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Browse our anti-MYD88 (MYD88) Antibodies

Full name:
anti-Myeloid Differentiation Primary Response Gene (88) Antibodies (MYD88)
On www.antibodies-online.com are 258 Myeloid Differentiation Primary Response Gene (88) (MYD88) Antibodies from 35 different suppliers available. Additionally we are shipping MYD88 Kits (25) and MYD88 Proteins (23) and many more products for this protein. A total of 327 MYD88 products are currently listed.
Synonyms:
CG2078, Dmel\\CG2078, DmMyd88, dMyd88, EP(2)2535, GB12344, irak-2, kra, LD20892, MGC84928, myd88, MYD88D, Myd88F, NV10640, XMyD88, zgc:103541
list all antibodies Gene Name GeneID UniProt
MYD88 4615 Q99836
MYD88 301059 Q6Y1S1
MYD88 17874 P22366

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Most Popular Reactivities for anti-MYD88 (MYD88) Antibodies

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Top referenced anti-MYD88 Antibodies

  1. Human Polyclonal MYD88 Primary Antibody for EIA, WB - ABIN401364 : Adachi, Kawai, Takeda, Matsumoto, Tsutsui, Sakagami, Nakanishi, Akira: Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. in Immunity 1998 (PubMed)
    Show all 5 references for ABIN401364

  2. Human Polyclonal MYD88 Primary Antibody for EIA, WB - ABIN500302 : Medzhitov, Preston-Hurlburt, Kopp, Stadlen, Chen, Ghosh, Janeway: MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. in Molecular cell 1998 (PubMed)
    Show all 4 references for ABIN500302

  3. Human Polyclonal MYD88 Primary Antibody for EIA, WB - ABIN453754 : Bannon, Davies, Collett, Warhurst: Potentiation of flagellin responses in gut epithelial cells by interferon-gamma is associated with STAT-independent regulation of MyD88 expression. in The Biochemical journal 2009 (PubMed)
    Show all 2 references for ABIN453754

  4. Human Polyclonal MYD88 Primary Antibody for EIA, IHC (p) - ABIN500300 : Muzio, Ni, Feng, Dixit: IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 2 references for ABIN500300

  5. Human Monoclonal MYD88 Primary Antibody for FACS, IF - ABIN2453996 : Choi, Kim, Lee, Kim: MYD88 expression and L265P mutation in diffuse large B-cell lymphoma. in Human pathology 2013 (PubMed)
    Show all 2 references for ABIN2453996

  6. Human Polyclonal MYD88 Primary Antibody for FACS, IHC (p) - ABIN652460 : Deng, Yuan, Guo, Zhu, Pan, Liu: Efficacy of atorvastatin on hippocampal neuronal damage caused by chronic intermittent hypoxia: involving TLR4 and its downstream signaling pathway. in Respiratory physiology & neurobiology 2015 (PubMed)
    Show all 2 references for ABIN652460

  7. Chimpanzee Polyclonal MYD88 Primary Antibody for EIA, IHC (p) - ABIN374527 : Li, Qin: Modulation of Toll-interleukin 1 receptor mediated signaling. in Journal of molecular medicine (Berlin, Germany) 2005 (PubMed)

  8. Cow (Bovine) Polyclonal MYD88 Primary Antibody for WB - ABIN2786658 : Dhiman, Ovsyannikova, Vierkant, Ryan, Pankratz, Jacobson, Poland: Associations between SNPs in toll-like receptors and related intracellular signaling molecules and immune responses to measles vaccine: preliminary results. in Vaccine 2008 (PubMed)

More Antibodies against MYD88 Interaction Partners

Fruit Fly (Drosophila melanogaster) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. a novel function of MyD88 in the regulation of metabolism that appears to be independent of its known roles in immunity and development.

  2. propose that dMyD88 is the functional homolog of TIRAP (show TIRAP Antibodies) and that both proteins function as sorting adaptors to recruit downstream signaling adaptors to activated receptors

  3. DmMyD88 encodes an essential component of the Toll (show TLR4 Antibodies) pathway in dorsoventral pattern formation.

  4. We show that there is a direct interaction between Kra and Tube presumably mediated by the death domains present in both proteins.

  5. both the heterodimeric and heterotrimeric complexes form kidney-shaped structures and that Tube is bivalent and has separate high affinity binding sites for dMyD88 and Pelle (show IRAK1 Antibodies).

Zebrafish Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. Fish IRF6 (show IRF6 Antibodies) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 and TBK1 (show TBK1 Antibodies), suggesting that differences in the IRF6 (show IRF6 Antibodies) regulation pattern exist between lower and higher vertebrates.

  2. DrIRF1 works in concert with MyD88 to activate zebrafish IFNvarphi3 but not IFNvarphi1. These results provide insights into the evolving function of IRF1 (show IRF1 Antibodies) as a positive IFN regulator.

