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anti-Human Insulin Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Insulin Receptor Antibody (supplied by: Log in to see )

Antigen
Insulin Receptor (INSR) Antibodies
  • 18402
  • CG18402
  • DIHR
  • DILR
  • DIR
  • DIRH
  • DIRbeta
  • DInR
  • DInr
  • Dir-a
  • Dir-b
  • Dmel\\CG18402
  • INR
  • INS
  • IR
  • Inr
  • Inr-alpha
  • Inr-beta
  • InsR
  • dINR
  • dIR
  • dIRH
  • dInR
  • dInr
  • dInsR
  • dinr
  • dir
  • er10
  • inr
  • insulin/insulin-like growth factor receptor
  • l(3)05545
  • l(3)93Dj
  • l(3)er10
  • lnR
  • INSR
  • NV14476
  • CD220
  • HHF5
  • 4932439J01Rik
  • D630014A15Rik
  • IR-A
  • IR-B
  • ir-A
  • ir
  • cd220
  • hhf5
  • CTK-1
  • Insulin-like receptor
  • insulin receptor
  • insulin receptor precursor
  • InR
  • INSR
  • Insr
  • insr
  • DAF-2
Epitope
AA 59-75, N-Term
36
31
21
17
17
14
12
9
8
7
7
6
5
5
5
5
5
4
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
307
124
92
22
22
21
20
17
17
9
5
5
3
1
1
1
1
1
Host
Rabbit
243
88
8
1
1
Clonality
Polyclonal
Conjugate
This Insulin Receptor antibody is un-conjugated
24
18
12
11
9
9
4
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
205
142
70
55
43
32
17
16
13
12
9
8
7
7
3
2
2
2
Supplier
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Catalog No. ABIN1106088
$ 313.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.155347 ABIN213622 IHC (p) Rabbit Internal Region Log in to see Polyclonal
12.155347 ABIN4326211 IHC IHC (p) Rabbit IgG Center Log in to see Polyclonal
12.155347 ABIN213623 IHC (p) Rabbit Internal Region Log in to see Polyclonal
12.155347 ABIN4326208 IHC (p) Rabbit Log in to see Polyclonal
1 ABIN359886 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
1 ABIN671841 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal 2
1 ABIN392002 IHC (p) WB Rabbit Ig AA 21-52, N-Term Log in to see Polyclonal
1 ABIN302612 IHC (p) Rabbit Chain beta, Internal Region Log in to see Polyclonal
1 ABIN1498892 IHC (p) WB Rabbit IgG AA 816-988 Log in to see Polyclonal
1 ABIN2854945 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN604778 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1102575 FACS IHC (p) Mouse IgG1, kappa Exon 3 Log in to see 83-7
1 ABIN386229 IHC (p) IP ELISA WB Mouse IgG1 Log in to see CT-3
1 ABIN1735947 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1735948 IHC (p) Rabbit IgG Internal Region Log in to see Polyclonal
1 ABIN1998203 IHC (p) ELISA Rabbit IgG AA 1-956 Log in to see Polyclonal
1 ABIN3201536 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 1024-1298 Log in to see
1 ABIN2479300 IHC (p) Rabbit IgG Log in to see Polyclonal 4
1 ABIN381200 IHC (p) WB Rabbit Tyr1185 Log in to see Polyclonal
1 ABIN599777 IHC (p) WB Rabbit AA 59-75 Log in to see Polyclonal

Top referenced anti-Insulin Receptor antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Insulin Receptor Antibodies

Application / Reactivity Dog (Canine) Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 6 Antibodies 3 Antibodies 1 Antibodies
Western Blotting (WB) 19 Antibodies 173 Antibodies 103 Antibodies 77 Antibodies
Neutralization (Neut) 7 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Immunoprecipitation (IP) 51 Antibodies 15 Antibodies 16 Antibodies 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 44 Antibodies 13 Antibodies 11 Antibodies

General

Antigen Insulin Receptor (INSR) Antibodies
Epitope AA 59-75, N-Term
(36), (31), (21), (17), (17), (14), (12), (9), (8), (7), (7), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(307), (124), (92), (22), (22), (21), (20), (17), (17), (9), (5), (5), (3), (1), (1), (1), (1), (1)
Host Rabbit
(243), (88), (8), (1), (1)
Clonality
Polyclonal
Conjugate This Insulin Receptor antibody is un-conjugated
(24), (18), (12), (11), (9), (9), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(205), (142), (70), (55), (43), (32), (17), (16), (13), (12), (9), (8), (7), (7), (3), (2), (2), (2)
Pubmed 1 reference available
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Product Details anti-Insulin Receptor Antibody

Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor Antibody (ABIN1106088) Images
Sequence Sequence is identical to the related Rat and Mouse sequence.
Specificity Recognizes Anti-Insulin Receptor alpha. No cross reactivity with other proteins.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat and Canine (Dog).
Purification Immunoaffinity Chromatography
Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of Human Insulin R alpha (59-75 aa)
Isotype IgG

Target Details Insulin Receptor

Product Details anti-Insulin Receptor Antibody Application Details Handling References for anti-Insulin Receptor Antibody (ABIN1106088) Images back to top
Antigen
Alternative Name CD220 / INSR (INSR Antibody Abstract)
Background Insulin receptor is a tetramer of 2 alpha and 2 beta subunits. The alpha and beta subunits are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. The insulin receptor has an intrinsic tyrosine kinase activity that is essential for signal transduction. A mutant insulin receptor gene lacking almost the entire kinase domain has been identified in an individual with type A insulin resistance and acanthosis nigricans. (1)Synonyms: Insulin Receptor
Gene ID 11255
NCBI Accession NP_000199
UniProt P06213
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity

Application Details

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Handling References for anti-Insulin Receptor Antibody (ABIN1106088) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details References for anti-Insulin Receptor Antibody (ABIN1106088) Images back to top
Reconstitution Restore with 0.2 mL of distilled water to a concentration of 0.5 mg/mL.
Concentration 0.5 mg/mL
Buffer 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide, 5 mg BSA
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin Receptor Antibody (ABIN1106088)

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling Images back to top
Background publications

Taira, Taira, Hashimoto, Shimada, Suzuki, Kanatsuka, Nakamura, Ebina, Tatibana, Makino: "Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor." in: Science (New York, N.Y.), Vol. 245, Issue 4913, pp. 63-6, 1989

Images

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor Antibody (ABIN1106088) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Insulin Receptor antibody (INSR) (AA 59-75) (ABIN1106088) Immunohistochemical staining of Rat Cardiac Muscle.
Western Blotting (WB) image for anti-Insulin Receptor antibody (INSR) (AA 59-75) (ABIN1106088) Lane 1: MCF7 Whole Cell Lysate. Lane 2: HeLa Whole Cell Lysate. Lane 3: Jurkat Whole ...