anti-Mouse (Murine) Insulin antibody for Immunohistochemistry (Frozen Sections)

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • insulin-like
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • Ins2
  • LOC100060077
Reactivity
Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
965
396
301
282
261
121
49
6
6
6
5
5
4
2
2
1
1
1
1
1
1
1
Host
Mouse
842
183
54
25
3
1
Clonality
Monoclonal
Conjugate
This Insulin antibody is un-conjugated
57
42
41
28
28
27
23
23
18
17
17
17
17
17
17
16
16
12
11
11
11
11
11
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
622
371
248
234
208
204
161
142
71
66
40
27
18
11
9
8
8
7
5
4
3
3
3
2
2
2
1
1
1
Supplier
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Catalog No. ABIN112214
$ 423.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN255726 IHC (fro) IHC (p) IHC ELISA Mouse IgG1 Log in to see D3E7 (5B6-6)
1 ABIN261236 ELISA IHC (fro) Mouse IgG1 kappa Log in to see 3A6 1
1 ABIN2475108 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7 (5B6-6) 1
1 ABIN1804388 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7 (5B6-6)
1 ABIN768892 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7
1 ABIN1723784 IHC (fro) IHC (p) ELISA Mouse IgG1 Log in to see D3E7
1 ABIN2475107 IHC (fro) ELISA Mouse IgG1 Log in to see D6C4 (5E4-3) 2
1 ABIN112204 EIA IHC (fro) Mouse IgG1 Log in to see 5E4-3
1 ABIN4326055 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326056 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG Log in to see E2-E3-2D11-H5 (same as INS04-INS05)
1 ABIN4326054 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326053 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326057 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG Log in to see E2-E3-2D11-H5 (same as INS04-INS05)
1 ABIN4326058 FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG Log in to see E2-E3-2D11-H5 (same as INS04-INS05)
1 ABIN1819261 IHC (fro) ELISA Guinea Pig IgG Log in to see Polyclonal
1 ABIN4326069 ELISA FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 647 Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326072 ELISA ICC IF IHC (fro) IHC (p) WB Biotin Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326073 ELISA FACS ICC IF IHC (fro) IHC (p) WB DyLight 650 Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326074 ELISA FACS ICC IF IHC (fro) IHC (p) WB DyLight 680 Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)
1 ABIN4326080 ELISA FACS ICC IF IHC (fro) IHC (p) WB DyLight 550 Mouse IgG1 kappa Log in to see E2-E3 (same as INS04)

General

Antigen Insulin (INS) Antibodies
Reactivity Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(965), (396), (301), (282), (261), (121), (49), (6), (6), (6), (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(842), (183), (54), (25), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Insulin antibody is un-conjugated
(57), (42), (41), (28), (28), (27), (23), (23), (18), (17), (17), (17), (17), (17), (17), (16), (16), (12), (11), (11), (11), (11), (11), (5), (5), (5), (5), (5), (5), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(622), (371), (248), (234), (208), (204), (161), (142), (71), (66), (40), (27), (18), (11), (9), (8), (8), (7), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN112214) Images
Specificity This antibody recognizes both Insulin and Proinsulin, but does not react with free C-Peptide.Aff. Const.:6.3 x 108 M-1
Cross-Reactivity (Details) Also reacts to: Proinsulin
Purification Affinity Chromatography on Protein A
Immunogen Recombinant Human Insulin.
Clone D3E7 (5B6-6)
Isotype IgG1

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN112214) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Research Area Neurology, Diabetes, Hormones
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN112214) Images back to top
Application Notes Immunohistochemistry on Frozen Sections. ELISA: This antibody is suitable for use as a Detection antibody with BM507 as the Captureantibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN112214) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN112214)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Qin, Jiao, Chen, Zhou, Liang, Zhong: "Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival." in: Life sciences, Vol. 84, Issue 23-24, pp. 810-6, 2009

Images

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN112214) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Insulin (INS) antibody (ABIN112214) Staining of paraffin embedded human pancreas with mouse anti rat Insulin.