  3. MyD88 signaling has an important protective role during early pathogenesis.

  4. MyD88-dependent signaling is involved in the innate immune response of the developing zebrafish embryo, a model for the study of vertebrate innate immunity.

Human Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. In patient population from Southeast Serbia Myd 88 L265 mutation was not responsible for the development of diffuse large B-cell non Hodgkin lymphoma.

  2. FSTL1 (show FSTL1 Antibodies) displays anti-inflammatory effects against oxidized low-density lipoprotein-induced pro-inflammatory cytokine production via a mechanism that involves the TLR4 (show TLR4 Antibodies)/MyD88/NF-kappaB (show NFKB1 Antibodies) and MAPK (show MAPK1 Antibodies) signaling pathways.

  3. The incidence of MYD88 and CD79B (show CD79B Antibodies) mutations in patients with CD5 (show CD5 Antibodies)(+) DLBCL is lower than that in patients with DLBCL-SS, suggesting that CD5 (show CD5 Antibodies)(+) DLBCL is not the same disease as DLBCL-SS in terms of gene mutation status.

  4. NEDDylation of MyD88 regulates NF-kappaB (show NFKB1 Antibodies) activity through antagonizing its ubiquitination, suggesting a novel mechanism of modulating NF-kappaB (show NFKB1 Antibodies) signaling pathway.

  5. analysis of sudden infant death syndrome brains shows downregulation of MyD88 in tissue from SIDS (show IDS Antibodies) brains, as well as the downregulation of the genes encoding CCL3 (show CCL3 Antibodies) and UNC13 (show UNC13B Antibodies) in the liver

  6. homo-dimerization and restrains the dynamics of the MyD88-TIR domain

  7. Epistatic interaction between MyD88 and TIRAP (show TIRAP Antibodies) against Helicobacter pylori.

  8. It was found that HP1437 forms dimers in solution similar to other bacterial Toll (show TLR4 Antibodies)/IL-1 (show IL1A Antibodies) receptor domain proteins. Furthermore, glutathione S-transferase (show GSTa2 Antibodies) pull down assays identified an interaction between HP1437 and human Toll (show TLR4 Antibodies)/IL-1 (show IL1A Antibodies) receptor domain adaptor MyD88.

  9. Findings suggest that high mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling pathway may contribute to the development and progression of gastric cancer via the nuclear factor kappa B pathway.

  10. Non-IgM Lymphoplasmacytic lymphomas are a clinically and pathologically heterogeneous group and often harbor MYD88 L265P mutation

Pig (Porcine) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. These results suggest that porcine circovirus 2 induces IL-8 (show IL8 Antibodies) secretion via the TLR2 (show TLR2 Antibodies)/MyD88/NF-kappaB (show NFKB1 Antibodies) signalling pathway.

  2. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for MyD88.

  3. These results suggest that an MyD88-dependent signaling pathway is present in newborn as well as in adult swine and that it is involved in the innate immune system of these animals.

Cow (Bovine) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. L. rhamnosus GR-1 ameliorates the E. coli-induced disruption of cellular ultrastructure, subsequently reducing the percentage of bovine endometrial epithelial cells apoptosis and limiting inflammatory responses, partly via attenuation of MyD88-dependent and MyD88-independent pathway activation

  2. Modulated cytokine expression in Bovine viral diarrhea virus type 2 infected macrophages was associated with decreased MyD88 expression.

  3. The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis.

  4. MyD88 plays a functional role in transducing LPS (show IRF6 Antibodies) signaling from TLR-4 (show TLR4 Antibodies) to downstream effector molecules involved in NF-kappaB (show NFKB1 Antibodies) activation

Atlantic Salmon (Salmo salar) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. MyD88 interacts with interferon (show IFNA Antibodies) regulatory factor (IRF) 3 (show IRF3 Antibodies) and IRF7 (show IRF7 Antibodies) in Atlantic salmon (Salmo salar)

  2. the salmon MyD88 was cloned and its expression was analysed.

Mouse (Murine) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. this study shows that MyD88-dependent mechanisms are critical for orchestrating lung inflammatory responses, in terms of IL-17A (show IL17A Antibodies) production, as well as eosinophil and neutrophil recruitment

  2. a deficiency in MyD88 or CybB (show CYBB Antibodies) is associated with impaired bacterial clearance and increased granuloma formation in the lung.

  3. TLR3 (show TLR3 Antibodies), 7, and/or 9, but not TLR2 (show TLR2 Antibodies) or 4, also were required extrinsically for MyD88-dependent Th17 cell responses and vaccine immunity.

  4. These findings demonstrate that PGN (show SPG7 Antibodies) promotes the secretion of G-CSF (show CSF3 Antibodies) from monocytes and endothelial cells, leading to the acceleration of granulopoiesis. Our results illustrate that bacterial recognition by TLR2 (show TLR2 Antibodies) facilitates granulopoiesis during Gram-positive bacterial infection.

