anti-Human IL1RN antibody for Neutralization

Recommended IL1RN Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
  • IL1RN
  • DIRA
  • ICIL-1RA
  • IL-1RN
  • IL-1ra
  • IL-1ra3
  • IL1F3
  • IL1RA
  • IRAP
  • MVCD4
  • IRAP1
  • F630041P17Rik
  • icIL-1ra
  • IL-1RA
  • interleukin 1 receptor antagonist
  • interleukin 1 receptor, type I
  • IL1RN
  • Il1rn
  • IL1R1
Reactivity
Human
178
34
30
12
9
9
5
5
4
4
4
1
Host
Rabbit
150
78
6
5
4
2
Clonality
Polyclonal
Conjugate
This IL1RN antibody is un-conjugated
34
24
6
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), ELISA, Western Blotting (WB)
173
118
63
27
22
22
19
14
14
13
12
11
8
4
3
3
2
2
1
Supplier
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Catalog No. ABIN1102536
$ 595.83
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN209329 FACS IHC Neut RIA ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2291241 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2291249 Neut ELISA WB APC Rabbit IgG Log in to see Polyclonal
1 ABIN2291243 Neut ELISA WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN2291245 Neut ELISA WB PE Rabbit IgG Log in to see Polyclonal
1 ABIN2291247 Neut ELISA WB Alkaline Phosphatase (AP) Rabbit IgG Log in to see Polyclonal
1 ABIN2291251 Neut ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN2291253 Neut ELISA WB FITC Rabbit IgG Log in to see Polyclonal

General

Antigen Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
Reactivity Human
(178), (34), (30), (12), (9), (9), (5), (5), (4), (4), (4), (1)
Host Rabbit
(150), (78), (6), (5), (4), (2)
Clonality
Polyclonal
Conjugate This IL1RN antibody is un-conjugated
(34), (24), (6), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut), ELISA, Western Blotting (WB)
(173), (118), (63), (27), (22), (22), (19), (14), (14), (13), (12), (11), (8), (4), (3), (3), (2), (2), (1)
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Product Details anti-IL1RN Antibody

Target Details IL1RN Application Details Handling Images
Brand IHC-plus™
Specificity Human IL-1RA
Purification Immunoaffinity purified
Immunogen E.coli derived recombinant Human IL-1RA.

Type of Immunogen: Cell extract
Isotype IgG

Target Details IL1RN

Product Details anti-IL1RN Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL1RN (IL1RN Antibody Abstract)
Background Name/Gene ID: IL1RN
Family: IL-1

Synonyms: IL1RN, Anakinra, DIRA, IL-1ra, IL-1RN, IL1F3, IL1RA, MVCD4, IL1 inhibitor, IL1RN (IL1F3), IRAP, ICIL-1RA, IL-1ra3
Gene ID 3557
UniProt P18510
Pathways NF-kappaB Signaling, Hormone Transport

Application Details

Product Details anti-IL1RN Antibody Target Details IL1RN Handling Images back to top
Application Notes Approved: ELISA (0.5 - 2 μg/mL), IHC-P (5 μg/mL), Neut (2.5 - 3.7 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: Immunohistochemistry: LS-B7435 in an IHC-plus antibody, validated by our pathologists for use in IHC against formalin-fixed, paraffin-embedded human tissues (IHC validation procedure). A concentration of 5 μg/mL is recommended. Neutralization: To yield one-half maximal inhibition [ND] of the biological activity of Human IL-1RA (50 ng/mL) and Human IL-1alpha (50 pg/mL), a concentration of 2.5-3.7 μg/mL of this antibody is required. ELISA: To detect Human IL-1RA by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human IL-1RA (LS-C104474) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human IL-1RA. Western Blot: To detect Human IL-1RA by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant Human IL-1RA is 1.5-3 ng/lane, under either reducing or non-reducing conditions.
Restrictions For Research Use only

Handling

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Images back to top
Format Lyophilized
Reconstitution Sterile water
Concentration Lot specific
Buffer Lyophilized from PBS, pH 7.2
Handling Advice Avoid freeze/thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store Lyophilized at room temperature up to 1 month
Reconstituted for up to two weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.

Images

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN1102536) Anti-IL1RN / IL-1RA antibody IHC staining of human skin, epidermis. Immunohistochemis...