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anti-Mouse (Murine) Integrin beta 2 antibody for Immunohistochemistry (Frozen Sections)

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • 2E6
  • AI256028
  • AI528527
  • CD18
  • Cd18
  • D12S370
  • ITGB2
  • LAD
  • LCAMB
  • LFA-1
  • Lfa1
  • LT-BETA-R
  • Ltar
  • LTbetaR
  • MAC-1
  • MF17
  • MFI7
  • TNF-R-III
  • Tnfbr
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNFR3
  • TNFRrp
  • TNFRSF3
  • Tnfrsf3
Reactivity
Mouse (Murine)
467
208
111
39
39
21
20
14
3
3
2
2
2
2
2
2
2
1
1
Host
Rat
363
186
155
5
3
1
Clonality
Monoclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
92
77
53
19
14
11
9
8
7
7
7
6
6
6
6
6
6
6
5
4
3
3
3
3
3
3
3
2
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
497
275
273
158
105
104
84
61
44
34
20
9
7
6
5
3
2
1
1
1
1
1
Supplier
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Catalog No. ABIN118151
$ 819.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000883884 ABIN319556 FACS IHC (fro) IP Rat IgG2a Log in to see YTS213-1 1
0.000883884 ABIN457404 Func FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see M18-2 10
0.000883884 ABIN118149 FACS IHC (fro) IP Rat IgG2a Log in to see YTS 213-1 1
0.000883884 ABIN457430 Func FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see M18-2 8
0.000883884 ABIN1176955 BR IHC (fro) FACS IP Rat IgG1, kappa Log in to see GAME-46 3
0.000883884 ABIN1176975 BR Func IHC (f) IHC (fro) FACS Rat IgG2a, kappa Log in to see M18-2 6
0.000883884 ABIN439882 FACS IHC (fro) IHC (p) IP IHC WB PE Rat IgG2a kappa Log in to see C71-16
0.000883884 ABIN439881 ELISA FACS ICC IHC IHC (fro) IHC (p) IP WB Biotin Rat IgG2a kappa Log in to see C71-16
0.000883884 ABIN262325 FACS IHC (fro) IHC (p) IP IHC WB Rat IgG2a kappa Log in to see M18-2
0.000883884 ABIN439880 FACS ICC IHC IHC (fro) IHC (p) IP WB FITC Rat IgG2a kappa Log in to see C71-16
0.000883884 ABIN2689032 BR IHC (fro) FACS IP Rat IgG1, kappa Log in to see GAME 3
0.000883884 ABIN2689033 BR IHC (f) IHC (fro) FACS IP WB Rat IgG2a, kappa Log in to see M18-2 7
0.000883884 ABIN490166 Func FACS IHC (fro) IP WB Rat IgG2a Log in to see M18-2
0.000883884 ABIN226345 FACS IHC (fro) IHC (p) IP WB Biotin Rat IgG2a, kappa Log in to see
0.000883884 ABIN1859502 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 431-652 Log in to see Polyclonal
0.000883884 ABIN490178 Func FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see M18-2
0.000883884 ABIN212948 FACS IHC (fro) IP Rat IgG2a Log in to see
0.000883884 ABIN2478881 IHC (fro) FACS IP Rat IgG2a Log in to see YTS213-1 2
0.000883884 ABIN2478882 IHC (fro) FACS IP Rat IgG2a Log in to see YTS213-1 2
0.000883884 ABIN2610764 IHC (fro) FACS IP WB Biotin Rat IgG2a Log in to see C71-16

Top referenced anti-Integrin beta 2 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-Integrin beta 2 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 6 Antibodies
ELISA 21 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 126 Antibodies
Functional Studies (Func) 17 Antibodies
Immunoassay (IA) 1 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 15 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 34 Antibodies
Immunohistochemistry (IHC) 60 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 2 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 2 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 25 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 26 Antibodies
Immunoprecipitation (IP) 76 Antibodies
Intracellular Flow Cytometry (ICFC) 3 Antibodies
Mass Cytometry (CyTOF) 1 Antibodies
Neutralization (Neut) 2 Antibodies

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Reactivity Mouse (Murine)
(467), (208), (111), (39), (39), (21), (20), (14), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Host Rat
(363), (186), (155), (5), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 2 antibody is un-conjugated
(92), (77), (53), (19), (14), (11), (9), (8), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(497), (275), (273), (158), (105), (104), (84), (61), (44), (34), (20), (9), (7), (6), (5), (3), (2), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 Antibody (ABIN118151) Images
Specificity This antibody is specific for the common β2subunit of LFA-1 (CD11a/CD18), MAC-1 (CD11b/CD18) and P150,95 (CD11c/CD18) (2,3). These three β2 integrins, which function in cell-cell adhesion in the immune system, are also known as leukocyte integrins because their expression is limited to leukocytes (2,3).
Purification Purified
Immunogen Cell membrane glycoproteins derived from BW5147 cells (1)
Clone C71-16
Isotype IgG2a

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 Antibody (ABIN118151) Images back to top
Antigen
Alternative Name CD18 / ITGB2 (ITGB2 Antibody Abstract)
Background CD18 is an integrin. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA1, and combines with the alpha M chain to form the integrin Mac1. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling. CD18 is expressed by most leucocytes. Defects in the CD18 gene result in leukocyte adhesion deficiency.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
Gene ID 16414
NCBI Accession NP_032430
UniProt P11835
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 Antibody (ABIN118151) Images back to top
Application Notes IHC on acetone-fixed frozen sections. Immunoprecipitation. Flow cytometry (please see protocol for details).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 Antibody (ABIN118151) Images back to top
Concentration 0.2 mg/mL
Buffer PBS and 0.02 % sodium azide (NaN3)
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. Dilute only prior to immediate use
Storage 4 °C/-20 °C
Storage Comment Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Integrin beta 2 Antibody (ABIN118151)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Background publications

Springer: "Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm." in: Cell, Vol. 76, Issue 2, pp. 301-14, 1994

Larson, Springer: "Structure and function of leukocyte integrins." in: Immunological reviews, Vol. 114, pp. 181-217, 1990

Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, 1990

Springer, Davignon, Ho, Kürzinger, Martz, Sanchez-Madrid: "LFA-1 and Lyt-2,3, molecules associated with T lymphocyte-mediated killing; and Mac-1, an LFA-1 homologue associated with complement receptor function." in: Immunological reviews, Vol. 68, pp. 171-95, 1983

Trowbridge, Omary: "Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1." in: The Journal of experimental medicine, Vol. 154, Issue 5, pp. 1517-24, 1982