  5. MyD88-dependent signaling contributes to the inflammatory responses induced by cerebral ischemia/reperfusion injury.

  6. this paper shows that genetic ablation of innate immunological sensing dependent on the adaptor MyD88 in CCL19 (show CCL19 Antibodies)-expressing fibroblastic reticular cells precipitates severe intestinal inflammatory disease in the aftermath of infection with an enteropathogenic virus

  7. Pharmacological inhibition of MyD88 signaling by novel inhibitor TJ-M2010-5 shows a powerful anti-rejection effect in mouse heart and skin transplantation models.

  8. Studies indicate that SHP1 (show PTPN6 Antibodies) and SYK (show SYK Antibodies) crosstalk as a critical regulator of MyD88 post-translational modifications and IL-1 (show IL1A Antibodies)-driven inflammation.

  9. Early clearance of P. aeruginosa from the airways is dependent on flagellin (show FliC Antibodies)-TLR5 (show TLR5 Antibodies)-MyD88-dependent signaling in respiratory epithelial cells.

  10. the role of Toll (show TLR4 Antibodies)-like receptor (TLR) 2 (show TLR2 Antibodies), TLR4 (show TLR4 Antibodies), myeloid differentiation response gene 88, and Toll (show TLR4 Antibodies)-IL-1 (show IL1A Antibodies) receptor domain-containing adaptor-inducing interferon-gamma (show IFNG Antibodies) (TRIF (show RNF138 Antibodies)), factors critically involved in the TLR signaling pathway, was studied in experimental autoimmune neuritis.

MYD88 Antigen Profile

Antigen Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MYD88

  • myeloid differentiation primary response gene (88) (myd88-b) antibody
  • CG2078 gene product from transcript CG2078-RB (Myd88) antibody
  • myeloid differentiation primary response gene (88) (myd88) antibody
  • myeloid differentiation primary response factor 88 (Myd88) antibody
  • myeloid differentiation primary response 88 (myd88) antibody
  • myeloid differentiation primary response gene 88 (Myd88) antibody
  • MyD88 adaptor (myd88) antibody
  • myeloid differentiation factor 88 (myd88) antibody
  • myeloid differentiation response protein 88 (myd88) antibody
  • myeloid differentiation primary response gene 88 (myd88) antibody
  • interleukin-1 receptor-associated kinase 2 (IRAK2) antibody
  • interleukin-1 receptor-associated kinase 2 (irak2) antibody
  • interleukin-1 receptor-associated kinase 2 (LOC100228175) antibody
  • myeloid differentiation primary response 88 (MYD88) antibody
  • myeloid differentiation primary response 88 (Myd88) antibody
  • myeloid differentiation primary response gene (88) (MYD88) antibody
  • CG2078 antibody
  • Dmel\\CG2078 antibody
  • DmMyd88 antibody
  • dMyd88 antibody
  • EP(2)2535 antibody
  • GB12344 antibody
  • irak-2 antibody
  • kra antibody
  • LD20892 antibody
  • MGC84928 antibody
  • myd88 antibody
  • MYD88D antibody
  • Myd88F antibody
  • NV10640 antibody
  • XMyD88 antibody
  • zgc:103541 antibody

Protein level used designations for MYD88

myeloid differentiation primary response protein MyD88-B , Toll/IL-1 receptor binding protein MyD88-B , CG2078-PA , CG2078-PB , Myd88-PA , Myd88-PB , Myd88F , krapfen , myeloid differentiation primary response factor 88 , myeloid differentiation primary response protein MyD88 , zMyD88 , myeloid differentiation primary response gene (88) , myeloid differentiation primary response gene 88 , myeloid differentiation factor 88 , myeloid differentiation response protein 88 , interleukin-1 receptor-associated kinase-like 2 , interleukin-1 receptor-associated kinase 2 , myeloid differentiation primary response protein 88

GENE ID SPECIES
734302 Xenopus laevis
35956 Drosophila melanogaster
403145 Danio rerio
413194 Apis mellifera
549591 Xenopus (Silurana) tropicalis
100118553 Nasonia vitripennis
100134853 Takifugu rubripes
100136123 Oncorhynchus mykiss
100305041 Ictalurus punctatus
100616081 Amphimedon queenslandica
416118 Gallus gallus
493227 Xenopus (Silurana) tropicalis
100228175 Taeniopygia guttata
4615 Homo sapiens
301059 Rattus norvegicus
477024 Canis lupus familiaris
460269 Pan troglodytes
420420 Gallus gallus
396646 Sus scrofa
444881 Bos taurus
678682 Ovis aries
696494 Macaca mulatta
100169859 Salmo salar
17874 Mus musculus
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