|Application / Reactivity||Mouse (Murine)|
|Enzyme Immunoassay (EIA)||2 Antibodies|
|Flow Cytometry (FACS)||51 Antibodies|
|Functional Studies (Func)||15 Antibodies|
|Immunocytochemistry (ICC)||2 Antibodies|
|Immunofluorescence (IF)||5 Antibodies|
|Immunohistochemistry (IHC)||6 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||1 Antibodies|
|Immunoprecipitation (IP)||1 Antibodies|
|Neutralization (Neut)||4 Antibodies|
|Western Blotting (WB)||33 Antibodies|
|Antigen||Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) Antibodies|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This LTBR antibody is conjugated to PE Alternatives|
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
|6 references available|
|Supplier||Log in to see|
Product Details anti-LTBR AntibodyTarget Details LTBR Application Details Handling References for anti-LTBR Antibody (ABIN2663836) Images
|Purification||The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.|
Target Details LTBRProduct Details anti-LTBR Antibody Application Details Handling References for anti-LTBR Antibody (ABIN2663836) Images back to top
|Alternative Name||Lymphotoxin beta Receptor (LTBR Antibody Abstract)|
|Background||LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.|
Application DetailsProduct Details anti-LTBR Antibody Target Details LTBR Handling References for anti-LTBR Antibody (ABIN2663836) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-LTBR Antibody Target Details LTBR Application Details References for anti-LTBR Antibody (ABIN2663836) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Protect from prolonged exposure to light. Do not freeze.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-LTBR Antibody (ABIN2663836)Product Details anti-LTBR Antibody Target Details LTBR Application Details Handling Images back to top
Dejardin, Droin, Delhase et al.: "The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways." in: Immunity, Vol. 17, Issue 4, pp. 525-35, 2002 (PubMed).
Tamada, Shimozaki, Chapoval et al.: "LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 8, pp. 4105-10, 2000 (PubMed).
Fütterer, Mink, Luz et al.: "The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues." in: Immunity, Vol. 9, Issue 1, pp. 59-70, 1998 (PubMed).
Browning, Sizing, Lawton et al.: "Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 7, pp. 3288-98, 1997 (PubMed).
Nakamura, Tashiro, Nazarea et al.: "The murine lymphotoxin-beta receptor cDNA: isolation by the signal sequence trap and chromosomal mapping." in: Genomics, Vol. 30, Issue 2, pp. 312-9, 1996 (PubMed).
Force, Walter, Hession et al.: "Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 11, pp. 5280-8, 1995 (PubMed).
ImagesProduct Details anti-LTBR Antibody Target Details LTBR Application Details Handling References for anti-LTBR Antibody (ABIN2663836) back to top