Browse our MYD88 (MYD88) ELISA Kits

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Myeloid Differentiation Primary Response Gene (88) ELISA Kits (MYD88)
On www.antibodies-online.com are 25 Myeloid Differentiation Primary Response Gene (88) (MYD88) ELISA Kits from 9 different suppliers available. Additionally we are shipping MYD88 Antibodies (267) and MYD88 Proteins (23) and many more products for this protein. A total of 336 MYD88 products are currently listed.
Synonyms:
CG2078, Dmel\\CG2078, DmMyd88, dMyd88, EP(2)2535, GB12344, irak-2, kra, LD20892, MGC84928, myd88, MYD88D, Myd88F, NV10640, XMyD88, zgc:103541
list all ELISA KIts Gene Name GeneID UniProt
MYD88 4615 Q99836
MYD88 301059 Q6Y1S1
MYD88 17874 P22366

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Top referenced MYD88 ELISA Kits

  1. Human MYD88 ELISA Kit for Sandwich ELISA - ABIN1672854 : Bonnert, Garka, Parnet, Sonoda, Testa, Sims: The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. in FEBS letters 1997 (PubMed)

More ELISA Kits for MYD88 Interaction Partners

Fruit Fly (Drosophila melanogaster) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. a novel function of MyD88 in the regulation of metabolism that appears to be independent of its known roles in immunity and development.

  2. propose that dMyD88 is the functional homolog of TIRAP (show TIRAP ELISA Kits) and that both proteins function as sorting adaptors to recruit downstream signaling adaptors to activated receptors

  3. DmMyD88 encodes an essential component of the Toll (show TLR4 ELISA Kits) pathway in dorsoventral pattern formation.

  4. We show that there is a direct interaction between Kra and Tube presumably mediated by the death domains present in both proteins.

  5. both the heterodimeric and heterotrimeric complexes form kidney-shaped structures and that Tube is bivalent and has separate high affinity binding sites for dMyD88 and Pelle (show IRAK1 ELISA Kits).

Zebrafish Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. Fish IRF6 (show IRF6 ELISA Kits) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 and TBK1 (show TBK1 ELISA Kits), suggesting that differences in the IRF6 (show IRF6 ELISA Kits) regulation pattern exist between lower and higher vertebrates.

  2. DrIRF1 works in concert with MyD88 to activate zebrafish IFNvarphi3 but not IFNvarphi1. These results provide insights into the evolving function of IRF1 (show IRF1 ELISA Kits) as a positive IFN regulator.

  3. MyD88 signaling has an important protective role during early pathogenesis.

  4. MyD88-dependent signaling is involved in the innate immune response of the developing zebrafish embryo, a model for the study of vertebrate innate immunity.

Human Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. Data indicate that 64 patients (57.1%) carried the myeloid differentiation factor 88 protein (MYD88) L265P mutation and 14 patients (12.5%) carried the chemokine (C-X-C motif) receptor 4 (CXCR4) WHIM (show CXCR4 ELISA Kits)-like mutation.

  2. HCK (show HCK ELISA Kits) represents a novel target for therapeutic development in MYD88-mutated Waldenstrom macroglobulinemia and activated-B cell diffuse large B-cell lymphoma, and possibly other diseases driven by mutated MYD88.

  3. We found an that enhanced expression of the TLR4 (show TLR4 ELISA Kits)-MyD88-NF-kB pathway occurs in GDM placentae, which positively correlates with heightened local IR in placentae and higher maternal hyperglycemia. The TLR4 (show TLR4 ELISA Kits)/MyD88/NF-kB pathway may play a potential role in the development of IR in placentae of GDM.

  4. We found that over-expression of CRNDE in astrocytes increased the expression of key factors in the toll (show TLR4 ELISA Kits)-like receptor signaling pathway, especially toll-like receptor-3 (show TLR3 ELISA Kits)-mediated MyD88-independent pathway.We speculated that CRNDE might trigger inflammation to regulate tumorigenesis and tumor development through the toll (show TLR4 ELISA Kits)-like receptor pathway

  5. Data suggest that, in monocytes and macrophages, the interleukin-1B- (IL1B (show IL1B ELISA Kits))-stimulated trans-autophosphorylation of IRAK4 (interleukin-1 receptor-associated kinase 4 (show IRAK4 ELISA Kits)) is initiated by MYD88-induced dimerization of IRAK4 (show IRAK4 ELISA Kits). In contrast, IRAK1 (interleukin-1 receptor-associated kinase 1 (show IRAK1 ELISA Kits)) is inactive in unstimulated monocytes/macrophages and is converted to an active protein kinase (show CDK7 ELISA Kits) in response to IL1B (show IL1B ELISA Kits).

