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|Antigen||Interleukin 1 Receptor, Type I (IL1R1) Antibodies|
|Epitope||Extracellular Domain Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This IL1R1 antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunoprecipitation (IP)
|1 reference available|
|Supplier||Log in to see|
Product Details anti-IL1R1 AntibodyTarget Details IL1R1 Application Details Handling ProductDetails: References for anti-IL1R1 antibody (ABIN120264) Images
|Purification||Affinity chromatography on Protein G|
|Immunogen||Extracellular domain of murine IL-1R. Spleen cells from immunised Armenian Hamster were fused with cells of the mouse P3X63.Ag 8-653 myeloma cell line.|
Target Details IL1R1Product Details anti-IL1R1 Antibody Application Details Handling ProductDetails: References for anti-IL1R1 antibody (ABIN120264) Images back to top
|Alternative Name||CD121a / IL1R1 (IL1R1 Antibody Abstract)|
|Background||CD121a is weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts. The ligands for CD121a are the interleukin-1 (IL-1) family members, IL-1 alpha, IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a.Synonyms: IL-1R-alpha, IL1R, IL1RA, IL1RT1, Interleukin-1 receptor alpha, Interleukin-1 receptor type 1, Interleukin-1 receptor type I|
|Research Area||CD Antigens, Surface Receptors of Immune Cells|
|Pathways||NF-kappaB Signaling, Carbohydrate Homeostasis|
Application DetailsProduct Details anti-IL1R1 Antibody Target Details IL1R1 Handling ProductDetails: References for anti-IL1R1 antibody (ABIN120264) Images back to top
Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL1R1 Antibody Target Details IL1R1 Application Details ProductDetails: References for anti-IL1R1 antibody (ABIN120264) Images back to top
|Buffer||PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ProductDetails: References for anti-IL1R1 antibody (ABIN120264)Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details Handling Images back to top
Rogers, Sheehan, Brunt, Dower, Unanue, Schreiber: "Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 3, pp. 1011-5, 1992