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Browse our NFKB1 Proteins (NFKB1)

Full name:
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 Proteins (NFKB1)
On www.antibodies-online.com are 19 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) Proteins from 7 different suppliers available. Additionally we are shipping NFKB1 Antibodies (570) and NFKB1 Kits (77) and many more products for this protein. A total of 715 NFKB1 products are currently listed.
Synonyms:
BICDR-1, bicdr1, ccdc64, EBP-1, KBF1, NF-kappa-B, NF-kappaB, NF-kappaB1, NF-kB, NF-kB1, NFkappaB, NFKB-p50, NFKB-p105, p50, p50/p105, p105
list all proteins Gene Name GeneID UniProt
NFKB1 18033 P25799
NFKB1 4790 P19838
NFKB1 81736  

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NFKB1 Proteins (NFKB1) by Origin

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Top referenced NFKB1 Proteins

  1. Human NFKB1 Protein expressed in Wheat germ - ABIN1312483 : Park, Hong, Park, Yoon, Seo, Hyun, Han, Ham, Hwang, Hong: Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression. in Molecular cancer 2015 (PubMed)

More Proteins for NFKB1 Interaction Partners

Rhesus Monkey Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. TRIM5alpha (show TRIM5 Proteins) represses HIV-1 LTR promoter activity by negatively regulating TAK1 (show NR2C2 Proteins)/TAB1 (show TAB1 Proteins)/TAB2 (show TAB2 Proteins)/TAB3 (show TAB3 Proteins)-complex-mediated NF-kappaB activation.

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. The mRNA expression of TLR4 (show TLR4 Proteins) and NF-kappaB is increased in a neonatal murine model of necrotizing enterocolitis.

  2. NF-kappaB and c-Jun (show JUN Proteins) coregulate lipopolysaccharide-induced Fra-1 (show FOSL1 Proteins) transcription.

  3. Findings reveal a novel role for Par-4 (show F2RL3 Proteins)/NF-kappaB in islet beta cell apoptosis and type 2 diabetes.

  4. The production of inflammatory mediators of IL-6 (show IL6 Proteins) and COX-2 was also significantly attenuated when treated with 1. It may be attributed to inhibiting NFkappaB signaling. Moreover, this polyphenol suppressed p-STAT3 (show STAT3 Proteins) production as well as its downstream proteins response for apoptosis, such as Bcl-2 (show BCL2 Proteins) and Bax (show BAX Proteins). In summary, the study not only afforded our understanding involved in colitis, but also provided the possible thera...

  5. Dexamethasone-induced MuRF1 (show TRIM63 Proteins) upregulation was significantly attenuated in C2C12 myotubes by resveratrol in vitro, but this effect on C2C12 myotubes was abrogated by a knockdown of NF-kappaB, suggesting that the beneficial effect of resveratrol was NF-kappaB dependent. Our findings provide novel information about the ability of resveratrol to prevent or treat muscle atrophy induced by CKD.

  6. These data provide a detailed mechanism for how activated NF-kappaB and BRD4 (show BRD4 Proteins) control epithelial-mesenchymal transition initiation and transcriptional elongation in model airway epithelial cells in vitro and in a murine pulmonary fibrosis model in vivo.

  7. Sam68 (show KHDRBS1 Proteins) is essential for DNA damage-induced NF-kappaB activation and colon tumorigenesis.

  8. Klotho (show KL Proteins) can modulate inflammation via PDLIM2 (show PDLIM2 Proteins)/NF-kappaB p65 (show NFkBP65 Proteins) pathway in cyclosporine A-induced nephropathy.

  9. Mechanistically, GLA (show GLA Proteins) alleviated the infiltration of macrophages and neutrophils in lungs, attenuated the increases of proinflammatory cytokines in lung tissue and bronchoalveolar lavage fluid, and inhibited the activation of NF-kappaB in fibrotic lungs induced by bleomycin. These results provide evidence that GLA (show GLA Proteins) can effectively ameliorate pulmonary fibrosis through the antagonism of leukocyte infiltration and proinfla...

  10. IL-6 (show IL6 Proteins) secreted by bipotential murine oval liver stem cells induces apoptosis of activated hepatic stellate cells by activating NF-kappaappaB-iNOS (show NOS2 Proteins) signaling.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. The positive SDF-1or NF-kappaB expression is significantly correlated with poor prognosis in cervical cancer.

  2. NF-kappaB is a major controller of epithelial-mesenchymal transition and pulmonary fibrosis.

  3. showed that NF-KBp50, p65 (show GORASP1 Proteins) and HIF1a (show HIF1A Proteins) form higher order heteromultimeric complexes overlapping rs7901656, implying synergism of action among TFs governing cellular response to infection and hypoxia

  4. The RIP (show HRB Proteins) kinases (RIPKs) play an essential role in inflammatory signaling and inflammatory cell death. Although RIPK1 (show RIPK1 Proteins), RIPK2 (show RIPK2 Proteins), and RIPK4 (show RIPK4 Proteins) are similar in that they can all activate NF-kappaB and induce NF-kappaB essential modulator ubiquitination, only RIPK2 (show RIPK2 Proteins) is a dual-specificity kinase.

