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Browse our anti-NFKBIE (NFKBIE) Antibodies

Full name:
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon Antibodies (NFKBIE)
On www.antibodies-online.com are 97 Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE) Antibodies from 14 different suppliers available. Additionally we are shipping NFKBIE Kits (9) and NFKBIE Proteins (4) and many more products for this protein. A total of 114 NFKBIE products are currently listed.
Synonyms:
IKBE, NFKBIE, Slc35b2
list all antibodies Gene Name GeneID UniProt
NFKBIE 18037 O54910
NFKBIE 4794 O00221
NFKBIE 316241  

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Top referenced anti-NFKBIE Antibodies

  1. Human Polyclonal NFKBIE Primary Antibody for IHC, WB - ABIN362248 : Shirane, Hatakeyama, Hattori, Nakayama, Nakayama: Common pathway for the ubiquitination of IkappaBalpha, IkappaBbeta, and IkappaBepsilon mediated by the F-box protein FWD1. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN362248

  2. Human Polyclonal NFKBIE Primary Antibody for IHC (p), WB - ABIN197570 : McDevitt: Discovering the role of the major histocompatibility complex in the immune response. in Annual review of immunology 2000 (PubMed)
    Show all 4 references for ABIN197570

  3. Human Polyclonal NFKBIE Primary Antibody for IHC, WB - ABIN363012 : Chen, Parent, Maniatis: Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. in Cell 1996 (PubMed)
    Show all 4 references for ABIN363012

  4. Human Polyclonal NFKBIE Primary Antibody for IHC (p), WB - ABIN196948 : Brown, Gerstberger, Carlson, Franzoso, Siebenlist: Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. in Science (New York, N.Y.) 1995 (PubMed)
    Show all 4 references for ABIN196948

More Antibodies against NFKBIE Interaction Partners

Mouse (Murine) Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE) interaction partners

  1. The data imply that regulation of these c-Rel (show NFkBP65 Antibodies)-dependent lymphoid responses is a non-redundant function of IkappaBepsilon.

  2. temporal control of NF-kappaB (show NFKB1 Antibodies) activation by the coordinated degradation and synthesis of IkappaB proteins

  3. IkappaBepsilon deficiency in mice leads to neonatal death, elevated kappaB binding activity, overexpression of NF-kappaB (show NFKB1 Antibodies) target genes, and disruption of lymphocyte production.

  4. Neither IkappaBalpha (show NFKBIA Antibodies) nor IkappaBepsilon deficiency had major effects on natural killer cell generation while their combined absence led to NF-kappaB (show NFKB1 Antibodies) hyperactivation.

  5. An important role is proposed for I kappa B epsilon in the differential regulation of nuclear NF-kappa B (show NFKB1 Antibodies) activity in stimulated B cells.

  6. In vivo degradation rate constants were measured for NF-kappaB (show NFKB1 Antibodies)-bound & -unbound IkappaB. Models suggest differential degradation rates of free & bound IkappaB may be a new cross-regulation mechanism imparting functional robustness to the signaling module.

Human Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE) interaction partners

  1. Newly identified alterations included recurrent promoter mutations of NFKBIE, encoding NF-kappaB (show NFKB1 Antibodies) inhibitor varepsilon (IkappaBvarepsilon), in 14.5% of samples of desmoplastic melanoma

  2. IkappaBepsilon has a role in NF-kappaB (show NFKB1 Antibodies) regulation in aggressive chronic lymphocytic leukemia

  3. Vitamin C forestalls cigarette smoke induced NF-kappaB (show NFKB1 Antibodies) activation in alveolar epithelial cells.

  4. we identified two gene loci associated with rheumatoid arthritis susceptibility- NFKBIE and RTKN2 (show RTKN2 Antibodies)

  5. Protein phosphatase 6 subunit with conserved Sit4-associated protein domain targets IkappaBepsilon

  6. An NFKBIE SNP associated with susceptibility to pneumococcal disease but not pneumococcal empyema.

  7. Expression levels of GGT1 (show GGT1 Antibodies) and possibly NFKBIE might be useful as biomarkers of genetic susceptibility to arsenite.

  8. Genomic mutation of the NFKBIE gene in primary Hodgkin/ Reed Sternberg cells

NFKBIE Antigen Profile

Antigen Summary

The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus.

Alternative names and synonyms associated with NFKBIE

  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (NFKBIE) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon (Nfkbie) antibody
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon (Nfkbie) antibody
  • IKBE antibody
  • NFKBIE antibody
  • Slc35b2 antibody

Protein level used designations for NFKBIE

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon , I-kappa-B-epsilon , NF-kappa-B inhibitor epsilon , NF-kappa-BIE , ikB-E , ikB-epsilon , ikappaBepsilon , solute carrier family 35, member B2

GENE ID SPECIES
462730 Pan troglodytes
609647 Canis lupus familiaris
100591878 Nomascus leucogenys
18037 Mus musculus
4794 Homo sapiens
506727 Bos taurus
316241 Rattus norvegicus
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