|Antigen||Interleukin 1 Receptor Antagonist (IL1RN) Antibodies|
|Conjugate||This IL1RN antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
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Product Details anti-IL1RN AntibodyTarget Details IL1RN Application Details Handling Images
|Immunogen||IL1 RA antibody was raised in rabbit using highly pure recombinant human IL-1 A as the immunogen.|
Target Details IL1RNProduct Details anti-IL1RN Antibody Application Details Handling Images back to top
|Alternative Name||IL1RA (IL1RN Antibody Abstract)|
|Background||Interleukin-1 receptor antagonist (IL1RA) is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and type II receptors. IL1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease.|
|Molecular Weight||17.2 kDa (predicted detection band MW)|
|Research Area||Proteases, Enzymes, Cytokines, Growth Factors|
|Pathways||NF-kappaB Signaling, Hormone Transport|
Application DetailsProduct Details anti-IL1RN Antibody Target Details IL1RN Handling Images back to top
ELISA: 0.5-2 µg/mL, Inhibition: 2.5-3.7 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL1RN Antibody Target Details IL1RN Application Details Images back to top
|Buffer||Lyophilized from PBS, pH 7.2.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|