Insulin Receptor (INSR) Antibodies
This Insulin Receptor antibody is un-conjugated
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BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human).
Insulin Receptor (
INSR Antibody Abstract)
INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).
Cardiovascular, Atherosclerosis, Tyrosine Kinases, Hormones, Diabetes, Receptors
NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
Insulin Receptor antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200 - 1:400.
For Research Use only
PBS, 0.1 % sodium azide.
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
As with all antibodies avoid freeze/thaw cycles.
4 °C/-80 °C
Insulin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
anti-Insulin Receptor (INSR) (Internal Region) antibody