  6. our data suggest a new role of MyD88 in the development of glucose intolerance and hepatic steatosis.

  7. In patient population from Southeast Serbia Myd 88 L265 mutation was not responsible for the development of diffuse large B-cell non Hodgkin lymphoma.

  8. FSTL1 (show FSTL1 ELISA Kits) displays anti-inflammatory effects against oxidized low-density lipoprotein-induced pro-inflammatory cytokine production via a mechanism that involves the TLR4 (show TLR4 ELISA Kits)/MyD88/NF-kappaB (show NFKB1 ELISA Kits) and MAPK (show MAPK1 ELISA Kits) signaling pathways.

  9. The incidence of MYD88 and CD79B (show CD79B ELISA Kits) mutations in patients with CD5 (show CD5 ELISA Kits)(+) DLBCL is lower than that in patients with DLBCL-SS, suggesting that CD5 (show CD5 ELISA Kits)(+) DLBCL is not the same disease as DLBCL-SS in terms of gene mutation status.

  10. NEDDylation of MyD88 regulates NF-kappaB (show NFKB1 ELISA Kits) activity through antagonizing its ubiquitination, suggesting a novel mechanism of modulating NF-kappaB (show NFKB1 ELISA Kits) signaling pathway.

Pig (Porcine) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. These results suggest that porcine circovirus 2 induces IL-8 (show IL8 ELISA Kits) secretion via the TLR2 (show TLR2 ELISA Kits)/MyD88/NF-kappaB (show NFKB1 ELISA Kits) signalling pathway.

  2. At 30 days after autotransplantation of a pig kidney, mRNA expression increases for MyD88.

  3. These results suggest that an MyD88-dependent signaling pathway is present in newborn as well as in adult swine and that it is involved in the innate immune system of these animals.

Cow (Bovine) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. L. rhamnosus GR-1 ameliorates the E. coli-induced disruption of cellular ultrastructure, subsequently reducing the percentage of bovine endometrial epithelial cells apoptosis and limiting inflammatory responses, partly via attenuation of MyD88-dependent and MyD88-independent pathway activation

  2. Modulated cytokine expression in Bovine viral diarrhea virus type 2 infected macrophages was associated with decreased MyD88 expression.

  3. The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis.

  4. MyD88 plays a functional role in transducing LPS (show IRF6 ELISA Kits) signaling from TLR-4 (show TLR4 ELISA Kits) to downstream effector molecules involved in NF-kappaB (show NFKB1 ELISA Kits) activation

Atlantic Salmon (Salmo salar) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. MyD88 interacts with interferon (show IFNA ELISA Kits) regulatory factor (IRF) 3 (show IRF3 ELISA Kits) and IRF7 (show IRF7 ELISA Kits) in Atlantic salmon (Salmo salar)

  2. the salmon MyD88 was cloned and its expression was analysed.

Mouse (Murine) Myeloid Differentiation Primary Response Gene (88) (MYD88) interaction partners

  1. Autophagy contributes to macrophage resistance to Leishmania major. Data, including data from studies in knockout mice, suggest a key resistance mechanism involves endosomal signaling via Tlr3 (show TLR3 ELISA Kits)/7/9 in macrophages; macrophages deficient for Tlr3 (show TLR3 ELISA Kits)/7/9, Unc93b1 (show UNC93B1 ELISA Kits), or MyD88 fail to undergo L. major-induced autophagy. (TLR = Toll (show TLR4 ELISA Kits)-like receptor; Unc93b1 (show UNC93B1 ELISA Kits) = unc-93 (show UNC93B1 ELISA Kits) homolog B1; MyD88 = myeloid differentiation primary response gene 88)

  2. MyD88 inhibitor ST2825 attenuates acute cardiac rejection and promotes donor-specific hyporesponsiveness in stringent skin transplant models

  3. MyD88 has a divergent requirement for cell survival in non-Tregs and Tregs, and a yet-to-be defined survival-independent requirement for Treg function during the response to alloantigen

  4. The aim of this study was to examine the role of the common TLR adaptor protein myeloid-differentiation factor (MyD) 88 in lung epithelium during host defense against K. pneumoniae-induced pneumonia.

  5. TLR2 (show TLR2 ELISA Kits), TLR4 (show TLR4 ELISA Kits) AND MyD88 mediate allergic airway disease (AAD) and Streptococcus pneumoniae-induced suppression of AAD.

