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anti-Rat (Rattus) IL1R1 antibody for Flow Cytometry

Recommended IL1R1 Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor, Type I (IL1R1) Antibodies
  • CD121A
  • D2S1473
  • IL-1R-alpha
  • IL1R
  • IL1RA
  • P80
  • CD121a
  • CD121b
  • IL-iR
  • Il1r-1
  • interleukin 1 receptor, type I
  • IL1R1
  • Il1r1
Epitope
AA 1-352
29
17
14
9
8
7
7
7
6
6
5
5
5
4
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Rat (Rattus)
123
83
26
2
1
1
1
1
1
1
Host
Rabbit
113
45
28
16
11
1
Clonality
Monoclonal
Conjugate
This IL1R1 antibody is un-conjugated
13
12
11
9
5
5
4
3
2
2
2
1
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS)
132
108
58
50
41
15
10
8
7
6
5
5
4
3
2
2
2
2
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN2001599
$ 273.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2692422 FACS FITC Rabbit IgG AA 1-352 Log in to see 007
1 ABIN2692424 FACS PE Rabbit IgG AA 1-352 Log in to see 007

Similar anti-IL1R1 Antibodies

Application / Reactivity Rat (Rattus)
Cell Culture (CC) 1 Antibodies
ELISA 20 Antibodies
ELISA (Detection) 1 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunohistochemistry (IHC) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 17 Antibodies

General

Antigen Interleukin 1 Receptor, Type I (IL1R1) Antibodies
Epitope AA 1-352
(29), (17), (14), (9), (8), (7), (7), (7), (6), (6), (5), (5), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Rat (Rattus)
(123), (83), (26), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(113), (45), (28), (16), (11), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL1R1 antibody is un-conjugated
(13), (12), (11), (9), (5), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application ELISA, Flow Cytometry (FACS)
(132), (108), (58), (50), (41), (15), (10), (8), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-IL1R1 Antibody

Target Details IL1R1 Application Details Handling Images
Specificity Rat IL-1R1 / CD121a
Has cross-reactivity in ELISA with
Mouse IL1R1
No cross-reactivity in ELISA with
Human IL1R1
Human IL1R3
Human IL1R8
Human IL1R2
Human IL18R1
Cross-Reactivity Mouse (Murine)
No Cross-Reactivity Human
Characteristics This antibody was obtained from a rabbit immunized with purified, recombinant Rat IL-1R1 / CD121a (rR IL-1R1 / CD121a, ABIN2009064 NP_037255.3, Met1-Lys352,.
Sterility 0.2 μm filtered
Immunogen Recombinant Rat IL-1R1 / CD121a protein (ABIN2009064)
Clone 007
Isotype IgG

Target Details IL1R1

Product Details anti-IL1R1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL1R1 (IL1R1 Antibody Abstract)
Background Interleukin 1 receptor, type I (IL1R1), also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor that belongs to the IL-1 receptor family. IL1R1 is a receptor for both interleukin alpha (IL1A) and interleukin beta (IL1B), and also associates with interleukin-1 receptor antagonist protein (IL-1RA). There are two distinct types of receptors that bind the pleiotropic cytokines IL1A and IL1B: the type I is an 80 kDa transmembrane protein expressed predominantly by T cells, fibroblasts, and endothelial cells and appears to mediate all the known IL-1 biological functions. However, the type II receptor is a 68 kDa transmembrane protein with a short cytoplamic domain and serves as a decoy for IL-1. IL1R1 structurally consists of three C2-type Ig-like domains and one TIR domain. As important mediators involved in many immune and inflammatory responses, the agonists IL1A and IL1B bind to IL1R1, leading to the signal transduction and activation of NF-kappa- B. Formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2 is indepensible for the signaling processes. Recombinant soluble form of IL1R1 is thus a potent antagonist of IL-1 function.
NCBI Accession NP_037255.3
Research Area Immunology
Pathways NF-kappaB Signaling, Carbohydrate Homeostasis

Application Details

Product Details anti-IL1R1 Antibody Target Details IL1R1 Handling Images back to top
Application Notes ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat IL1R1. The detection limit for Rat IL1R1 is approximately 0.00245 ng/well.
FCM: 0.5-2 μg/Test
Restrictions For Research Use only

Handling

Product Details anti-IL1R1 Antibody Target Details IL1R1 Application Details Images back to top
Format Liquid
Buffer 0.2 μm filtered solution in PBS with 5 % trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C,-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Expiry Date 12 months