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Browse our anti-IL1R1 (IL1R1) Antibodies

Full name:
anti-Interleukin 1 Receptor, Type I Antibodies (IL1R1)
On are 215 Interleukin 1 Receptor, Type I (IL1R1) Antibodies from 22 different suppliers available. Additionally we are shipping IL1R1 Proteins (36) and IL1R1 Kits (28) and many more products for this protein. A total of 297 IL1R1 products are currently listed.
CD121a, CD121b, D2S1473, IL-1R-alpha, IL-iR, IL1R, Il1r-1, IL1RA, P80
list all antibodies Gene Name GeneID UniProt
IL1R1 3554 P14778
IL1R1 16177 P13504
IL1R1 25663  

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Most Popular Reactivities for anti-IL1R1 (IL1R1) Antibodies

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anti-Human IL1R1 Antibodies:

anti-Mouse (Murine) IL1R1 Antibodies:

anti-Rat (Rattus) IL1R1 Antibodies:

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Top referenced anti-IL1R1 Antibodies

  1. Human Polyclonal IL1R1 Primary Antibody for FACS - ABIN4898601 : Endo, Blinova, Romantseva, Golding, Zaitseva: Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1β and TRIF/IRF3. in PLoS ONE 2014 (PubMed)
    Show all 5 references for ABIN4898601

  2. Human Polyclonal IL1R1 Primary Antibody for IHC (p), WB - ABIN390328 : Debets, Timans, Homey, Zurawski, Sana, Lo, Wagner, Edwards, Clifford, Menon, Bazan, Kastelein: Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 4 references for ABIN390328

  3. Human Polyclonal IL1R1 Primary Antibody for FACS - ABIN4898597 : Zhang, Cheng, Zhao, Li, Zhang, Chen, Nie, Reszka-Blanco, Wang, Su: Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion. in The Journal of clinical investigation 2015 (PubMed)
    Show all 3 references for ABIN4898597

  4. Human Polyclonal IL1R1 Primary Antibody for ELISA, IP - ABIN1995763 : Vigers, Anderson, Caffes, Brandhuber: Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta. in Nature 1997 (PubMed)

  5. Human Polyclonal IL1R1 Primary Antibody for FACS - ABIN4898595 : Miranda, Funes, Sánchez, Limia, Mesa, Quezada, Pérez, de León: Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure. in Cancer research 2015 (PubMed)

  6. Mouse (Murine) Monoclonal IL1R1 Primary Antibody for FACS - ABIN4896212 : Coffelt, Kersten, Doornebal, Weiden, Vrijland, Hau, Verstegen, Ciampricotti, Hawinkels, Jonkers, de Visser: IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. in Nature 2015 (PubMed)

  7. Mouse (Murine) Monoclonal IL1R1 Primary Antibody for FACS - ABIN4896214 : He, Qian, Li, Fan, Li, Wu, Billiar, Wilson, Shi, Fan: TLR4-Upregulated IL-1β and IL-1RI Promote Alveolar Macrophage Pyroptosis and Lung Inflammation through an Autocrine Mechanism. in Scientific reports 2016 (PubMed)

  8. Cow (Bovine) Polyclonal IL1R1 Primary Antibody for ICC, IF - ABIN442876 : Isa, Srivastava, Tiernan, Owens, Rooney, Dockery, Pandit: Hyaluronic Acid Based Hydrogels Attenuate Inflammatory Receptors and Neurotrophins in Interleukin-1β Induced Inflammation Model of Nucleus Pulposus Cells. in Biomacromolecules 2015 (PubMed)

More Antibodies against IL1R1 Interaction Partners

Human Interleukin 1 Receptor, Type I (IL1R1) interaction partners

  1. ligand-activation of GPER (show GPER Antibodies) generates a feedforward loop coupling IL1beta (show IL1B Antibodies) induction by CAFs (show TBX1 Antibodies) to IL1R1 (show IL1RN Antibodies) expression by cancer cells, promoting the up-regulation of IL1beta (show IL1B Antibodies)/IL1R1 (show IL1RN Antibodies) target genes such as PTGES (show PTGES Antibodies), COX2 (show COX2 Antibodies), RAGE (show AGER Antibodies) and ABCG2 (show ABCG2 Antibodies)

  2. this study shows that IL-1a (show IL1A Antibodies) gene variants are not associated with susceptibility to juvenile idiopathic arthritis in Iranian population

  3. The work identifies a pathogenic role of postnatal IL1b (show IL1B Antibodies)/IL-1R1 pathway and subsequent prolonged prominent increase of endocannabinoid signaling in adult seizure susceptibility following prolonged febrile seizures, and highlights IL-1R1 as a potential therapeutic target for preventing the development of epilepsy after infantile febrile seizures.

  4. The results present identification of critical regions within the TIR domain of IL-1 (show IL1A Antibodies) receptor type in humans and mice.

  5. IL1R1 (show IL1RN Antibodies) SNP rs949963 is associated with the susceptibility to asthma in children from Central China and may increase the serum expression of IL1R1 (show IL1RN Antibodies).

