anti-Rat (Rattus) Integrin beta 2 antibody for Immunohistochemistry (Zinc-fixed Sections)

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • ITGB2
  • 2E6
  • AI528527
  • Cd18
  • LAD
  • LCAMB
  • Lfa1
  • MF17
  • CD18
  • LFA-1
  • MAC-1
  • MFI7
  • AI256028
  • LTbetaR
  • Ltar
  • TNF-R-III
  • TNFCR
  • TNFR-RP
  • TNFR2-RP
  • TNFRrp
  • Tnfbr
  • Tnfrsf3
  • D12S370
  • LT-BETA-R
  • TNFR3
  • TNFRSF3
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
  • integrin, beta 2
  • integrin beta 2
  • lymphotoxin B receptor
  • lymphotoxin beta receptor (TNFR superfamily, member 3)
  • ITGB2
  • Itgb2
  • CD18
  • Ltbr
  • LTBR
Reactivity
Rat (Rattus)
491
216
117
44
26
21
21
5
4
3
3
3
3
3
2
1
1
1
Host
Mouse
361
165
162
15
3
1
Clonality
Monoclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
88
74
53
20
15
12
9
8
8
7
7
7
6
6
6
6
5
5
5
5
4
3
3
3
3
3
3
3
3
2
2
2
1
1
Application
Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunoprecipitation (IP)
487
291
202
147
94
90
75
68
53
40
28
17
11
9
7
7
6
1
1
1
1
1
1
1
1
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Catalog No. ABIN1177020
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2689034 BR IHC (fro) FACS IHC (zinc) IP Mouse IgG1, kappa Log in to see WT-3 2

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Reactivity Rat (Rattus)
(491), (216), (117), (44), (26), (21), (21), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1)
Host Mouse
(361), (165), (162), (15), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 2 antibody is un-conjugated
(88), (74), (53), (20), (15), (12), (9), (8), (8), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1)
Application Blocking Reagent (BR), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc)), Immunoprecipitation (IP)
(487), (291), (202), (147), (94), (90), (75), (68), (53), (40), (28), (17), (11), (9), (7), (7), (6), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1177020) Images
Brand BD Pharmingen™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen PHA-stimulated rat splenocytes and rat thymic lymphoma FTL-43
Clone WT-3
Isotype IgG1, kappa

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1177020) Images back to top
Antigen
Alternative Name CD18 (ITGB2 Antibody Abstract)
Background The WT.3 antibody reacts with the 95-100 kDa beta2 subunit (CD18), which is found on the majority of leukocytes as a heterodimer with any of the three distinct CD11 alpha integrin subunits (CD11a or alphaL, CD11b or alphaM, CD11c or alphaX) to form, respectively, LFA-1, Mac-1, and gp150, 95. The function-blocking activity of WT.3 antibody has been determined in several in vitro assays measuring the binding of LFA-1 (alphaLbeta2 integrin) to ICAM-1 (CD54). It has also been reported that WT.3 mAb inhibits leukocyte infiltration in an in vivo system.
Synonyms: Integrin beta2 chain
Research Area Surface Receptors of Immune Cells
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 antibody (ABIN1177020) Images back to top
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 antibody (ABIN1177020) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Preservative Azide free
Storage 4 °C
Storage Comment Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-Integrin beta 2 antibody (ABIN1177020)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Product cited in:

Yamazaki, Seko, Tamatani, Miyasaka, Yagita, Okumura, Nagai, Yazaki: "Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules." in: The American journal of pathology, Vol. 143, Issue 2, pp. 410-8, 1993

Tamatani, Kotani, Miyasaka: "Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies." in: European journal of immunology, Vol. 21, Issue 3, pp. 627-33, 1991