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Browse our anti-MAP3K7 (MAP3K7) Antibodies

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 Antibodies (MAP3K7)
On www.antibodies-online.com are 182 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies from 15 different suppliers available. Additionally we are shipping MAP3K7 Kits (10) and MAP3K7 Proteins (6) and many more products for this protein. A total of 217 MAP3K7 products are currently listed.
Synonyms:
B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612
list all antibodies Gene Name GeneID UniProt
MAP3K7 313121 P0C8E4
MAP3K7 6885 O43318
MAP3K7 26409 Q62073

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Most Popular Reactivities for anti-MAP3K7 (MAP3K7) Antibodies

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anti-Rat (Rattus) MAP3K7 Antibodies:

anti-Human MAP3K7 Antibodies:

anti-Mouse (Murine) MAP3K7 Antibodies:

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Top referenced anti-MAP3K7 Antibodies

  1. Human Polyclonal MAP3K7 Primary Antibody for EIA - ABIN358291 : Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta. in Biochemical and biophysical research communications 2003 (PubMed)
    Show all 5 references for ABIN358291

  2. Human Polyclonal MAP3K7 Primary Antibody for EIA, IHC (p) - ABIN360354 : Takaesu, Surabhi, Park, Ninomiya-Tsuji, Matsumoto, Gaynor: TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. in Journal of molecular biology 2003 (PubMed)
    Show all 5 references for ABIN360354

  3. Human Polyclonal MAP3K7 Primary Antibody for DB, EIA - ABIN358312 : Smit, Baas, Kuipers, Korswagen, van de Wetering, Clevers: Wnt activates the Tak1/Nemo-like kinase pathway. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358312

  4. Human Polyclonal MAP3K7 Primary Antibody for ELISA, WB - ABIN185640 : Omori, Matsumoto, Sanjo, Sato, Akira, Smart, Ninomiya-Tsuji: TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. in The Journal of biological chemistry 2006 (PubMed)
    Show all 2 references for ABIN185640

  5. Human Polyclonal MAP3K7 Primary Antibody for IHC, ELISA - ABIN1532056 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for ABIN1532056

  6. Human Polyclonal MAP3K7 Primary Antibody for ELISA, WB - ABIN1532055 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 2 references for ABIN1532055

  7. Human Polyclonal MAP3K7 Primary Antibody for EIA, WB - ABIN500865 : Yamaguchi, Shirakabe, Shibuya, Irie, Oishi, Ueno, Taniguchi, Nishida, Matsumoto: Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. in Science (New York, N.Y.) 1996 (PubMed)

More Antibodies against MAP3K7 Interaction Partners

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. Loss of MAP3K7 are associated with esophageal squamous cell carcinoma.

  2. This paper highlights that targeting the BMP and TGFbeta (show TGFB1 Antibodies) type I and type II receptors causes a downregulation of XIAP (show XIAP Antibodies), TAK1, and Id1 (show ID1 Antibodies) leading to cell death of lung cancer cells.

  3. Polyubiquitination of Transforming Growth Factor beta-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4 (show TLR4 Antibodies)-mediated JNK (show MAPK8 Antibodies) and p38 MAPK (show MAPK14 Antibodies) Activation

  4. The data emphasize the central role of TAK1 in controlling signaling cascades and functional responses in primary neutrophils, making it a promising target for therapeutic intervention in view of the role of neutrophils in chronic inflammatory conditions.

  5. MiR (show MLXIP Antibodies)-377 is an important negative regulator of E2F (show E2F1 Antibodies) and MAP3K7/NF-kB signaling pathway in melanoma cells.

  6. the TAK1 signaling pathway may represent a suitable target to design new, antifibrotic therapies

  7. Findings indicate that SHIP2 (show INPPL1 Antibodies) is a regulator of lymphatic function in humans and that inherited mutations in the INPPL1 (show INPPL1 Antibodies) gene may act in concert with HGF (show HGF Antibodies), and likely MAP3K7, mutations to exacerbate lymphatic phenotypes.

  8. Data indicate that inhibition of TGF-beta (show TGFB1 Antibodies)-activated protein kinase (show CDK7 Antibodies) 1 (TAK1) reduces chemokine (C-C motif) receptor 7 (CCR7 (show CCR7 Antibodies)) expression.

  9. identify coordinate loss of MAP3K7 and CHD1 (show CHD1 Antibodies) as a unique driver of aggressive prostate cancer development

  10. Data indicate 4-substituted 1H-pyrrolo[2,3-b]pyridines as potent inhibitors against TGFbeta (show TGFB1 Antibodies)-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2 (show MAP4K2 Antibodies)).

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) interaction partners

  1. Data show that TGFbeta (show TGFB1 Antibodies)-activated kinase-1 (TAK1 (show NR2C2 Antibodies)) activated nuclear factor of activated T-cells (NFAT (show NFATC1 Antibodies))/NF-kappa B (NFkappaB (show NFKB1 Antibodies)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (show BNIP3 Antibodies)), and inhibited cardiac cell death.

  2. Crucial functions of inflammatory TAK1 (show NR2C2 Antibodies)-NEMO (show IKBKG Antibodies) signaling in protecting the brain endothelium and maintaining normal brain function.

  3. Roles of TAK1 (show NR2C2 Antibodies) in vascular oxidative stress and its contribution to neointima formation after vascular injury.

  4. Inactivation of TAK1 (show NR2C2 Antibodies) in satellite cells inhibits muscle regeneration in adult mice.

  5. our current study highlighted the emerging role of TAK1 (show NR2C2 Antibodies) in configuring the gut (show GUSB Antibodies)-specialized T cell subset, which regulates mucosal homeostasis under lymphopenic conditions.

  6. the ADAP (show APP Antibodies) CARMA1 (show CARD11 Antibodies) binding site is required for IKK gamma (show IKBKG Antibodies) ubiquitination; both TAK1 (show NR2C2 Antibodies) and CARMA1 (show CARD11 Antibodies) binding sites are required for IkappaB alpha (show NFKBIA Antibodies) phosphorylation and degradation and NF-kappaB (show NFKB1 Antibodies) nuclear translocation

  7. Results provide evidence that TAK1 (show NR2C2 Antibodies) is required for the activation of NF-kappaB (show NFKB1 Antibodies) in thymocytes and suggest that TAK1 (show NR2C2 Antibodies) plays a central role in both innate and adaptive immunity.

  8. TAK1 (show NR2C2 Antibodies) is essential for connective tissue deposition in the dermis.

  9. Tak1 functions to regulate tongue development by controlling Fgf10 expression and could represent a candidate gene for mutation in human PRS clefting.

  10. In vivo knockdown of TAK1 (show NR2C2 Antibodies) accelerates bone marrow proliferation/differentiation and induces systemic inflammation.

MAP3K7 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

  • mitogen activated protein kinase kinase kinase 7 (map3k7) antibody
  • mitogen activated protein kinase kinase kinase 7 (Map3k7) antibody
  • mitogen-activated protein kinase kinase kinase 7 (MAP3K7) antibody
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7) antibody
  • B430101B05 antibody
  • C87327 antibody
  • MEKK7 antibody
  • si:ch211-225h9.1 antibody
  • TAK1 antibody
  • TGF1a antibody
  • zgc:110612 antibody

Protein level used designations for MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID SPECIES
553788 Danio rerio
313121 Rattus norvegicus
6885 Homo sapiens
26409 Mus musculus
529146 Bos taurus
100171454 Pongo abelii
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