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anti-Sheep (Ovine) IL1B antibody for Functional Studies

Recommended IL1B Antibody (supplied by: Log in to see )

Antigen
Interleukin 1, beta (IL1B) Antibodies
  • il1-b
  • zgc:111873
  • IL-1beta
  • Il-1b
  • IL1B
  • IL-1
  • IL1-BETA
  • IL1F2
  • IL-1BETA
  • IL1beta
  • IL-1B
  • interleukin 1, beta
  • interleukin 1 beta
  • il1b
  • Il1b
  • IL-1B
  • IL1B
Reactivity
Sheep (Ovine)
533
179
128
38
31
22
18
17
12
11
8
7
7
4
3
2
2
2
1
1
Host
Rabbit
408
351
17
16
8
8
6
3
2
Clonality
Polyclonal
Conjugate
This IL1B antibody is un-conjugated
100
48
35
22
13
12
11
10
8
8
8
8
8
8
8
8
8
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA), Western Blotting (WB)
539
434
176
126
110
74
59
58
38
28
25
23
14
14
13
7
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN318984
$ 467.50
Plus shipping costs $45.00

Top referenced anti-IL1B antibody for Functional Studies

Similar anti-IL1B Antibodies

Application / Reactivity Sheep (Ovine)
ELISA 25 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 6 Antibodies
Functional Studies (Func) 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunohistochemistry (IHC) 4 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 26 Antibodies

General

Antigen Interleukin 1, beta (IL1B) Antibodies
Reactivity Sheep (Ovine)
(533), (179), (128), (38), (31), (22), (18), (17), (12), (11), (8), (7), (7), (4), (3), (2), (2), (2), (1), (1)
Host Rabbit
(408), (351), (17), (16), (8), (8), (6), (3), (2)
Clonality
Polyclonal
Conjugate This IL1B antibody is un-conjugated
(100), (48), (35), (22), (13), (12), (11), (10), (8), (8), (8), (8), (8), (8), (8), (8), (8), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA), Western Blotting (WB)
(539), (434), (176), (126), (110), (74), (59), (58), (38), (28), (25), (23), (14), (14), (13), (7), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL1B Antibody

Target Details IL1B Application Details Handling References for anti-IL1B Antibody (ABIN318984) Images
Specificity This antibody recognizes Interleukin-1 beta (IL-1 beta). No cross-reactivity is seen with ovine IL-6, IL-8, MCP-1 or TNF alpha.
Cross-Reactivity (Details) Species reactivity (expected):Bovine, Goat.
Species reactivity (tested):Sheep.
Purification Serum
Immunogen Recombinant IL-1 beta
Isotype IgG

Target Details IL1B

Product Details anti-IL1B Antibody Application Details Handling References for anti-IL1B Antibody (ABIN318984) Images back to top
Antigen
Alternative Name Interleukin-1 beta / IL-1B (IL1B Antibody Abstract)
Background Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25 % homology in their amino acid sequence.Synonyms: Catabolin, IL-1 beta, IL1 beta, IL1B, IL1F2
Gene ID 443539
NCBI Accession NP_001009465
UniProt P21621
Pathways NF-kappaB Signaling, TCR Signaling, Interferon-gamma Pathway, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity

Application Details

Product Details anti-IL1B Antibody Target Details IL1B Handling References for anti-IL1B Antibody (ABIN318984) Images back to top
Application Notes ELISA: 1/500. Western blot. Functional assay: Neutralises the bioactivity of IL-1 beta. Removal of sodium azide isrecommended prior to use.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IL1B Antibody Target Details IL1B Application Details References for anti-IL1B Antibody (ABIN318984) Images back to top
Format Liquid
Buffer 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

References for anti-IL1B Antibody (ABIN318984)

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling Images back to top
Background publications

Rothel, Hurst, Seow, Pépin, Berthon, Corner, Wood: "Analysis of ovine IL-1 beta production in vivo and in vitro by enzyme immunoassay and immunohistochemistry." in: Veterinary immunology and immunopathology, Vol. 57, Issue 3-4, pp. 267-78, 1997