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anti-Horse (Equine) Insulin antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • AA986540
  • IDDM2
  • ILPR
  • Ins-2
  • ins1
  • ins1-a
  • InsII
  • Insulin
  • IRDN
  • Mody
  • Mody4
  • MODY10
  • proinsulin
  • xins
  • zgc:109842
Reactivity
Cat (Feline), Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
886
368
249
237
234
117
48
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Host
Mouse
796
180
57
7
2
2
Clonality
Monoclonal
Conjugate
This Insulin antibody is un-conjugated
55
41
40
27
25
24
19
19
17
17
17
17
17
17
17
17
16
16
12
10
7
7
5
5
5
5
5
2
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
570
340
234
196
182
180
150
127
85
56
52
27
13
12
9
8
7
6
5
5
4
3
1
1
1
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Catalog No. ABIN114751
$ 286.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089690165 ABIN114750 IHC (fro) IHC (p) Mouse IgG1 Log in to see K36aC10
0.00089690165 ABIN269653 DB ICC IF IHC (p) IHC RIA Mouse IgG1 Log in to see K36aC10

Top referenced anti-Insulin antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Insulin Antibodies

Application / Reactivity Human Pig (Porcine) Cow (Bovine) Rat (Rattus) Horse (Equine) Rabbit Dog (Canine) Cat (Feline) Guinea Pig Sheep (Ovine)
Western Blotting (WB) 212 Antibodies 108 Antibodies 99 Antibodies 44 Antibodies 1 Antibodies 68 Antibodies
Radioimmunoassay (RIA) 46 Antibodies 14 Antibodies 17 Antibodies 4 Antibodies 2 Antibodies 1 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies
Protein Assay (PrA) 6 Antibodies

General

Antigen Insulin (INS) Antibodies
Reactivity Cat (Feline), Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Pig (Porcine), Rabbit, Rat (Rattus), Sheep (Ovine)
(886), (368), (249), (237), (234), (117), (48), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(796), (180), (57), (7), (2), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Insulin antibody is un-conjugated
(55), (41), (40), (27), (25), (24), (19), (19), (17), (17), (17), (17), (17), (17), (17), (17), (16), (16), (12), (10), (7), (7), (5), (5), (5), (5), (5), (2), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(570), (340), (234), (196), (182), (180), (150), (127), (85), (56), (52), (27), (13), (12), (9), (8), (7), (6), (5), (5), (4), (3), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin Antibody (ABIN114751) Images
Specificity This antibody recognizes purified Insulin from the pancreas of Human, Bovine, Horse, Sheep as well as Proinsulin from Human. Cross reaction has been observed with insulin containing cells in fixed sections of pancreas from Human, Porcine, Dog, Rabbit, Bovine, Sheep, Rat, Guinea Pig and Cat.
Cellular Localization: Cytoplasmic.Cellular Localization
Purification Supernatant
Immunogen Human insulin.
Clone K36aC10
Isotype IgG1

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin Antibody (ABIN114751) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Research Area Neurology, Diabetes, Hormones
Pathways NF-kappaB Signaling, RTK Signaling

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin Antibody (ABIN114751) Images back to top
Application Notes Immunohistochemistry on Formalin/Paraffin Sections: Use a dilution of 1/25-1/50 in anABC method (30 minutes at room temperature). Recommended Positive Control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin Antibody (ABIN114751) Images back to top
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin Antibody (ABIN114751)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Madsen: "Proinsulin-specific monoclonal antibodies. Immunocytochemical application as beta-cell markers and as probes for conversion." in: Diabetes, Vol. 36, Issue 10, pp. 1203-11, 1987

Keilacker, Dietz, Witt, Woltanski, Berling, Ziegler: "Kinetic properties of monoclonal insulin antibodies." in: Biomedica biochimica acta, Vol. 45, Issue 8, pp. 1093-102, 1986