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Browse our NFKB1 Proteins (NFKB1)

Full name:
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 Proteins (NFKB1)
On www.antibodies-online.com are 13 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) Proteins from 7 different suppliers available. Additionally we are shipping NFKB1 Antibodies (569) and NFKB1 Kits (52) and many more products for this protein. A total of 683 NFKB1 products are currently listed.
Synonyms:
BICDR-1, bicdr1, ccdc64, EBP-1, KBF1, NF-kappa-B, NF-kappaB, NF-kappaB1, NF-kB, NF-kB1, NFkappaB, NFKB-p50, NFKB-p105, p50, p50/p105, p105
list all proteins Gene Name GeneID UniProt
NFKB1 18033 P25799
NFKB1 4790 P19838
Rat NFKB1 NFKB1 81736  

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NFKB1 Proteins (NFKB1) by Origin

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Top referenced NFKB1 Proteins

  1. Human NFKB1 Protein expressed in Wheat germ - ABIN1312483 : Park, Hong, Park, Yoon, Seo, Hyun, Han, Ham, Hwang, Hong: Anticancer effect of tectochrysin in colon cancer cell via suppression of NF-kappaB activity and enhancement of death receptor expression. in Molecular cancer 2015 (PubMed)

More Proteins for NFKB1 Interaction Partners

Rhesus Monkey Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. TRIM5alpha (show TRIM5 Proteins) represses HIV-1 LTR promoter activity by negatively regulating TAK1 (show NR2C2 Proteins)/TAB1 (show TAB1 Proteins)/TAB2 (show TAB2 Proteins)/TAB3 (show TAB3 Proteins)-complex-mediated NF-kappaB activation.

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. Kdm5a (show KDM5A Proteins) associates with p50 (show LSP1 Proteins) and binds to the Socs1 (show SOCS1 Proteins) promoter region in resting natural killer cells.

  2. 4,7-dimethoxy-5-methyl-1,3-benzodioxole from Antrodia camphorata suppresses LPS (show TLR4 Proteins)-induced nuclear translocation of nuclear factor-kappaB

  3. These results suggest that Il23a (show IL23A Proteins) expression in DCs is synergistically triggered by the PG E2-EP4 (show PTGER4 Proteins)-cAMP-PKA pathway and canonical/non-canonical NF-kappaB pathways and CREB (show CREB1 Proteins) activated by CD40 (show CD40 Proteins) stimulation.

  4. RNF20 (show RNF20 Proteins) and H2Bub1 promotes chronic colonic inflammation and inflammation-associated colorectal cancer in mice and humans, partly by augmenting NF-kappaB activity and attenuating the antitumoral T cell response.

  5. This study has shown that the NMR spectrum of the full-length p65RHR (DNA binding Rel Homology region) of the NF-kappa B heterodimer (p50 (show LSP1 Proteins)/p65 (show NFkBP65 Proteins)) can be assigned almost completely by analysis of the spectra of smaller domains.

  6. When canonical NF-kappaB signaling was ablated specifically in mature B cells, the differentiation and/or persistence of MZ B cells was still abrogated, but follicular B-cell numbers were only mildly affected. However, the mutant cells exhibited increased turnover as well as functional deficiencies upon activation, suggesting that canonical NF-kappaB signals contribute to their long-term persistence and functional fitn...

  7. The kinase IKKalpha (show CHUK Proteins) inhibits activation of the transcription factor NF-kappaB by phosphorylating the regulatory molecule TAX1BP1 (show TAX1BP1 Proteins).

  8. inflammatory signals stimulate the direct interaction of NF-kappaB with response elements to inhibit binding of beta-catenin (show CTNNB1 Proteins) and Runx2 (show RUNX2 Proteins) binding to nearby consensus sites and reduce expression of matrix proteins.

  9. loss of Nrf2 (show NFE2L2 Proteins) or NF-kappaB/RelA (show NFkBP65 Proteins) altered the expression of different genes, and the combination of these alterations likely affects liver homeostasis in the double mutant mice

  10. Data show that TGFbeta (show TGFB1 Proteins)-activated kinase-1 (TAK1 (show NR2C2 Proteins)) activated nuclear factor of activated T-cells (NFAT (show NFATC1 Proteins))/NF-kappa B (NFkappaB), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (show BNIP3 Proteins)), and inhibited cardiac cell death.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. we were able to reproduce previously found associations between PPP1R13L (show PPP1R13L Proteins) and CD3EAP (show CD3EAP Proteins) polymorphisms and lung cancer risk in an increased study group, and we found interactions between NFKB1 rs28362491-PPP1R13L (show PPP1R13L Proteins) rs1970764 and smoking duration and between CD3EAP (show CD3EAP Proteins) rs735482 and smoking duration

  2. From our data we conclude that NFkappaB signaling is activated in precancerous cirrhosis tissues and in a subset of Hepatocellular carcinoma

  3. Paracrine Effect of Degenerated Disc Cells on Healthy Human Nucleus Pulposus Cells Is Mediated by MAPK (show MAPK1 Proteins) and NF-kappaB Pathways and Can Be Reduced by TGF-beta1 (show TGFB1 Proteins)

  4. FSTL1 (show FSTL1 Proteins) plays a critical role in immune regulation, enhancing the antigen presentation ability of dendritic cells by up-regulating NF-kappab expression and down-regulating JNK (show MAPK8 Proteins) expression.