  5. Gastrin-releasing peptide (GRP (show GRP Proteins)) increased the expression of intercellular adhesion molecule-1 (ICAM-1 (show ICAM1 Proteins)) and vascular cell adhesion molecule-1 (VCAM-1 (show VCAM1 Proteins)) by activating nuclear factor-kappaB (NF-kappaB) in endothelial cells.

  6. Using mass spectrometry analysis, this study discovered a distinct phosphorylation site, Ser (show SIGLEC1 Proteins)-176, on YBX1 (show YBX1 Proteins). Overexpression of the YBX1 (show YBX1 Proteins)-S176A (serine-to-alanine) mutant in either HEK293 cells or colon cancer HT29 cells showed dramatically reduced NF-kappaB-activating ability compared with that of WT-YBX1 (show YBX1 Proteins), confirming that Ser (show SIGLEC1 Proteins)-176 phosphorylation is critical for the activation of NF-kappaB by YBX1 (show YBX1 Proteins).

  7. The circular RNA ciRS-7 promotes APP (show APP Proteins) and BACE1 (show BACE Proteins) degradation in an NF-kappaB-dependent manner.

  8. These data provide a detailed mechanism for how activated NF-kappaB and BRD4 (show BRD4 Proteins) control epithelial-mesenchymal transition initiation and transcriptional elongation in model airway epithelial cells in vitro and in a murine pulmonary fibrosis model in vivo.

  9. GNL3L (show GNL3L Proteins)-LDOC1 (show LDOC1 Proteins) interplay regulates cell proliferation through the modulation of NF-kappaB pathway during tumorigenesis.

  10. Nur77 (show NR4A1 Proteins) decreases ET-1 (show EDN1 Proteins) expression by suppressing NF-kappaB and p38 MAPK (show MAPK14 Proteins).

Zebrafish Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. Study indicate an essential role of NF-kappaB in gonadal differentiation.

Pig (Porcine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. inhibition of NF-kappaB increases autophagy via JNK (show MAPK8 Proteins) signaling, and promotes steroidogenesis in porcine granulosa cells

  2. SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. porcine CD74 (show CD74 Proteins) significantly enhanced the inflammatory response by regulating the NF-kappaB signalling pathway during PCV2 infection, which suggests that porcine CD74 (show CD74 Proteins) may be implicated in the pathogenesis of PCV2 infection.

  4. These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B expression by a PPARgamma (show PPARG Proteins)-dependent pathway in porcine peripheral blood mononuclear cells.

Cow (Bovine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Proteins) and bFGF (show FGF2 Proteins) expression through the activation of AP-1 (show JUN Proteins) and NF-kappaB in bovine mammary gland fibroblasts.

  2. Data indicate the involvement of PKC-alpha (show PKCa Proteins) in proMMP-2 activation and inhibition of TIMP-2 (show TIMP2 Proteins) expression by NF-kappaB-MT1-MMP (show MMP14 Proteins)-dependent and -independent pathway.

  3. MMP-1 (show MMP1 Proteins) promotes VEGFR2 (show KDR Proteins) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R Proteins) and activation of NF-kappaB

  4. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Proteins) synthesis in the presence of IL-1beta (show IL1B Proteins) and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Proteins) signalling pathways

NFKB1 Protein Profile

Protein Summary

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NFKB1

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (nfkb1)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1)
  • nuclear factor NF-kappa-B p105 subunit (CpipJ_CPIJ012236)
  • nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (Nfkb1)
  • BICDR-1 protein
  • bicdr1 protein
  • ccdc64 protein
  • EBP-1 protein
  • KBF1 protein
  • NF-kappa-B protein
  • NF-kappaB protein
  • NF-kappaB1 protein
  • NF-kB protein
  • NF-kB1 protein
  • NFkappaB protein
  • NFKB-p50 protein
  • NFKB-p105 protein
  • p50 protein
  • p50/p105 protein
  • p105 protein

Protein level used designations for NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) , nuclear factor NF-kappa-B p105 subunit , nuclear factor kappa-B, subunit 1 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 , nuclear factor NF-kappa-B p105 subunit-like , DNA-binding factor KBF1 , EBP-1 , NF kappaB1 , NF-kappa-B1 p84/NF-kappa-B1 p98 , NF-kappaB p50 , nuclear factor kappaB p50 , nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 , nuclear factor-kappaB p50 , p50 subunit of NF kappaB , p50 subunit of NF-kappaB , DNA binding factor KBF1 , NF-kappabeta , nuclear factor NF-kappa-B p50 subunit , nuclear factor kappa-B DNA binding subunit , BICD-related protein 1 , NF-kB1 precursor protein , bicaudal D-related protein 1 , coiled-coil domain-containing protein 64A , p50 , NF-kB p50 subunit , nuclear factor kappa-B 1 , nuclear factor of kappa light polypeptide enhancer in B-cells 1

GENE ID SPECIES
447632 Xenopus laevis
461406 Pan troglodytes
710324 Macaca mulatta
100142683 Felis catus
100415321 Callithrix jacchus
100461595 Pongo abelii
6044826 Culex quinquefasciatus
100581655 Nomascus leucogenys
18033 Mus musculus
4790 Homo sapiens
565756 Danio rerio
396033 Gallus gallus
442859 Canis lupus familiaris
751869 Sus scrofa
616115 Bos taurus
81736 Rattus norvegicus
100730075 Cavia porcellus
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