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anti-Rat (Rattus) Insulin antibody for Enzyme Immunoassay

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • insulin-like
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • Ins2
  • LOC100060077
Reactivity
Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
919
393
268
263
262
121
49
6
6
5
5
5
4
3
2
1
1
1
1
1
1
1
Host
Mouse
808
182
54
9
2
1
Clonality
Monoclonal
Conjugate
This Insulin antibody is un-conjugated
56
43
42
28
24
24
19
19
18
17
17
17
17
17
17
16
16
13
11
11
7
7
7
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
617
359
250
226
204
193
164
142
69
66
38
27
14
11
9
9
8
7
5
4
3
2
2
2
2
1
1
Supplier
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Catalog No. ABIN112214
$ 423.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN372838 EIA FACS IF IHC (p) Rabbit IgG Log in to see Polyclonal 2
1 ABIN113504 EIA IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 1
1 ABIN112204 EIA IHC (fro) Mouse IgG1 Log in to see 5E4-3
1 ABIN268266 EIA Mouse IgG1 kappa Log in to see D3E7
1 ABIN4226916 EIA Mouse IgG1 kappa Log in to see D3E7

Top referenced anti-Insulin antibody for Enzyme Immunoassay

Similar anti-Insulin Antibodies

Application / Reactivity Mouse (Murine) Human Cow (Bovine) Pig (Porcine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 5 Antibodies 4 Antibodies 5 Antibodies 1 Antibodies
Cytometry by Time of Flight (CyTOF) 14 Antibodies 10 Antibodies 8 Antibodies 12 Antibodies 4 Antibodies
Western Blotting (WB) 193 Antibodies 106 Antibodies 86 Antibodies 95 Antibodies 51 Antibodies
Radioimmunoassay (RIA) 32 Antibodies 13 Antibodies 18 Antibodies 3 Antibodies 4 Antibodies

General

Antigen Insulin (INS) Antibodies
Reactivity Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(919), (393), (268), (263), (262), (121), (49), (6), (6), (5), (5), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(808), (182), (54), (9), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Insulin antibody is un-conjugated
(56), (43), (42), (28), (24), (24), (19), (19), (18), (17), (17), (17), (17), (17), (17), (16), (16), (13), (11), (11), (7), (7), (7), (5), (5), (5), (5), (5), (5), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(617), (359), (250), (226), (204), (193), (164), (142), (69), (66), (38), (27), (14), (11), (9), (9), (8), (7), (5), (4), (3), (2), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin Antibody (ABIN112214) Images
Specificity This antibody recognizes both Insulin and Proinsulin, but does not react with free C-Peptide.Aff. Const.:6.3 x 108 M-1
Cross-Reactivity (Details) Also reacts to: Proinsulin
Purification Affinity Chromatography on Protein A
Immunogen Recombinant Human Insulin.
Clone D3E7 (5B6-6)
Isotype IgG1

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin Antibody (ABIN112214) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Research Area Neurology, Diabetes, Hormones
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin Antibody (ABIN112214) Images back to top
Application Notes Immunohistochemistry on Frozen Sections. ELISA: This antibody is suitable for use as a Detection antibody with BM507 as the Captureantibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin Antibody (ABIN112214) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin Antibody (ABIN112214)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Qin, Jiao, Chen, Zhou, Liang, Zhong: "Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival." in: Life sciences, Vol. 84, Issue 23-24, pp. 810-6, 2009

Images

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling References for anti-Insulin Antibody (ABIN112214) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Insulin antibody (INS) (ABIN112214) Staining of paraffin embedded human pancreas with mouse anti rat Insulin.