  5. Heterozygosity of rs28362491 in the NF-kappaB1 gene may have a protective effect against oligospermia and could modify the susceptibility of oligospermia in a group with idiopathic male infertility in a Turkish population.

  6. The findings suggest that NFKB1 rs28362491 and TLR2 rs5743708 polymorphisms were significantly associated with morbid obesity through modulation of serum CRP (show CRP Proteins) levels.

  7. Gene expression levels of NF-kappaB1were deregulated in 49 B-cell chronic lymphocytic leukemia, 8 B-cell non-Hodgkin's lymphoma, 3 acute myeloid leukemia, 3 chronic myeloid leukemia, 2 hairy cell leukemia, 2 myelodysplastic syndrome, and 2 T-cell large granular lymphocytic leukemia patients in the post-Chernobyl period.

  8. Data suggest that tripartite motif containing 14 (show TRIM14 Proteins) protein (TRIM14 (show TRIM14 Proteins)) might play an important role in the malignant progression of tongue squamous cells carcinoma (TSCC) and in regulation of the NF_Kappa B (NF-kappaB) signaling pathway.

  9. This study showed that CCL2 (show CCL2 Proteins), NF-kappaB1, RAC2 (show RAC2 Proteins), FCER1G (show FCER1G Proteins) and C1Q may contribute to the generation of neuropathic pain after sciatic nerve injury via immune and defense pathways.

  10. Data indicate that FADD (show FADD Proteins) mediated apoptotic cell death was directed by ubiquitination of cFLIPL and inhibition of NF-kappaB activation.

Zebrafish Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. Study indicate an essential role of NF-kappaB in gonadal differentiation.

Pig (Porcine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. inhibition of NF-kappaB increases autophagy via JNK (show MAPK8 Proteins) signaling, and promotes steroidogenesis in porcine granulosa cells

  2. SIRT1 (show SIRT1 Proteins), p53 (show TP53 Proteins) and NF-kappaB are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. porcine CD74 (show CD74 Proteins) significantly enhanced the inflammatory response by regulating the NF-kappaB signalling pathway during PCV2 infection, which suggests that porcine CD74 (show CD74 Proteins) may be implicated in the pathogenesis of PCV2 infection.

  4. These results suggest that trans-10, cis (show CISH Proteins)-12-conjugated linoleic acid can modulate TNF-alpha (show TNF Proteins) production and NF-kappa B expression by a PPARgamma (show PPARG Proteins)-dependent pathway in porcine peripheral blood mononuclear cells.

Cow (Bovine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) interaction partners

  1. Data indicate the involvement of PKC-alpha (show PKCa Proteins) in proMMP-2 activation and inhibition of TIMP-2 (show TIMP2 Proteins) expression by NF-kappaB-MT1-MMP (show MMP14 Proteins)-dependent and -independent pathway.

  2. MMP-1 (show MMP1 Proteins) promotes VEGFR2 (show KDR Proteins) expression and proliferation of endothelial cells through stimulation of PAR-1 (show F2R Proteins) and activation of NF-kappaB

  3. dynamic compression stimulates cell proliferation and proteoglycan (show Vcan Proteins) synthesis in the presence of IL-1beta (show IL1B Proteins) and/or inhibitors of the MAPKs and NFkappaB and AP-1 (show JUN Proteins) signalling pathways

NFKB1 Protein Profile

Protein Summary

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NFKB1

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (nfkb1)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1)
  • nuclear factor NF-kappa-B p105 subunit (CpipJ_CPIJ012236)
  • nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1)
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (Nfkb1)
  • BICDR-1 protein
  • bicdr1 protein
  • ccdc64 protein
  • EBP-1 protein
  • KBF1 protein
  • NF-kappa-B protein
  • NF-kappaB protein
  • NF-kappaB1 protein
  • NF-kB protein
  • NF-kB1 protein
  • NFkappaB protein
  • NFKB-p50 protein
  • NFKB-p105 protein
  • p50 protein
  • p50/p105 protein
  • p105 protein

Protein level used designations for NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) , nuclear factor NF-kappa-B p105 subunit , nuclear factor kappa-B, subunit 1 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 , nuclear factor NF-kappa-B p105 subunit-like , DNA-binding factor KBF1 , EBP-1 , NF kappaB1 , NF-kappa-B1 p84/NF-kappa-B1 p98 , NF-kappaB p50 , nuclear factor kappaB p50 , nuclear factor of kappa light chain gene enhancer in B-cells 1, p105 , nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 , nuclear factor-kappaB p50 , p50 subunit of NF kappaB , p50 subunit of NF-kappaB , DNA binding factor KBF1 , NF-kappabeta , nuclear factor NF-kappa-B p50 subunit , nuclear factor kappa-B DNA binding subunit , BICD-related protein 1 , NF-kB1 precursor protein , bicaudal D-related protein 1 , coiled-coil domain-containing protein 64A , p50 , NF-kB p50 subunit , nuclear factor kappa-B 1 , nuclear factor of kappa light polypeptide enhancer in B-cells 1

GENE ID SPECIES
447632 Xenopus laevis
461406 Pan troglodytes
710324 Macaca mulatta
100142683 Felis catus
100415321 Callithrix jacchus
100461595 Pongo abelii
6044826 Culex quinquefasciatus
100581655 Nomascus leucogenys
18033 Mus musculus
4790 Homo sapiens
565756 Danio rerio
396033 Gallus gallus
442859 Canis lupus familiaris
751869 Sus scrofa
616115 Bos taurus
81736 Rattus norvegicus
100730075 Cavia porcellus
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