anti-Human NGFR antibody for Immunocytochemistry

Recommended NGFR Antibody (supplied by: Log in to see )

Antigen
Nerve Growth Factor Receptor (NGFR) Antibodies
  • ngfr
  • wu:fb38c02
  • wu:fc10h01
  • CD271
  • Gp80-LNGFR
  • TNFRSF16
  • p75(NTR)
  • p75NTR
  • LNGFR
  • RNNGFRR
  • Tnfrsf16
  • p75
  • NRH1b
  • fullback
  • nrh1
  • p75ntr
  • tnfrsf16
  • p75NGFR
  • nerve growth factor receptor
  • neurotrophin receptor associated death domain
  • nerve growth factor receptor (TNFR superfamily, member 16)
  • NGFR
  • nradd
  • Ngfr
  • ngfr
Reactivity
Human
268
109
99
30
28
26
24
12
10
10
8
6
5
5
3
3
2
2
2
1
Host
Mouse
138
122
34
4
1
Clonality
Monoclonal
Conjugate
This NGFR antibody is un-conjugated
19
15
15
13
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
201
109
109
81
67
55
40
31
15
14
13
6
6
6
4
4
3
1
1
1
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Catalog No. ABIN969315
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2869468 ELISA FACS ICC WB Mouse IgG1 Log in to see 2F1C2 4
1 ABIN214454 ICC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN2661630 ICC FACS IF ICFC IP IHC WB FITC Mouse IgG1 kappa Log in to see ME20-4 9
1 ABIN1981852 ICC FACS IP IHC (p) WB Biotin Mouse IgG1 Log in to see NGFR5 4
1 ABIN1873905 ICC IP IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN4904655 ICC IF IHC IP WB Rabbit IgG Log in to see
1 ABIN1176837 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see NGFR5 4
1 ABIN1176838 ICC FACS IHC (p) IP WB PE Mouse IgG1 Log in to see NGFR5 4
1 ABIN2749123 ICC FACS IP IHC (p) WB APC Mouse IgG1 Log in to see NGFR5 4
1 ABIN1002888 ICC ELISA WB Rabbit IgG Log in to see Polyclonal 4
1 ABIN2626107 ICC FACS IHC (p) IP WB Mouse IgG1 Log in to see NGFR5
1 ABIN2661631 ICC FACS IF ICFC IP IHC WB FITC Mouse IgG1 kappa Log in to see ME20-4 10
1 ABIN1737340 ICC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN3199698 FACS ICC IHC (p) IP WB Mouse IgG1 Log in to see NGFR5
1 ABIN1917233 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 407-425, C-Term Log in to see Polyclonal
1 ABIN3199699 FACS ICC IHC (p) IP WB Biotin Mouse IgG1 Log in to see NGFR5
1 ABIN3200889 FACS ICC IHC (p) IP WB APC Mouse IgG1 Log in to see NGFR5
1 ABIN3200890 FACS ICC IHC (p) IP WB PE Mouse IgG1 Log in to see NGFR5
1 ABIN2746981 CM ICC IF IP IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2405068 ICC IP IHC WB Rabbit IgG Log in to see Polyclonal

General

Antigen Nerve Growth Factor Receptor (NGFR) Antibodies
Reactivity Human
(268), (109), (99), (30), (28), (26), (24), (12), (10), (10), (8), (6), (5), (5), (3), (3), (2), (2), (2), (1)
Host Mouse
(138), (122), (34), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This NGFR antibody is un-conjugated
(19), (15), (15), (13), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(201), (109), (109), (81), (67), (55), (40), (31), (15), (14), (13), (6), (6), (6), (4), (4), (3), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-NGFR Antibody

Target Details NGFR Application Details Handling ProductDetails: References for anti-NGFR antibody (ABIN969315) Images
Purification Ascites
Immunogen Purified recombinant fragment of human NGFR expressed in E. Coli.
Clone 2F1C2
Isotype IgG1

Target Details NGFR

Product Details anti-NGFR Antibody Application Details Handling ProductDetails: References for anti-NGFR antibody (ABIN969315) Images back to top
Antigen
Alternative Name NGFR (NGFR Antibody Abstract)
Background Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGFR p75 plays a central role in the regulation of cell number by apoptosis in the developing CNS. During early development, activation of NGFR p75 by NGF induces apoptotic cell death in some neuronal cells, probably through activation of the sphingomyelinase/ceramide pathway, the ICE like proteases and the JNK pathway. In rat Schwann cells, NGF binding to NGFR p75 activates NF kappaB, possibly to modulate Schwann cell migration during nerve regeneration. CD271 has recently been described as being expressed in mesenchymal stem cells (bone marrow stromal cells).
Molecular Weight 45 kDa
Gene ID 4804
HGNC 4804
Research Area Growth Factors, Receptors
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-NGFR Antibody Target Details NGFR Handling ProductDetails: References for anti-NGFR antibody (ABIN969315) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only

Handling

Product Details anti-NGFR Antibody Target Details NGFR Application Details ProductDetails: References for anti-NGFR antibody (ABIN969315) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

ProductDetails: References for anti-NGFR antibody (ABIN969315)

Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling Images back to top
Product cited in:

He, Garcia: "Structure of nerve growth factor complexed with the shared neurotrophin receptor p75." in: Science (New York, N.Y.), Vol. 304, Issue 5672, pp. 870-5, 2004

Hu, Zhang, Qin, Xu, Swaab, Zhou: "Increased p75(NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients." in: Experimental neurology, Vol. 178, Issue 1, pp. 104-11, 2002

Background publications

DiDonato, Hayakawa, Rothwarf, Zandi, Karin: "A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB." in: Nature, Vol. 388, Issue 6642, pp. 548-54, 1997

Fantini, Johansson: "Expression of growth-associated protein 43 and nerve growth factor receptor in human skin: a comparative immunohistochemical investigation." in: The Journal of investigative dermatology, Vol. 99, Issue 6, pp. 734-42, 1993

Images

Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling ProductDetails: References for anti-NGFR antibody (ABIN969315) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN969315) Figure 1: Flow cytometric analysis of EC cells using NGFR mouse mAb (green) and negat...
Immunocytochemistry (ICC) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN969315) Figure 2:Immunofluorescence analysis of EC cells using NGFR mouse mAb (green) . Red: ...
Western Blotting (WB) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (ABIN969315) Figure 3: Western blot analysis using NGFR mouse mAb against NGFR-hIgGFc transfected ...