anti-Human IL1R1 antibody for Immunoprecipitation

Recommended IL1R1 Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor, Type I (IL1R1) Antibodies
  • CD121A
  • D2S1473
  • IL-1R-alpha
  • IL1R
  • IL1RA
  • P80
  • CD121a
  • CD121b
  • IL-iR
  • Il1r-1
  • interleukin 1 receptor, type I
  • IL1R1
  • Il1r1
Epitope
AA 1-332
30
17
14
9
8
8
7
6
6
6
5
5
5
4
4
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
124
85
28
2
2
2
1
1
1
1
1
1
Host
Rabbit
114
45
29
16
11
1
Clonality
Polyclonal
Conjugate
This IL1R1 antibody is un-conjugated
13
12
11
9
5
5
4
3
2
2
2
1
1
1
1
1
1
Application
ELISA, Immunoprecipitation (IP), Western Blotting (WB)
133
109
59
52
40
15
10
9
7
5
5
5
4
3
2
2
2
2
2
2
1
1
1
1
1
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Catalog No. ABIN1995763
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN116871 EIA IP Rabbit Log in to see Polyclonal 10
1 ABIN1859387 ICC IHC IP WB Rabbit IgG AA 120-208 Log in to see Polyclonal
1 ABIN1172131 ICC IHC IP WB Rabbit IgG AA 21-109 Log in to see Polyclonal
1 ABIN1859389 ICC IHC IP WB Rabbit IgG AA 226-318 Log in to see Polyclonal
1 ABIN470897 IP RIA ELISA Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN799832 IP RIA ELISA Rabbit Extracellular Domain Log in to see Polyclonal
1 ABIN1837948 IP WB Rat IgG1 Log in to see Reg21
1 ABIN1837950 IP WB Rat IgG1 Log in to see D1f3
1 ABIN1837949 IP WB Rat IgG1 Log in to see Reg20

Top referenced anti-IL1R1 antibody for Immunoprecipitation

Similar anti-IL1R1 Antibodies

Application / Reactivity Human
Cell Culture (CC) 1 Antibodies
ELISA 81 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 16 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 5 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunohistochemistry (IHC) 48 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Immunoprecipitation (IP) 10 Antibodies
Neutralization (Neut) 1 Antibodies
Radioimmunoassay (RIA) 15 Antibodies
Western Blotting (WB) 88 Antibodies

General

Antigen Interleukin 1 Receptor, Type I (IL1R1) Antibodies
Epitope AA 1-332
(30), (17), (14), (9), (8), (8), (7), (6), (6), (6), (5), (5), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(124), (85), (28), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(114), (45), (29), (16), (11), (1)
Clonality
Polyclonal
Conjugate This IL1R1 antibody is un-conjugated
(13), (12), (11), (9), (5), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application ELISA, Immunoprecipitation (IP), Western Blotting (WB)
(133), (109), (59), (52), (40), (15), (10), (9), (7), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-IL1R1 Antibody

Target Details IL1R1 Application Details Handling ProductDetails: References for anti-IL1R1 antibody (ABIN1995763) Images
Specificity Human IL1R1 / CD121a
Characteristics Produced in rabbits immunized with purified, recombinant Human IL1R1 (rh IL1R1, ABIN2002132 NP_000868.1, Met 1-Thr 332,. IL1R1 specific IgG was purified by human IL1R1 affinity chromatography.
Purification purified by affinity chromatography
Sterility 0.2 μm filtered
Immunogen Recombinant Human IL1R1 protein (ABIN2002132)
Isotype IgG

Target Details IL1R1

Product Details anti-IL1R1 Antibody Application Details Handling ProductDetails: References for anti-IL1R1 antibody (ABIN1995763) Images back to top
Antigen
Alternative Name IL1R1 (IL1R1 Antibody Abstract)
Background Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA). IL-1R1/CD121a is an important mediator involved in many cytokine induced immune and inflammatory responses. This protein has been characterized by pharmacological and molecular techniques in the mouse brain. The spindle-shaped astrocytes enclose the wound, separating the healthy from damaged neural tissue. The shape change and subsequent repair processes are IL-1β activity-dependent, acting through the IL-1 type 1 receptor (IL-1R1), as co-application of the IL-1type 1 receptor antagonist protein (IL-1ra) blocks IL-1β induced effects. In the spleen, a slight increase in IL-1R AcP and IL-1R1 was observed during the first hours following LPS stimulation. In conclusion, IL-1R AcP mRNA is expressed in the brain and in other tissues where IL-1R1/CD121a transcripts are found. However, the regulation of its expression is distinct from IL-1R1/CD121a. The high level of expression and the lack of regulation of IL-1R AcP transcripts in the brain under inflammatory conditions suggest that the protein might be constitutively expressed in excess.
NCBI Accession NP_000868.1
Research Area Immunology
Pathways NF-kappaB Signaling, Carbohydrate Homeostasis

Application Details

Product Details anti-IL1R1 Antibody Target Details IL1R1 Handling ProductDetails: References for anti-IL1R1 antibody (ABIN1995763) Images back to top
Application Notes WB: 5-10 μg/mL
ELISA: 0.5-1.0 μg/mL
This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human IL1R1. The detection limit for Human IL1R1 is 0.00245 ng/well.
IP: 1-4 μg/mg of lysate
Restrictions For Research Use only

Handling

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details ProductDetails: References for anti-IL1R1 antibody (ABIN1995763) Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months

ProductDetails: References for anti-IL1R1 antibody (ABIN1995763)

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details Handling Images back to top
Background publications

Vigers, Anderson, Caffes, Brandhuber: "Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta." in: Nature, Vol. 386, Issue 6621, pp. 190-4, 1997

Images

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details Handling ProductDetails: References for anti-IL1R1 antibody (ABIN1995763) back to top
Supplier Images
Western Blotting (WB) image for anti-IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 1-332) (ABIN1995763) anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody
Immunoprecipitation (IP) image for anti-IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 1-332) (ABIN1995763) anti-Interleukin 1 Receptor, Type I (IL1R1) (AA 1-332) antibody (Image 2)