Dog (Canine) IL1B antibody for Neutralization

Recommended IL1B Antibody (supplied by: Log in to see )

Antigen
Interleukin 1, beta (IL1B) Antibodies
  • il1-b
  • zgc:111873
  • IL-1beta
  • Il-1b
  • IL1B
  • IL-1
  • IL1-BETA
  • IL1F2
  • IL-1BETA
  • IL1beta
  • IL-1B
  • interleukin 1, beta
  • interleukin 1 beta
  • il1b
  • Il1b
  • IL-1B
  • IL1B
Epitope
AA 114-265
33
31
30
21
16
15
15
14
12
11
11
7
7
7
6
6
5
5
5
5
4
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine)
531
187
126
37
28
20
16
13
13
12
8
7
6
4
4
2
2
2
1
1
Host
Goat
406
355
16
16
8
7
6
2
2
Clonality
Polyclonal
Conjugate
This IL1B antibody is un-conjugated
96
47
33
24
14
13
12
11
9
9
8
8
8
8
8
8
8
6
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
517
414
175
140
112
72
59
54
44
32
31
24
16
14
14
7
5
4
4
3
3
3
3
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN4899222
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN964768 FACS IP IHC Neut RIA ELISA WB HRP Rabbit IgG N-Term, Cleavage Site Log in to see Polyclonal
1 ABIN964752 FACS IP IHC Neut RIA ELISA WB Rabbit IgG N-Term, Cleavage Site Log in to see Polyclonal
1 ABIN964777 FACS IP IHC Neut RIA ELISA WB Biotin Rabbit IgG N-Term, Cleavage Site Log in to see Polyclonal

General

Antigen Interleukin 1, beta (IL1B) Antibodies
Epitope AA 114-265
(33), (31), (30), (21), (16), (15), (15), (14), (12), (11), (11), (7), (7), (7), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine)
(531), (187), (126), (37), (28), (20), (16), (13), (13), (12), (8), (7), (6), (4), (4), (2), (2), (2), (1), (1)
Host Goat
(406), (355), (16), (16), (8), (7), (6), (2), (2)
Clonality
Polyclonal
Conjugate This IL1B antibody is un-conjugated
(96), (47), (33), (24), (14), (13), (12), (11), (9), (9), (8), (8), (8), (8), (8), (8), (8), (6), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
(517), (414), (175), (140), (112), (72), (59), (54), (44), (32), (31), (24), (16), (14), (14), (7), (5), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL1B Antibody

Target Details IL1B Application Details Handling ProductDetails: References for anti-IL1B antibody (ABIN4899222) Images
Specificity Detects canine IL-1 beta in direct ELISAs and Western blots. In direct ELISAs, approximately 40 % cross-reactivity with recombinant feline IL-1 beta is observed, less than 10 % cross-reactivity with recombinant human IL-1 beta , recombinant rhesus macaque IL-1 beta , recombinant equine IL-1 beta , and recombinant porcine IL-1 beta is observed, less than 5 % cross-reactivity with recombinant mouse (rm) IL-1 beta , recombinant rat IL-1 beta , and recombinant cotton rat (rcr) IL-1 beta is observed, and less than 1 % cross-reactivity with rcrIL-1 alpha , rmIL-1ra, and recombinant canine IL-18 is observed.
Purification Immunogen affinity purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Immunogen E. coli-derived recombinant canine IL-1 beta/IL-1F2, Ala114-Ser265, Accession # ABB73214
Isotype IgG

Target Details IL1B

Product Details anti-IL1B Antibody Application Details Handling ProductDetails: References for anti-IL1B antibody (ABIN4899222) Images back to top
Antigen
Alternative Name IL-1 beta/il-1F2 (IL1B Antibody Abstract)
Background Alternative Names: catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta
Gene ID 3553
Pathways NF-kappaB Signaling, Interferon-gamma Pathway, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy

Application Details

Product Details anti-IL1B Antibody Target Details IL1B Handling ProductDetails: References for anti-IL1B antibody (ABIN4899222) Images back to top
Application Notes Western Blot 0.1 μg/mL
Neutralization 2-10 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL1B Antibody Target Details IL1B Application Details ProductDetails: References for anti-IL1B antibody (ABIN4899222) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

ProductDetails: References for anti-IL1B antibody (ABIN4899222)

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling Images back to top
Product cited in:

Kiczak, Paslawska, Bania, Ugorski, Sambor, Kochman, Blach, Chelmonska-Soyta: "Increased expression of interleukin-1beta and its novel splice variant in canine hearts with volume overload." in: Cytokine, Vol. 44, Issue 3, pp. 352-60, 2008 Method employed by authors: Western Blotting (WB) (Sample species: Dog (Canine)).

Images

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling ProductDetails: References for anti-IL1B antibody (ABIN4899222) back to top
Supplier Images
Neutralization (Neut) image for anti-Interleukin 1, beta (IL1B) (AA 114-265) antibody (ABIN4899222) Cell Proliferation Induced by IL-1 beta/IL-1F2 and Neutral-ization by Canine IL-1 bet...