  6. miR (show MLXIP ELISA Kits)-23a-5p modulated the innate host defense by promoting mycobacteria survival and inhibiting the activation of autophagy against Mycobacterium tuberculosis through TLR2 (show TLR2 ELISA Kits)/MyD88/NF-kappaB (show NFKB1 ELISA Kits) pathway by targeting TLR2 (show TLR2 ELISA Kits).

  7. results indicate that the R753Q polymorphism alters TLR2 (show TLR2 ELISA Kits) signaling competence, leading to impaired MyD88-TLR2 (show TLR2 ELISA Kits) assembly, reduced phosphorylation of IRAK-1 (show IRAK1 ELISA Kits), diminished activation of MAPKs and NF-kappaB (show NFKB1 ELISA Kits), and deficient induction of cytokines in macrophages infected with M. smegmatis.

  8. our data suggest a new role of MyD88 in the development of glucose intolerance and hepatic steatosis.

  9. this study shows that MyD88-dependent mechanisms are critical for orchestrating lung inflammatory responses, in terms of IL-17A (show IL17A ELISA Kits) production, as well as eosinophil and neutrophil recruitment

  10. a deficiency in MyD88 or CybB (show CYBB ELISA Kits) is associated with impaired bacterial clearance and increased granuloma formation in the lung.

MYD88 Antigen Profile

Antigen Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with MYD88

  • myeloid differentiation primary response gene (88) (myd88-b) Elisa Kit
  • CG2078 gene product from transcript CG2078-RB (Myd88) Elisa Kit
  • myeloid differentiation primary response gene (88) (myd88) Elisa Kit
  • myeloid differentiation primary response factor 88 (Myd88) Elisa Kit
  • myeloid differentiation primary response 88 (myd88) Elisa Kit
  • myeloid differentiation primary response gene 88 (Myd88) Elisa Kit
  • MyD88 adaptor (myd88) Elisa Kit
  • myeloid differentiation factor 88 (myd88) Elisa Kit
  • myeloid differentiation response protein 88 (myd88) Elisa Kit
  • myeloid differentiation primary response gene 88 (myd88) Elisa Kit
  • interleukin-1 receptor-associated kinase 2 (IRAK2) Elisa Kit
  • interleukin-1 receptor-associated kinase 2 (irak2) Elisa Kit
  • interleukin-1 receptor-associated kinase 2 (LOC100228175) Elisa Kit
  • myeloid differentiation primary response 88 (MYD88) Elisa Kit
  • myeloid differentiation primary response 88 (Myd88) Elisa Kit
  • myeloid differentiation primary response gene (88) (MYD88) Elisa Kit
  • CG2078 Elisa Kit
  • Dmel\\CG2078 Elisa Kit
  • DmMyd88 Elisa Kit
  • dMyd88 Elisa Kit
  • EP(2)2535 Elisa Kit
  • GB12344 Elisa Kit
  • irak-2 Elisa Kit
  • kra Elisa Kit
  • LD20892 Elisa Kit
  • MGC84928 Elisa Kit
  • myd88 Elisa Kit
  • MYD88D Elisa Kit
  • Myd88F Elisa Kit
  • NV10640 Elisa Kit
  • XMyD88 Elisa Kit
  • zgc:103541 Elisa Kit

Protein level used designations for MYD88

myeloid differentiation primary response protein MyD88-B , Toll/IL-1 receptor binding protein MyD88-B , CG2078-PA , CG2078-PB , Myd88-PA , Myd88-PB , Myd88F , krapfen , myeloid differentiation primary response factor 88 , myeloid differentiation primary response protein MyD88 , zMyD88 , myeloid differentiation primary response gene (88) , myeloid differentiation primary response gene 88 , myeloid differentiation factor 88 , myeloid differentiation response protein 88 , interleukin-1 receptor-associated kinase-like 2 , interleukin-1 receptor-associated kinase 2 , myeloid differentiation primary response protein 88

GENE ID SPECIES
734302 Xenopus laevis
35956 Drosophila melanogaster
403145 Danio rerio
413194 Apis mellifera
549591 Xenopus (Silurana) tropicalis
100118553 Nasonia vitripennis
100134853 Takifugu rubripes
100136123 Oncorhynchus mykiss
100305041 Ictalurus punctatus
100616081 Amphimedon queenslandica
416118 Gallus gallus
493227 Xenopus (Silurana) tropicalis
100228175 Taeniopygia guttata
4615 Homo sapiens
301059 Rattus norvegicus
477024 Canis lupus familiaris
460269 Pan troglodytes
420420 Gallus gallus
396646 Sus scrofa
444881 Bos taurus
678682 Ovis aries
696494 Macaca mulatta
100169859 Salmo salar
17874 Mus musculus
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