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anti-Rat (Rattus) MAP3K7 antibody for Enzyme Immunoassay

Recommended MAP3K7 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
  • si:ch211-225h9.1
  • zgc:110612
  • Tak1
  • MEKK7
  • TAK1
  • TGF1a
  • B430101B05
  • C87327
  • mitogen activated protein kinase kinase kinase 7
  • mitogen-activated protein kinase kinase kinase 7
  • map3k7
  • Map3k7
  • MAP3K7
Epitope
N-Term
28
17
17
14
13
11
10
9
6
6
5
4
4
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
167
67
55
6
6
5
5
5
5
4
3
2
2
2
2
1
1
Host
Rabbit
145
12
12
Clonality
Polyclonal
Conjugate
This MAP3K7 antibody is un-conjugated
9
9
9
9
9
9
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
138
102
48
35
17
6
5
4
1
1
1
1
Supplier
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Catalog No. ABIN500865
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN784213 EIA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal

Top referenced anti-MAP3K7 antibody for Enzyme Immunoassay

Similar anti-MAP3K7 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 137 Antibodies 64 Antibodies 52 Antibodies
RNA Interference (RNAi) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 6 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies 15 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 47 Antibodies 22 Antibodies 13 Antibodies

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
Epitope N-Term
(28), (17), (17), (14), (13), (11), (10), (9), (6), (6), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(167), (67), (55), (6), (6), (5), (5), (5), (5), (4), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(145), (12), (12)
Clonality
Polyclonal
Conjugate This MAP3K7 antibody is un-conjugated
(9), (9), (9), (9), (9), (9)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(138), (102), (48), (35), (17), (6), (5), (4), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-MAP3K7 Antibody

Target Details MAP3K7 Application Details Handling References for anti-MAP3K7 Antibody (ABIN500865) Images
Specificity This antibody detects TAK1 / MAP3K7 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Peptide affinity chromatography
Immunogen Human TAK1 / MAP3K7 (N-Terminus) Peptide
Isotype IgG

Target Details MAP3K7

Product Details anti-MAP3K7 Antibody Application Details Handling References for anti-MAP3K7 Antibody (ABIN500865) Images back to top
Antigen
Alternative Name TAK1 / MAP3K7 (MAP3K7 Antibody Abstract)
Background TAK1 (TGF-β activated protein kinase 1) is a widely expressed enzyme originally identified as a mitogen-activated protein kinase kinase kinase (MAP3K7) (1). It has since been shown to mediate various intracellular signaling pathways, such as those induced by TGF-Β and members of the Toll-IL-1R (TIR) superfamily (2), thus acting as an intermediate in both proliferative and innate and adaptive immune responses (3). TAK1 is normally present in cells in a complex with TAK1-binding protein 1 (TAB1) and either TAB2 or TAB3 (4,5). Association with TAB1 triggers TAK1 kinase activity by inducing TAK1 autophosphorylation (6), while TAB2 and possibly TAB3 may contribute to SAPK2a/p38a-mediated feedback inhibition of TAK1 activity (5).Synonyms: Mitogen-activated protein kinase kinase kinase 7, TAK-1, TAK1, TGF-beta-activated kinase 1, Transforming growth factor-beta-activated kinase 1
Gene ID 6885
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades

Application Details

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Handling References for anti-MAP3K7 Antibody (ABIN500865) Images back to top
Application Notes ELISA. Western blot: 0.5 to 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details References for anti-MAP3K7 Antibody (ABIN500865) Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

References for anti-MAP3K7 Antibody (ABIN500865)

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Handling Images back to top
Background publications

Yamaguchi, Shirakabe, Shibuya, Irie, Oishi, Ueno, Taniguchi, Nishida, Matsumoto: "Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction." in: Science (New York, N.Y.), Vol. 270, Issue 5244, pp. 2008-11, 1996

Images

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Handling References for anti-MAP3K7 Antibody (ABIN500865) back to top
Supplier Images
Western Blotting (WB) image for anti-MAP3K7 antibody (Mitogen-Activated Protein Kinase Kinase Kinase 7) (N-Term) (ABIN500865) Western blot analysis of TAK1 in Rat thymus cell lysate with this product at (A) 1, (...