anti-Mouse (Murine) Integrin beta 2 antibody for Immunocytochemistry

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • ITGB2
  • 2E6
  • AI528527
  • Cd18
  • LAD
  • LCAMB
  • Lfa1
  • MF17
  • CD18
  • LFA-1
  • MAC-1
  • MFI7
  • AI256028
  • LTbetaR
  • Ltar
  • TNF-R-III
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNFRrp
  • Tnfbr
  • Tnfrsf3
  • D12S370
  • LT-BETA-R
  • TNFR3
  • TNFRSF3
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  • integrin, beta 2
  • integrin beta 2
  • lymphotoxin B receptor
  • lymphotoxin beta receptor (TNFR superfamily, member 3)
  • ITGB2
  • Itgb2
  • CD18
  • Ltbr
  • LTBR
Reactivity
Human, Mouse (Murine)
490
215
118
44
26
21
21
5
4
3
3
3
3
3
2
1
1
1
Host
Mouse
361
165
162
15
3
1
Clonality
Monoclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
88
74
53
20
15
12
9
8
8
7
7
7
6
6
6
6
5
5
5
5
4
3
3
3
3
3
3
3
3
2
2
2
1
1
Application
Immunocytochemistry (ICC), ELISA
488
291
203
147
95
89
75
68
53
40
27
18
11
9
7
7
6
2
1
1
1
1
1
1
1
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Catalog No. ABIN969014
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2869416 ELISA ICC Mouse IgG2b Log in to see 10E12
1 ABIN439881 ELISA FACS ICC IHC IHC (fro) IHC (p) IP WB Biotin Rat IgG2a kappa Log in to see C71-16
1 ABIN4327007 ELISA ICC IF Mouse IgG2b Log in to see 10E12
1 ABIN439880 FACS ICC IHC IHC (fro) IHC (p) IP WB FITC Rat IgG2a kappa Log in to see C71-16
1 ABIN1859502 ICC IHC IP WB Rabbit IgG AA 431-652 Log in to see Polyclonal

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Reactivity Human, Mouse (Murine)
(490), (215), (118), (44), (26), (21), (21), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1)
Host Mouse
(361), (165), (162), (15), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 2 antibody is un-conjugated
(88), (74), (53), (20), (15), (12), (9), (8), (8), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Application Immunocytochemistry (ICC), ELISA
(488), (291), (203), (147), (95), (89), (75), (68), (53), (40), (27), (18), (11), (9), (7), (7), (6), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN969014) Images
Purification Ascites
Immunogen Purified recombinant fragment of CD18 expressed in E. Coli.
Clone 1-00E-13
Isotype IgG2b

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 antibody (ABIN969014) Images back to top
Antigen
Alternative Name CD18 (ITGB2 Antibody Abstract)
Background CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Molecular Weight 85 kDa
Gene ID 3689
HGNC 3689
Research Area Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 antibody (ABIN969014) Images back to top
Application Notes ELISA: 1:10000, ICC: 1:200 - 1:1000
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 antibody (ABIN969014) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-Integrin beta 2 antibody (ABIN969014)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Product cited in:

Chakrabarti, Patel: "The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils." in: Microcirculation (New York, N.Y. : 1994), Vol. 15, Issue 6, pp. 555-67, 2008

Doisne, Castaigne, Deruyffelaere, Dieu-Nosjean, Chamot, Alcaide-Loridan, Charron, Al-Daccak: "The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes." in: Molecular immunology, Vol. 45, Issue 3, pp. 709-18, 2007

Li, Tang, Puan, Law, Tan: "The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24310-9, 2007

Images

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN969014) back to top
Supplier Images
Immunocytochemistry (ICC) image for anti-Integrin beta 2 (ITGB2) antibody (ABIN969014) Figure 1: Confocal immunofluorescence analysis of HL60 cells using CD18 mouse mAb (gr...
Immunocytochemistry (ICC) image for anti-Integrin beta 2 (ITGB2) antibody (ABIN969014) Figure 2: Confocal immunofluorescence analysis of BCBL-1 cells (left) and L1210 cells...