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anti-Human IRAK4 antibody for Enzyme Immunoassay

Recommended IRAK4 Antibody (supplied by: Log in to see )

Antigen
Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies
  • zgc:55553
  • IRAK4
  • ipd1
  • irak-4
  • ny-ran-64
  • ny-ren-64
  • ren64
  • irak4
  • IPD1
  • IRAK-4
  • NY-REN-64
  • REN64
  • 8430405M07Rik
  • 9330209D03Rik
  • interleukin-1 receptor-associated kinase 4
  • Interleukin-1 receptor-associated kinase 4
  • IRAK4
  • irak4
  • LOC100227974
  • Irak4
Epitope
N-Term, AA 32-60
38
31
16
15
15
14
14
6
6
5
5
5
5
5
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
188
55
26
13
4
4
3
3
2
2
2
1
1
Host
Rabbit
140
32
24
Clonality
Polyclonal
Conjugate
This IRAK4 antibody is un-conjugated
9
8
7
6
5
5
4
3
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
147
89
27
26
26
11
11
8
7
5
3
2
2
1
1
1
Supplier
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Catalog No. ABIN952943
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN374511 EIA WB Goat N-Term Log in to see Polyclonal 1
1 ABIN401362 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 7
1 ABIN500044 EIA IF WB Rabbit IgG Log in to see Polyclonal 2
1 ABIN615818 EIA IHC (p) WB Goat N-Term Log in to see Polyclonal
1 ABIN1107881 EIA IHC (p) WB Mouse IgG1 Log in to see 2H9

Top referenced anti-IRAK4 antibody for Enzyme Immunoassay

Similar anti-IRAK4 Antibodies

Application / Reactivity Human
Dot Blot (DB) 1 Antibodies
ELISA 83 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 8 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 11 Antibodies
Immunofluorescence (IF) 11 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 26 Antibodies
Immunohistochemistry (IHC) 25 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 26 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Intracellular Staining (ICS) 2 Antibodies
Western Blotting (WB) 140 Antibodies

General

Antigen Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antibodies
Epitope N-Term, AA 32-60
(38), (31), (16), (15), (15), (14), (14), (6), (6), (5), (5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(188), (55), (26), (13), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(140), (32), (24)
Clonality
Polyclonal
Conjugate This IRAK4 antibody is un-conjugated
(9), (8), (7), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(147), (89), (27), (26), (26), (11), (11), (8), (7), (5), (3), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-IRAK4 Antibody

Target Details IRAK4 Application Details Handling References for anti-IRAK4 Antibody (ABIN952943) Images
Specificity This antibody recognizes Human IRAK4 (N-term).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 32-60 amino acids from the N-terminal region of Human IRAK4.
Isotype Ig

Target Details IRAK4

Product Details anti-IRAK4 Antibody Application Details Handling References for anti-IRAK4 Antibody (ABIN952943) Images back to top
Antigen
Alternative Name IRAK4 (IRAK4 Antibody Abstract)
Background This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: IRAK-4, Interleukin-1 receptor-associated kinase-like, NY-REN-64
Molecular Weight 51530 Da
Gene ID 51135
NCBI Accession NP_001107654
Research Area Immunology, Innate Immunity, Atherosclerosis, Cytokines, Receptors, Inflammation
Pathways NF-kappaB Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-IRAK4 Antibody Target Details IRAK4 Handling References for anti-IRAK4 Antibody (ABIN952943) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details References for anti-IRAK4 Antibody (ABIN952943) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-IRAK4 Antibody (ABIN952943)

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Handling Images back to top
Background publications

McDonald, Goldman, Gomez-Duarte, Issekutz, Kumararatne, Doffinger, Geha: "Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients." in: The Journal of allergy and clinical immunology, Vol. 126, Issue 2, pp. 332-7, 337.e1-2, 2010

Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, 2010

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Schuurhof, Bont, Siezen, Hodemaekers, van Houwelingen, Kimman, Hoebee, Kimpen, Janssen: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, 2010

Hilgers, Teixeira, Parker: "Translation-independent inhibition of mRNA deadenylation during stress in Saccharomyces cerevisiae." in: RNA (New York, N.Y.), Vol. 12, Issue 10, pp. 1835-45, 2006

Images

Product Details anti-IRAK4 Antibody Target Details IRAK4 Application Details Handling References for anti-IRAK4 Antibody (ABIN952943) back to top
Supplier Images
Western Blotting (WB) image for anti-IRAK4 antibody (Interleukin-1 Receptor-Associated Kinase 4) (N-Term) (ABIN952943) Western blot analysis of IRAK4 Antibody (N-term) in NCI-H460 cell line lysates (35ug/...