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anti-Human MAP3K7 antibody for Enzyme Immunoassay

Recommended MAP3K7 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
  • si:ch211-225h9.1
  • zgc:110612
  • Tak1
  • MEKK7
  • TAK1
  • TGF1a
  • B430101B05
  • C87327
  • mitogen activated protein kinase kinase kinase 7
  • mitogen-activated protein kinase kinase kinase 7
  • map3k7
  • Map3k7
  • MAP3K7
Epitope
C-Term
30
17
17
14
13
13
10
9
6
6
5
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
172
71
58
6
6
5
5
5
5
4
3
2
2
2
2
1
1
Host
Rabbit
149
13
12
Clonality
Polyclonal
Conjugate
This MAP3K7 antibody is un-conjugated
9
9
9
9
9
9
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
143
103
49
35
17
6
5
4
2
1
1
1
1
Supplier
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Catalog No. ABIN360354
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN358312 DB EIA Rabbit Ig pSer192 Log in to see Polyclonal 5
1 ABIN358291 EIA Rabbit Ig Thr187, pThr187 Log in to see Polyclonal 5
1 ABIN500865 EIA WB Rabbit IgG N-Term Log in to see Polyclonal 1
1 ABIN784213 EIA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal

Top referenced anti-MAP3K7 antibody for Enzyme Immunoassay

Similar anti-MAP3K7 Antibodies

Application / Reactivity Human
Dot Blot (DB) 35 Antibodies
ELISA 103 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunohistochemistry (IHC) 48 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 17 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
RNA Interference (RNAi) 1 Antibodies
Western Blotting (WB) 142 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
Epitope C-Term
(30), (17), (17), (14), (13), (13), (10), (9), (6), (6), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(172), (71), (58), (6), (6), (5), (5), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(149), (13), (12)
Clonality
Polyclonal
Conjugate This MAP3K7 antibody is un-conjugated
(9), (9), (9), (9), (9), (9)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(143), (103), (49), (35), (17), (6), (5), (4), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-MAP3K7 Antibody

Target Details MAP3K7 Application Details Handling References for anti-MAP3K7 Antibody (ABIN360354) Images
Specificity This antibody reacts to TAK1.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human TAK1.
Isotype Ig

Target Details MAP3K7

Product Details anti-MAP3K7 Antibody Application Details Handling References for anti-MAP3K7 Antibody (ABIN360354) Images back to top
Antigen
Alternative Name TAK1 / MAP3K7 (MAP3K7 Antibody Abstract)
Background TAK1 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.Synonyms: Mitogen-activated protein kinase kinase kinase 7, TAK-1, TAK1, TGF-beta-activated kinase 1, Transforming growth factor-beta-activated kinase 1
Gene ID 6885, 9606
UniProt O43318
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades

Application Details

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Handling References for anti-MAP3K7 Antibody (ABIN360354) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details References for anti-MAP3K7 Antibody (ABIN360354) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MAP3K7 Antibody (ABIN360354)

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Handling Images back to top
Background publications

Takaesu, Surabhi, Park, Ninomiya-Tsuji, Matsumoto, Gaynor: "TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway." in: Journal of molecular biology, Vol. 326, Issue 1, pp. 105-15, 2003

Cheung, Campbell, Nebreda, Cohen: "Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha." in: The EMBO journal, Vol. 22, Issue 21, pp. 5793-805, 2003

Sakurai, Suzuki, Kawasaki, Nakano, Okazaki, Chino, Doi, Saiki: "Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36916-23, 2003

Ono, Ohtomo, Ninomiya-Tsuji, Tsuchiya: "A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta." in: Biochemical and biophysical research communications, Vol. 307, Issue 2, pp. 332-7, 2003

Edlund, Bu, Schuster, Aspenström, Heuchel, Heldin, ten Dijke, Heldin, Landström et al.: "Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase ..." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 529-44, 2003

Images

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Supplier Images
 image for anti-MAP3K7 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 7) (C-Term) (ABIN360354) anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (C-Term) antibody
 image for anti-MAP3K7 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 7) (C-Term) (ABIN360354) anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (C-Term) antibody (Image 2)