anti-Rabbit Insulin Receptor antibody for Western Blotting

Recommended Insulin Receptor Antibody (supplied by: Log in to see )

Antigen
Insulin Receptor (INSR) Antibodies
  • 18402
  • CG18402
  • DIHR
  • DILR
  • DIR
  • DIRH
  • DIRbeta
  • DInR
  • DInr
  • Dir-a
  • Dir-b
  • Dmel\\CG18402
  • INR
  • INS
  • IR
  • Inr
  • Inr-alpha
  • Inr-beta
  • InsR
  • dINR
  • dIR
  • dIRH
  • dInR
  • dInr
  • dInsR
  • dinr
  • dir
  • er10
  • inr
  • insulin/insulin-like growth factor receptor
  • l(3)05545
  • l(3)93Dj
  • l(3)er10
  • lnR
  • INSR
  • NV14476
  • CD220
  • HHF5
  • 4932439J01Rik
  • D630014A15Rik
  • IR-A
  • IR-B
  • ir-A
  • ir
  • cd220
  • hhf5
  • CTK-1
  • Insulin-like receptor
  • insulin receptor
  • insulin receptor precursor
  • InR
  • INSR
  • Insr
  • insr
  • DAF-2
Epitope
Middle Region
38
34
31
22
17
14
12
10
9
7
7
6
6
6
5
5
5
5
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
329
131
94
23
21
20
19
17
16
8
5
4
3
1
1
1
1
1
Host
Rabbit
253
96
13
1
1
Clonality
Polyclonal
Conjugate
This Insulin Receptor antibody is un-conjugated
27
18
13
11
10
9
6
5
4
4
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
217
143
73
57
47
46
17
13
13
12
11
8
7
7
6
3
2
2
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Catalog No. ABIN2776774
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN2776773 WB Rabbit Middle Region Log in to see Polyclonal
3.2182703 ABIN926933 IHC WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN331470 WB Mouse IgG1 Cytoplasmic Domain Log in to see C18C4
1 ABIN2972579 IF/ICC IHC WB Rabbit C-Term, pTyr1361 Log in to see Polyclonal
1 ABIN2972799 WB Rabbit C-Term, pTyr1355 Log in to see Polyclonal

General

Antigen Insulin Receptor (INSR) Antibodies
Epitope Middle Region
(38), (34), (31), (22), (17), (14), (12), (10), (9), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(329), (131), (94), (23), (21), (20), (19), (17), (16), (8), (5), (4), (3), (1), (1), (1), (1), (1)
Host Rabbit
(253), (96), (13), (1), (1)
Clonality
Polyclonal
Conjugate This Insulin Receptor antibody is un-conjugated
(27), (18), (13), (11), (10), (9), (6), (5), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(217), (143), (73), (57), (47), (46), (17), (13), (13), (12), (11), (8), (7), (7), (6), (3), (2), (2)
Pubmed 1 reference available
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Product Details anti-Insulin Receptor Antibody

Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor antibody (ABIN2776774) Images
Blocking Peptide Blocking peptide for this product available: ABIN978574
Sequence ENNVVHLMWQ EPKEPNGLIV LYEVSYRRYG DEELHLCVSR KHFALERGCR
Predicted Reactivity Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against INSR. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human INSR

Target Details Insulin Receptor

Product Details anti-Insulin Receptor Antibody Application Details Handling References for anti-Insulin Receptor antibody (ABIN2776774) Images back to top
Antigen
Alternative Name INSR (INSR Antibody Abstract)
Background This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream media
Alias Symbols: CD220, HHF5
Protein Interaction Partner: KRT31, UBC, ARRB2, MOK, Grb2, Hgf, DOK1, SH2B1, Stat5b, TEAD1, STAT5A, JAK2, JAK1, IRS1, IRF7, PLCG1, GRB10, Socs6, Socs1, SOCS3, SH2B2, HGS, INPPL1, Calmodulin, Mad2l1, KRT27, DOK5, DOK4, SNX6, SNX4, SNX2, ACP1, PTPN2, SYNCRIP, FRS2, PIK3R3, VAV3, ARHGAP
Protein Size: 1382
Molecular Weight 154 kDa
Gene ID 3643
NCBI Accession NM_000208, NP_000199
UniProt P06213
Pathways NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity

Application Details

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Handling References for anti-Insulin Receptor antibody (ABIN2776774) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1382 AA

Restrictions For Research Use only

Handling

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details References for anti-Insulin Receptor antibody (ABIN2776774) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Insulin Receptor antibody (ABIN2776774)

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling Images back to top
Background publications

Netzer, Freudenberg, Heinze, Heinze-Kuhn, Goebel, McCarthy, Roses, Göbel, Todt, Kubisch: "Replication study of the insulin receptor gene in migraine with aura." in: Genomics, Vol. 91, Issue 6, pp. 503-7, 2008

Images

Product Details anti-Insulin Receptor Antibody Target Details Insulin Receptor Application Details Handling References for anti-Insulin Receptor antibody (ABIN2776774) back to top
Supplier Images
Western Blotting (WB) image for anti-Insulin Receptor (INSR) (Middle Region) antibody (ABIN2776774) WB Suggested Anti-INSR Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...