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anti-Human NFKB1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended NFKB1 Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) Antibodies
  • BICDR-1
  • bicdr1
  • ccdc64
  • EBP-1
  • ebp-1
  • KBF1
  • kbf1
  • NF-kappa-B
  • nf-kappa-b
  • nf-kappaB
  • NF-kappaB
  • NF-kappaB1
  • NF-kB
  • NF-KB1
  • NF-kB1
  • NFkappaB
  • NFKB-p50
  • nfkb-p50
  • nfkb-p105
  • NFKB-p105
  • p50
  • p50/p105
  • p105
Epitope
AA 63-113
44
43
42
39
38
36
28
15
13
13
12
11
10
8
7
7
5
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
524
156
136
17
17
14
12
1
1
Host
Rabbit
476
72
4
2
Clonality
Polyclonal
Conjugate
This NFKB1 antibody is un-conjugated
19
16
14
7
7
6
6
6
6
6
6
6
6
5
5
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
422
218
173
110
105
67
44
29
16
9
9
7
4
4
4
1
1
1
Supplier
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Catalog No. ABIN673194
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088326127 ABIN710666 IF (p) IHC (p) WB Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN710651 IF (p) IHC (p) WB Rabbit IgG pSer337 Log in to see Polyclonal
0.00088326127 ABIN908218 IF (p) Alexa Fluor 350 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN908219 IF (p) Alexa Fluor 488 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN908220 IF (p) Alexa Fluor 555 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN908221 IF (p) Alexa Fluor 647 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN673199 IF (p) Cy5.5 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN673197 IF (p) Cy3 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN673201 IF (p) FITC Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN673198 IF (p) Cy5 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN673200 IF (p) Cy7 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN2814970 IF (p) Alexa Fluor 594 Rabbit IgG AA 63-113 Log in to see Polyclonal
0.00088326127 ABIN877238 IF (p) Alexa Fluor 488 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN877242 IF (p) Alexa Fluor 555 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN877240 IF (p) Alexa Fluor 350 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN877239 IF (p) Alexa Fluor 647 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN710670 IF (p) Cy5 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN710669 IF (p) Cy3 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN710673 IF (p) FITC Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal
0.00088326127 ABIN710671 IF (p) Cy5.5 Rabbit IgG AA 880-900, pSer893 Log in to see Polyclonal

Similar anti-NFKB1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 22 Antibodies 39 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Flow Cytometry (FACS) 1 Antibodies 1 Antibodies
Immunochromatography (IC) 4 Antibodies 4 Antibodies
Immunocytochemistry (ICC) 8 Antibodies 12 Antibodies
Immunofluorescence (IF) 30 Antibodies 43 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 24 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 66 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 102 Antibodies

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) Antibodies
Epitope AA 63-113
(44), (43), (42), (39), (38), (36), (28), (15), (13), (13), (12), (11), (10), (8), (7), (7), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(524), (156), (136), (17), (17), (14), (12), (1), (1)
Host Rabbit
(476), (72), (4), (2)
Clonality
Polyclonal
Conjugate This NFKB1 antibody is un-conjugated
(19), (16), (14), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(422), (218), (173), (110), (105), (67), (44), (29), (16), (9), (9), (7), (4), (4), (4), (1), (1), (1)
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Product Details anti-NFKB1 Antibody

Target Details NFKB1 Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human NFKB1
Isotype IgG

Target Details NFKB1

Product Details anti-NFKB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Nfkb P105 / P50 (NFKB1 Antibody Abstract)
Background

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. The proteasome-mediated process ensures the production of both p50 and p105 and preserves their independent function, although processing of NFKB1/p105 also appears to occur post-translationally.

Subcellular location: Cytoplasm, Nucleus


Synonyms: p50, KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, NFKB1
Gene ID 4790
UniProt P19838
Research Area Cancer, Transcription Factors, Innate Immunity, Apoptosis/Necrosis
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-NFKB1 Antibody Target Details NFKB1 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-NFKB1 Antibody Target Details NFKB1 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-NFKB1 Antibody Target Details NFKB1 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-NFKB1 antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1) (AA 63-113) (ABIN673194) Formalin-fixed and paraffin embedded nasal polyps labeled with Anti-NF-ºBp50 Polyclo...
Western Blotting (WB) image for anti-NFKB1 antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1) (AA 63-113) (ABIN673194) Mouse lung lysates probed with Rabbit Anti-NFkB p105/p50 Polyclonal Antibody, Unconju...