anti-Rat (Rattus) IL1RN antibody for Immunohistochemistry

Recommended IL1RN Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
  • IL1RN
  • DIRA
  • ICIL-1RA
  • IL-1RN
  • IL-1ra
  • IL-1ra3
  • IL1F3
  • IL1RA
  • IRAP
  • MVCD4
  • IRAP1
  • F630041P17Rik
  • icIL-1ra
  • IL-1RA
  • interleukin 1 receptor antagonist
  • interleukin 1 receptor, type I
  • IL1RN
  • Il1rn
  • IL1R1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
178
33
29
12
9
9
5
5
4
4
4
1
Host
Rabbit
150
78
6
5
4
2
Clonality
Polyclonal
Conjugate
This IL1RN antibody is un-conjugated
34
24
6
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
173
119
62
27
22
21
20
14
14
13
12
11
9
4
3
3
2
2
1
Supplier
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Available images

Catalog No. ABIN2405050
$ 588.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.870993 ABIN2423651 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN442533 ICC IF IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal 1
1 ABIN3022879 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2894438 IHC WB Rabbit Log in to see Polyclonal
1 ABIN5565653 FACS ICC IF IHC PE Rabbit AA 27-178 Log in to see Polyclonal
1 ABIN5565649 FACS ICC IF IHC APC Rabbit AA 27-178 Log in to see Polyclonal
1 ABIN5565651 FACS ICC IF IHC FITC Rabbit AA 27-178 Log in to see Polyclonal
1 ABIN2973392 IF/ICC IHC WB Rabbit IgG Log in to see Polyclonal

General

Antigen Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(178), (33), (29), (12), (9), (9), (5), (5), (4), (4), (4), (1)
Host Rabbit
(150), (78), (6), (5), (4), (2)
Clonality
Polyclonal
Conjugate This IL1RN antibody is un-conjugated
(34), (24), (6), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(173), (119), (62), (27), (22), (21), (20), (14), (14), (13), (12), (11), (9), (4), (3), (3), (2), (2), (1)
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Product Details anti-IL1RN Antibody

Target Details IL1RN Application Details Handling Images
Purification Antigen affinity purification
Immunogen Recombinant protein of human IL1RN
Isotype IgG

Target Details IL1RN

Product Details anti-IL1RN Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL1RN (IL1RN Antibody Abstract)
Background The founding members of the interleukin-1 (IL-1) superfamily include pro-inflammatory cytokines IL-1α and IL-1β, and a third protein that acts as an IL-1 receptor antagonist (IL-1RA). At least six similar proteins have been recently identified, including a homolog of IL-1RA (IL1F5). The three better-characterized proteins (IL-1a, IL-1b and IL-1RA) are mainly expressed in macrophages, monocytes, and dendritic cells. IL-1a and IL-1b act as potent inflammatory cytokines that help regulate host defense and immune responses (1). Binding of these pro-inflammatory cytokines to an IL-1 receptor recruits adapter proteins (such as IRAK) to the receptor. Phosphorylation of these adaptor proteins promotes downstream signaling cascades associated with the immune response (2). Altered expression of both IL-1a and IL-1b is associated with an extensive list of human disorders, including Alzheimer's disease, rheumatoid arthritis, psoriasis and various forms of cancer (3,4). IL-1RA acts as an anti-inflammatory cytokine, binding the IL-1 receptor to limit the response to inflammation (5). Because it plays a key role in regulating the inflammatory response, recombinant IL-1RA is a therapeutic agent used in the treatment of diseases such as rheumatoid arthritis. Alternatively, mutation of the corresponding IL-1RA gene may be associated with susceptibility to the development of specific cancers (6).
Synonyms: ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430,
Molecular Weight Observed MW: 20kDa
Pathways NF-kappaB Signaling, Hormone Transport

Application Details

Product Details anti-IL1RN Antibody Target Details IL1RN Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Images back to top
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).

Images

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Handling back to top
Supplier Images
Immunofluorescence (IF) image for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN2405050) Immunofluorescence analysis analysis of MCF7 cell using IL1RN antibody. Blue: DAPI fo...
Immunohistochemistry (IHC) image for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN2405050) Immunohistochemistry of paraffin-embedded human epididymis using IL1RN antibody at di...
Immunohistochemistry (IHC) image for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN2405050) Immunohistochemistry of paraffin-embedded mouse lung using IL1RN antibody at dilution...
Western Blotting (WB) image for anti-Interleukin 1 Receptor Antagonist (IL1RN) antibody (ABIN2405050) Western blot analysis of extracts of various cell lines, using IL1RN antibody.