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anti-Rat (Rattus) IL1RN antibody for Western Blotting

Recommended IL1RN Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
  • DIRA
  • F630041P17Rik
  • ICIL-1RA
  • icIL-1ra
  • IL-1RA
  • IL-1ra
  • IL-1ra3
  • IL-1RN
  • IL1F3
  • IL1RA
  • IL1RN
  • IRAP
  • IRAP1
  • MVCD4
Reactivity
Mouse (Murine), Rat (Rattus), Human
174
28
18
12
9
7
5
5
4
4
2
Host
Rabbit
138
74
7
3
2
2
1
Clonality
Polyclonal
Conjugate
This IL1RN antibody is un-conjugated
33
25
7
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
133
115
40
23
20
18
18
18
11
10
9
8
3
3
3
2
2
1
1
Supplier
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Catalog No. ABIN3022879
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.13398378 ABIN2489457 IHC (fp) IF WB Rabbit IgG Log in to see Polyclonal
0.13398378 ABIN2405050 IF IHC WB Rabbit IgG Log in to see Polyclonal
0.0011731827 ABIN678743 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0011731827 ABIN678745 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0011731827 ABIN678752 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.0011731827 ABIN3198157 IC IF WB Rabbit Log in to see Polyclonal
0.0011731827 ABIN442533 ICC IF IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.0011731827 ABIN2973392 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal

Similar anti-IL1RN Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 109 Antibodies 14 Antibodies 9 Antibodies
Radioimmunoassay (RIA) 2 Antibodies
Neutralization (Neut) 9 Antibodies
Immunoprecipitation (IP) 7 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies 5 Antibodies 4 Antibodies
Immunohistochemistry (IHC) 32 Antibodies 7 Antibodies 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 8 Antibodies 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies 1 Antibodies

General

Antigen Interleukin 1 Receptor Antagonist (IL1RN) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(174), (28), (18), (12), (9), (7), (5), (5), (4), (4), (2)
Host Rabbit
(138), (74), (7), (3), (2), (2), (1)
Clonality
Polyclonal
Conjugate This IL1RN antibody is un-conjugated
(33), (25), (7), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(133), (115), (40), (23), (20), (18), (18), (18), (11), (10), (9), (8), (3), (3), (3), (2), (2), (1), (1)
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Product Details anti-IL1RN Antibody

Target Details IL1RN Application Details Handling Images
Purification Affinity purification
Immunogen Recombinant protein of human IL1RN
Isotype IgG

Target Details IL1RN

Product Details anti-IL1RN Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL1RN (IL1RN Antibody Abstract)
Background The founding members of the interleukin-1 (IL-1) superfamily include pro-inflammatory cytokines IL-1alpha and IL-1beta, and a third protein that acts as an IL-1 receptor antagonist (IL-1RA). At least six similar proteins have been recently identified, including a homolog of IL-1RA (IL1F5). The three better-characterized proteins (IL-1a, IL-1b and IL-1RA) are mainly expressed in macrophages, monocytes, and dendritic cells. IL-1a and IL-1b act as potent inflammatory cytokines that help regulate host defense and immune responses. Binding of these pro-inflammatory cytokines to an IL-1 receptor recruits adapter proteins (such as IRAK) to the receptor. Phosphorylation of these adaptor proteins promotes downstream signaling cascades associated with the immune response. Altered expression of both IL-1a and IL-1b is associated with an extensive list of human disorders, including Alzheimers disease, rheumatoid arthritis, psoriasis and various forms of cancer. IL-1RA acts as an anti-inflammatory cytokine, binding the IL-1 receptor to limit the response to inflammation. Because it plays a key role in regulating the inflammatory response, recombinant IL-1RA is a therapeutic agent used in the treatment of diseases such as rheumatoid arthritis. Alternatively, mutation of the corresponding IL-1RA gene may be associated with susceptibility to the development of specific cancers.
Synonyms: ICIL-1RA, IL-1ra3, IL1F3, IL1RA, IRAP, MGC10430
Gene ID 3557
UniProt P18510
Pathways NF-kappaB Signaling

Application Details

Product Details anti-IL1RN Antibody Target Details IL1RN Handling Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

Images

Product Details anti-IL1RN Antibody Target Details IL1RN Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-IL1RN antibody (Interleukin 1 Receptor Antagonist) (ABIN3022879) Western blot analysis of extracts of various cell lines, using IL1RN antibody.
Immunofluorescence (IF) image for anti-IL1RN antibody (Interleukin 1 Receptor Antagonist) (ABIN3022879) Immunofluorescence analysis of MCF7 cell using IL1RN antibody. Blue: DAPI for nuclear...