  6. Altered expression of EP2 (show SPAG11B Antibodies) in patients with aspirin-exacerbated respiratory disease contributes to deficient induction of IL-1RI, reducing the capacity of IL-1beta (show IL1B Antibodies) to increase COX-2 (show COX2 Antibodies) and mPGES-1 (show PTGES Antibodies) expression, which results in low PGE2 production

  7. investigated the association between four inflammatory cytokines (CD121a, interleukin [IL]-1beta, IL-8 (show IL8 Antibodies), and IL-11 (show IL11 Antibodies)) and coronary heart disease

  8. This study found that the mRNA expression of IL-1R1, TNFR1 (show TNFRSF1A Antibodies), and TNFR2 (show TNFRSF1B Antibodies) was significantly higher in schizophreina

  9. IL-1R1 expression appears to define a tissue regulatory T cell phenotype together with the expression of CD25 (show IL2RA Antibodies), glucocorticoid-induced tumor necrosis factor (show TNF Antibodies) receptor family-related gene and CTLA-4 (show CTLA4 Antibodies).

  10. TNF-alpha (show TNF Antibodies) (-308) GG, IL-10 (show IL10 Antibodies) (-819) TT, IL-10 (show IL10 Antibodies) (-1082) GG and IL1R (+1970) CC genotypes are found to be predominant (p=0.01, p=0.02, p=0.0001 and p=0.001, respectively) in both tuberculoid as well as lepromatous leprosy patients.

Mouse (Murine) Interleukin 1 Receptor, Type I (IL1R1) interaction partners

  1. The work identifies a pathogenic role of postnatal IL1b (show IL1B Antibodies)/IL-1R1 pathway and subsequent prolonged prominent increase of endocannabinoid signaling in adult seizure susceptibility following prolonged febrile seizures.

  2. SER140 treatment postpones the onset of diabetes in female NOD mice by interfering with IL-1beta (show IL1B Antibodies)/Il1 (show IL1A Antibodies) receptor signaling.

  3. IL-1 (show IL1A Antibodies) receptor (IL-1R1) deficiency or blockade limits blood pressure elevation in this model by mitigating sodium reabsorption via the NKCC2 (show SLC12A1 Antibodies) co-transporter in the nephron.

  4. data identify a previously unappreciated Trim24 (show TRIM24 Antibodies)-dependent requirement for IL-1R expression on TH2 cells and an important nonredundant role for T-cell-intrinsic Trim24 (show TRIM24 Antibodies) in TH2-mediated allergy and antihelminth immunity

  5. The results present identification of critical regions within the TIR domain of IL-1 (show IL1A Antibodies) receptor type in humans and mice.

  6. IL-1R1/MyD88 (show MYD88 Antibodies) signaling negatively regulates bone regeneration via impairment of mesenchymal stem cell proliferation, migration and differentiation by inhibiting the Akt (show AKT1 Antibodies)/GSK-3beta (show GSK3b Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  7. adult mice lacking interleukin-1 receptor 1 (show IL1RL1 Antibodies) (IL-1R1) exhibit increased expression of both the excitatory scaffolding protein postsynaptic density-95 (PSD-95 (show DLGAP2 Antibodies)) and inhibitory scaffolding proteingephyrin, respectively, in the hippocampus.

  8. Study provides evidence that IL-1b (show IL1B Antibodies) is key regulatory factor for the postictal suppression, and its receptor IL-1R1 may be a potential target for adjuvant treatment of postictal problems

  9. these studies demonstrate, through the use of novel transgenic mice, that IL1R1 (show IL1RN Antibodies) on neurons and astrocytes differentially mediates aspects of sleep

  10. Data (including data from studies in knockout mice) suggest that up-regulation of ROS (show ROS1 Antibodies)/Nlrp3 (show NLRP3 Antibodies)/Il1b (show IL1B Antibodies)/Il1r1 (show IL1RN Antibodies) (reactive oxygen species/Nlrp3 (show NLRP3 Antibodies)/interleukin 1beta/Il1 (show IL1A Antibodies) receptor 1) signaling causes severe liver disease during Murine hepatitis virus 3 infection.

IL1R1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Alternative names and synonyms associated with IL1R1

  • interleukin 1 receptor, type I (IL1R1) antibody
  • interleukin 1 receptor, type I (Il1r1) antibody
  • CD121a antibody
  • CD121b antibody
  • D2S1473 antibody
  • IL-1R-alpha antibody
  • IL-iR antibody
  • IL1R antibody
  • Il1r-1 antibody
  • IL1RA antibody
  • P80 antibody

Protein level used designations for IL1R1

CD121 antigen-like family member A , IL-1R-1 , IL-1RT-1 , IL-1RT1 , antigen CD121a , interleukin 1 receptor alpha, type I , interleukin receptor 1 , interleukin-1 receptor alpha , interleukin-1 receptor type 1 , interleukin-1 receptor type I , IL-1 receptor alpha chain , IL-1R-alpha , p80 , interleukin 1 beta receptor type 1 short transmembrane form , interleukin 1 beta receptor type 1 soluble form , interleukin 1 bete receptor type 1 long transmembrane form

3554 Homo sapiens
16177 Mus musculus
25663 Rattus norvegicus
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