anti-Human NGFR antibody for Intracellular Flow Cytometry

Recommended NGFR Antibody (supplied by: Log in to see )

Antigen
Nerve Growth Factor Receptor (NGFR) Antibodies
  • ngfr
  • wu:fb38c02
  • wu:fc10h01
  • CD271
  • Gp80-LNGFR
  • TNFRSF16
  • p75(NTR)
  • p75NTR
  • LNGFR
  • RNNGFRR
  • Tnfrsf16
  • p75
  • NRH1b
  • fullback
  • nrh1
  • p75ntr
  • tnfrsf16
  • p75NGFR
  • nerve growth factor receptor
  • neurotrophin receptor associated death domain
  • nerve growth factor receptor (TNFR superfamily, member 16)
  • NGFR
  • nradd
  • Ngfr
  • ngfr
Reactivity
Human
268
109
99
30
28
26
24
12
10
10
8
6
5
5
3
3
2
2
2
1
Host
Mouse
138
122
34
4
1
Clonality
Monoclonal
Conjugate
This NGFR antibody is conjugated to FITC
19
15
14
13
5
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
201
110
109
80
66
55
39
31
15
14
13
6
6
5
4
4
3
1
1
1
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Catalog No. ABIN2661630
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2663264 FACS ICFC PE Mouse IgG1 kappa Log in to see ME20-4 7
1 ABIN2658564 FACS ICFC APC Mouse IgG1 kappa Log in to see ME20-4 8
1 ABIN2661631 ICC FACS IF ICFC IP IHC WB FITC Mouse IgG1 kappa Log in to see ME20-4 10
1 ABIN2663265 FACS ICFC PE Mouse IgG1 kappa Log in to see ME20-4 7
1 ABIN2658565 FACS ICFC APC Mouse IgG1 kappa Log in to see ME20-4 8

General

Antigen Nerve Growth Factor Receptor (NGFR) Antibodies
Reactivity Human
(268), (109), (99), (30), (28), (26), (24), (12), (10), (10), (8), (6), (5), (5), (3), (3), (2), (2), (2), (1)
Host Mouse
(138), (122), (34), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This NGFR antibody is conjugated to FITC
(19), (15), (14), (13), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(201), (110), (109), (80), (66), (55), (39), (31), (15), (14), (13), (6), (6), (5), (4), (4), (3), (1), (1), (1)
Pubmed 9 references available
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Product Details anti-NGFR Antibody

Target Details NGFR Application Details Handling ProductDetails: References for anti-NGFR antibody (ABIN2661630) Images
Cross-Reactivity Monkey, Raccoon (Procyon lotor), Sheep (Ovine), Cat (Feline), Dog (Canine), Pig (Porcine), Rabbit
Purification The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone ME20-4
Isotype IgG1 kappa

Target Details NGFR

Product Details anti-NGFR Antibody Application Details Handling ProductDetails: References for anti-NGFR antibody (ABIN2661630) Images back to top
Antigen
Alternative Name CD271 (NGFR Antibody Abstract)
Background CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Application Details

Product Details anti-NGFR Antibody Target Details NGFR Handling ProductDetails: References for anti-NGFR antibody (ABIN2661630) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-NGFR Antibody Target Details NGFR Application Details ProductDetails: References for anti-NGFR antibody (ABIN2661630) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-NGFR antibody (ABIN2661630)

Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling Images back to top
Background publications

Nakatsugawa, Yamashita, Ochi, Tanaka, Chamoto, Guo, Butler, Hirano: "Specific roles of each TCR hemichain in generating functional chain-centric TCR." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 7, pp. 3487-500, 2015

Aomatsu, Takahashi, Sawada, Okubo, Hasegawa, Taira, Miura, Ishisaki, Chosa: "Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells." in: Scientific reports, Vol. 4, pp. 3652, 2014

Friedman, Li, Li: "Activation of gene transcription by heat shock protein 27 may contribute to its neuronal protection." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 27944-51, 2009

Rock, Onaitis, Rawlins, Lu, Clark, Xue, Randell, Hogan: "Basal cells as stem cells of the mouse trachea and human airway epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 31, pp. 12771-5, 2009

Kidd, Anderson, Schneider: "Postnatal lead exposure alters expression of forebrain p75 and TrkA nerve growth factor receptors." in: Brain research, Vol. 1195, pp. 113-9, 2008

Jansen, Giehl, Nyengaard, Teng, Lioubinski, Sjoegaard, Breiderhoff, Gotthardt, Lin, Eilers, Petersen, Lewin, Hempstead, Willnow, Nykjaer: "Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury." in: Nature neuroscience, Vol. 10, Issue 11, pp. 1449-57, 2007

Peters, Liotiri, Bodó, Hagen, Bíró, Arck, Paus: "Probing the effects of stress mediators on the human hair follicle: substance P holds central position." in: The American journal of pathology, Vol. 171, Issue 6, pp. 1872-86, 2007

Kamke, Brown, Irvine: "Origin and immunolesioning of cholinergic basal forebrain innervation of cat primary auditory cortex." in: Hearing research, Vol. 206, Issue 1-2, pp. 89-106, 2005

Cattoretti, Schiró, Orazi, Soligo, Colombo: "Bone marrow stroma in humans: anti-nerve growth factor receptor antibodies selectively stain reticular cells in vivo and in vitro." in: Blood, Vol. 81, Issue 7, pp. 1726-38, 1993

Images

Product Details anti-NGFR Antibody Target Details NGFR Application Details Handling ProductDetails: References for anti-NGFR antibody (ABIN2661630) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Nerve Growth Factor Receptor (NGFR) antibody (FITC) (ABIN2661630) anti-Nerve Growth Factor Receptor (NGFR) antibody (FITC)